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The map label for this gene is plsC [C]

Identifier: 92112588

GI number: 92112588

Start: 503200

End: 503955

Strand: Direct

Name: plsC [C]

Synonym: Csal_0455

Alternate gene names: 92112588

Gene position: 503200-503955 (Clockwise)

Preceding gene: 92112587

Following gene: 92112591

Centisome position: 13.61

GC content: 65.34

Gene sequence:

>756_bases
ATGAATGTGCTGCGCAGCGTATTGTTCTACGCCGGTTATTTTCTGGCCTTGCTGGTCAGTGGCCTATGCCTGCTGCCGAT
CGCACCCCTGGTCCCGCTGTTTTCGCGGTTTCGACTCCTCAACCTGCATAACCGCTTCATTCTGCGCTGGTTCGCGATCG
CCTGCGGAGTCCGCTACCACGTCAGGGGGCGCGAGAACGTGCCGGAAGGCCCTTGCGTCGTGCTGGCCAATCACCAGAGC
GAATGGGAAACCCTGTTTCTGCAACTGCTCAAGGTGCCCATCTGCACGGTGCTCAAGCGCGAGCTGCTCAATCTGCCGGT
CTTCGGGTGGGGGTTGCGCTTGATCAAGCCCATCGCGCTGGATCGCTCGCGGCCGTCGCGGGCCATGCGCATGGTACTGG
AGCAGGGCATGCAGCGGTTGTCGGAGGGGCTCTCGGTGCTCATCTTCCCGGAAGGCACTCGTGTGGCGCCGGGGCAGCGC
AAGCGCTACAACAAGAGCGGCGTGGTGATCGCCTGTCGCGCCGGCGTGCCGGTCCTCCCGGTGGCTCACAACGCCGGCGA
GCACTGGCCGGGCAAGCATTGGGTCAAGAAGCCGGGACATCTGAATGTGGTCGTGGGCGCGCCGATCGAGACGCAGGGGC
GCTCGGCCGAGGACGTGCTGGCCGAGGTGGAGCACTGGATCGAGGCGCAACTCACCGAGATATCGGCGGTACCGCGCCCC
GCCGCCGAGGGGGAGGCTGCCAAGGTTCCCGCTTGA

Upstream 100 bases:

>100_bases
GCGTGCTGGATGCCTTCGGCATACATCAGAAGCCATGGCGGCTCGAGCTGAGCCGGATGCTGGACGACTGGTGTCGGCTG
CACGACAAGGAGGCGGCGAC

Downstream 100 bases:

>100_bases
TGGCCAGGCGGCGAGATCCCGCCAATGAGGATGGGCAAACGCAAGGGGCGCCTCTCGAGAGGCGCCCCTTGGCATTACGC
GACCGCAAGCGGTATGGCGC

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Domain Protein; Acyltransferase Family Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acyltransferase Domain-Containing Protein; Scaffold Protein; Acylhomoserine Lactone Synthase HdtS; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Phosphoserine Phosphatase; Acetyltransferase Protein; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNVLRSVLFYAGYFLALLVSGLCLLPIAPLVPLFSRFRLLNLHNRFILRWFAIACGVRYHVRGRENVPEGPCVVLANHQS
EWETLFLQLLKVPICTVLKRELLNLPVFGWGLRLIKPIALDRSRPSRAMRMVLEQGMQRLSEGLSVLIFPEGTRVAPGQR
KRYNKSGVVIACRAGVPVLPVAHNAGEHWPGKHWVKKPGHLNVVVGAPIETQGRSAEDVLAEVEHWIEAQLTEISAVPRP
AAEGEAAKVPA

Sequences:

>Translated_251_residues
MNVLRSVLFYAGYFLALLVSGLCLLPIAPLVPLFSRFRLLNLHNRFILRWFAIACGVRYHVRGRENVPEGPCVVLANHQS
EWETLFLQLLKVPICTVLKRELLNLPVFGWGLRLIKPIALDRSRPSRAMRMVLEQGMQRLSEGLSVLIFPEGTRVAPGQR
KRYNKSGVVIACRAGVPVLPVAHNAGEHWPGKHWVKKPGHLNVVVGAPIETQGRSAEDVLAEVEHWIEAQLTEISAVPRP
AAEGEAAKVPA
>Mature_251_residues
MNVLRSVLFYAGYFLALLVSGLCLLPIAPLVPLFSRFRLLNLHNRFILRWFAIACGVRYHVRGRENVPEGPCVVLANHQS
EWETLFLQLLKVPICTVLKRELLNLPVFGWGLRLIKPIALDRSRPSRAMRMVLEQGMQRLSEGLSVLIFPEGTRVAPGQR
KRYNKSGVVIACRAGVPVLPVAHNAGEHWPGKHWVKKPGHLNVVVGAPIETQGRSAEDVLAEVEHWIEAQLTEISAVPRP
AAEGEAAKVPA

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=252, Percent_Identity=30.1587301587302, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI5453718, Length=243, Percent_Identity=29.2181069958848, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI15100175, Length=243, Percent_Identity=29.2181069958848, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=198, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364648, Length=229, Percent_Identity=26.6375545851528, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582856, Length=229, Percent_Identity=26.6375545851528, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582854, Length=229, Percent_Identity=26.6375545851528, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641614, Length=242, Percent_Identity=26.4462809917355, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641612, Length=242, Percent_Identity=26.4462809917355, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 27928; Mature: 27928

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLRSVLFYAGYFLALLVSGLCLLPIAPLVPLFSRFRLLNLHNRFILRWFAIACGVRYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEE
VRGRENVPEGPCVVLANHQSEWETLFLQLLKVPICTVLKRELLNLPVFGWGLRLIKPIAL
ECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
DRSRPSRAMRMVLEQGMQRLSEGLSVLIFPEGTRVAPGQRKRYNKSGVVIACRAGVPVLP
CCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCEEEEECCCCCEEE
VAHNAGEHWPGKHWVKKPGHLNVVVGAPIETQGRSAEDVLAEVEHWIEAQLTEISAVPRP
EECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AAEGEAAKVPA
CCCCCCCCCCC
>Mature Secondary Structure
MNVLRSVLFYAGYFLALLVSGLCLLPIAPLVPLFSRFRLLNLHNRFILRWFAIACGVRYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEE
VRGRENVPEGPCVVLANHQSEWETLFLQLLKVPICTVLKRELLNLPVFGWGLRLIKPIAL
ECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
DRSRPSRAMRMVLEQGMQRLSEGLSVLIFPEGTRVAPGQRKRYNKSGVVIACRAGVPVLP
CCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCEEEEECCCCCEEE
VAHNAGEHWPGKHWVKKPGHLNVVVGAPIETQGRSAEDVLAEVEHWIEAQLTEISAVPRP
EECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AAEGEAAKVPA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA