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The map label for this gene is vllY [H]

Identifier: 92112426

GI number: 92112426

Start: 330650

End: 332497

Strand: Direct

Name: vllY [H]

Synonym: Csal_0292

Alternate gene names: 92112426

Gene position: 330650-332497 (Clockwise)

Preceding gene: 92112420

Following gene: 92112427

Centisome position: 8.94

GC content: 62.28

Gene sequence:

>1848_bases
ATGCGAGCCATTGCAACCGTATGCTTGAGCGGCGATCTGCGTAGCAAGCTAGAGGCCATTGCCCGGGCAGGTTATAGCGG
TGTGGAGATATTCGAGAATGATCTCCTGACCTTCGACGGTTCGCCGAGCGACGTTCGCAGCCTCTGCGAGTCGTTGGGGT
TGGCTATCCTCGCGTTTCAGCCGTTCCGTGACTTCGAGTCGATGCCCGAGCCTCAGCGGCGGCGCAATTTCGAGCGTGCC
GAACGCAAGTTCGACCTGATGGAGGAACTGGGCACCGACTTCCTGCTGGTCTGCAGCAACGTCTCGCCGCAGGCGTTCGA
CGACCTTGGTCGCGCTGCCGAGGATCTGCGCGAGCTGGCCGAGCGCGCCGCGCGCCGCGGACTCCGCATTGGCTTCGAGG
CGCTCGCATGGGGGCGACATATCAGTGATTACCGGGACGCCTGGGATGTCGTAAAGCGCGCTGACCACCCGGCACTGGGC
ATCGTGCTGGACAGTTTCCACATTCTTGCGCGTGGCCACGAATTGGAGACCATGGCCGATATTCCCGCCGAGAAGATTGC
TTTCGTGCAGATCGCCGATGCGCCGCTGCTCGACATGGATGTGCTGCAGTGGAGCCGCCATTTCCGCTGTTTCCCCGGCC
AGGGGCGGTTACCTCTGGCGTCCTTCATGCAGGCGCTGGCGCGCACCGGCTATGCGGGACCGCTGTCGTTGGAGATCTTC
AATGATGCCTTCCGCGCGGCGCCCACCGAAGCTACTGCGATCGATGGACTGCGTTCGCTGATCTGGATCGAGGAACTCGC
CGAGGGCGCGGCCTGGTCCGAGGCGTCGCCGCCCGCGGTGGGCTACGATGGCGTCCATTTCATCGAATTTACGCTCGACG
AGGAGAGTGCCGCGCCGCTCGGCGAGTTCTTCTCGGCGTTGGGCTTTCGCCATATCGGCCGCCATCGCTCGAAGAACGTC
GAGCTATGGCATCAGGGCGACATTCACCTGGTACTCAACTTCGAGACCGATAGCTTCGCGCATACCTTTCGGCTGCTGCA
CGGTACGTCGGTTTGCGCGGTGGGAGTCAGGGTCAACGATCTCGATTCGGCGGTCACTCGAGCGGCGCACTACAAGGCGC
AATGGTTTCGGGGGCCAGTAGGCGAAGGAGAGATGGAGATCCCGGCGCTGCGCGGCATCGAGGGCAGCCTGGTCTATCTG
GTCGACGACGCCCAGGCACGCGAGATGCAGTGGAAGACCGATTTCCACCTCTTCGAGGATGGCCAGGATGATGATGCGGG
ATTGATCAACATCGACCACATCTCCTACGTATTGCCACCAACCCAATTGCTGAGCTGGTTGCTGTTCCACCGCACGGTGT
TTGGCTTCGACGCCGGCCCCGAGCACGAGATCGCCGATCCGCACGGCATGGTGGTCAGTCAGACCGTAACCAGCCCTGAC
AACTCGGTTCGCATTCCGCTGACCGTGTCTTCGGCGCGCGAGACCTTGCCGGGTCGCTTCCTGTCGGAGCACCAGGGCGG
CGTGCAGCAGATCGCCTTCGCCAGTGGCGACATCTTCGCCACCATTGATGCGATGCTTGCGAGAGGTTTGCCGATGCTGC
GCATTCCCGCCAACTACTACGACGACCTGGCGGCCCGCTTTGACCTCGATGATGCATTGCTCGAGGCGATGCGCAGCCGC
AATATTCTCTTCGATCGCAACGACGATGGTGACTTCTTCCACGCCTATACCGAAACCTTCATGGGCCGCTTCTTTTTCGA
GGTGGTCGAGCGGCGTGGCAGCTATTCGCAGTTCGGTGCCGTCAATGCGCCGATCCGCCTGGCGGCCCAGGCCGGCCAGC
AACGTTGA

Upstream 100 bases:

>100_bases
GAACGCTATGCGAACAAAAGCGAGCCGTTCGGCGACCGTTATTCTACATTAGATAATGTTATGTCGACGACGGCCCTTGT
CCGACCACCAGGAGGCTGTC

Downstream 100 bases:

>100_bases
TTTCACGGCGCCCGCCGGGCGCCGGATTGACCTGACATTGAAGGAGTGAGCCATGCGCCTTGGGTTGATCGGCAAGGGCA
TCATGAATTCCAGTTCGCCC

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRAIATVCLSGDLRSKLEAIARAGYSGVEIFENDLLTFDGSPSDVRSLCESLGLAILAFQPFRDFESMPEPQRRRNFERA
ERKFDLMEELGTDFLLVCSNVSPQAFDDLGRAAEDLRELAERAARRGLRIGFEALAWGRHISDYRDAWDVVKRADHPALG
IVLDSFHILARGHELETMADIPAEKIAFVQIADAPLLDMDVLQWSRHFRCFPGQGRLPLASFMQALARTGYAGPLSLEIF
NDAFRAAPTEATAIDGLRSLIWIEELAEGAAWSEASPPAVGYDGVHFIEFTLDEESAAPLGEFFSALGFRHIGRHRSKNV
ELWHQGDIHLVLNFETDSFAHTFRLLHGTSVCAVGVRVNDLDSAVTRAAHYKAQWFRGPVGEGEMEIPALRGIEGSLVYL
VDDAQAREMQWKTDFHLFEDGQDDDAGLINIDHISYVLPPTQLLSWLLFHRTVFGFDAGPEHEIADPHGMVVSQTVTSPD
NSVRIPLTVSSARETLPGRFLSEHQGGVQQIAFASGDIFATIDAMLARGLPMLRIPANYYDDLAARFDLDDALLEAMRSR
NILFDRNDDGDFFHAYTETFMGRFFFEVVERRGSYSQFGAVNAPIRLAAQAGQQR

Sequences:

>Translated_615_residues
MRAIATVCLSGDLRSKLEAIARAGYSGVEIFENDLLTFDGSPSDVRSLCESLGLAILAFQPFRDFESMPEPQRRRNFERA
ERKFDLMEELGTDFLLVCSNVSPQAFDDLGRAAEDLRELAERAARRGLRIGFEALAWGRHISDYRDAWDVVKRADHPALG
IVLDSFHILARGHELETMADIPAEKIAFVQIADAPLLDMDVLQWSRHFRCFPGQGRLPLASFMQALARTGYAGPLSLEIF
NDAFRAAPTEATAIDGLRSLIWIEELAEGAAWSEASPPAVGYDGVHFIEFTLDEESAAPLGEFFSALGFRHIGRHRSKNV
ELWHQGDIHLVLNFETDSFAHTFRLLHGTSVCAVGVRVNDLDSAVTRAAHYKAQWFRGPVGEGEMEIPALRGIEGSLVYL
VDDAQAREMQWKTDFHLFEDGQDDDAGLINIDHISYVLPPTQLLSWLLFHRTVFGFDAGPEHEIADPHGMVVSQTVTSPD
NSVRIPLTVSSARETLPGRFLSEHQGGVQQIAFASGDIFATIDAMLARGLPMLRIPANYYDDLAARFDLDDALLEAMRSR
NILFDRNDDGDFFHAYTETFMGRFFFEVVERRGSYSQFGAVNAPIRLAAQAGQQR
>Mature_615_residues
MRAIATVCLSGDLRSKLEAIARAGYSGVEIFENDLLTFDGSPSDVRSLCESLGLAILAFQPFRDFESMPEPQRRRNFERA
ERKFDLMEELGTDFLLVCSNVSPQAFDDLGRAAEDLRELAERAARRGLRIGFEALAWGRHISDYRDAWDVVKRADHPALG
IVLDSFHILARGHELETMADIPAEKIAFVQIADAPLLDMDVLQWSRHFRCFPGQGRLPLASFMQALARTGYAGPLSLEIF
NDAFRAAPTEATAIDGLRSLIWIEELAEGAAWSEASPPAVGYDGVHFIEFTLDEESAAPLGEFFSALGFRHIGRHRSKNV
ELWHQGDIHLVLNFETDSFAHTFRLLHGTSVCAVGVRVNDLDSAVTRAAHYKAQWFRGPVGEGEMEIPALRGIEGSLVYL
VDDAQAREMQWKTDFHLFEDGQDDDAGLINIDHISYVLPPTQLLSWLLFHRTVFGFDAGPEHEIADPHGMVVSQTVTSPD
NSVRIPLTVSSARETLPGRFLSEHQGGVQQIAFASGDIFATIDAMLARGLPMLRIPANYYDDLAARFDLDDALLEAMRSR
NILFDRNDDGDFFHAYTETFMGRFFFEVVERRGSYSQFGAVNAPIRLAAQAGQQR

Specific function: Not Clear, May Be Involved In An Isomerization Step. [C]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

None

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 68615; Mature: 68615

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIATVCLSGDLRSKLEAIARAGYSGVEIFENDLLTFDGSPSDVRSLCESLGLAILAFQ
CCCCEEEHHCCHHHHHHHHHHHCCCCCCEECCCCEEEECCCHHHHHHHHHHCCEEEEEEC
PFRDFESMPEPQRRRNFERAERKFDLMEELGTDFLLVCSNVSPQAFDDLGRAAEDLRELA
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ERAARRGLRIGFEALAWGRHISDYRDAWDVVKRADHPALGIVLDSFHILARGHELETMAD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHC
IPAEKIAFVQIADAPLLDMDVLQWSRHFRCFPGQGRLPLASFMQALARTGYAGPLSLEIF
CCHHHEEEEEECCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEH
NDAFRAAPTEATAIDGLRSLIWIEELAEGAAWSEASPPAVGYDGVHFIEFTLDEESAAPL
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCH
GEFFSALGFRHIGRHRSKNVELWHQGDIHLVLNFETDSFAHTFRLLHGTSVCAVGVRVND
HHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHCCCEEEEECEECH
LDSAVTRAAHYKAQWFRGPVGEGEMEIPALRGIEGSLVYLVDDAQAREMQWKTDFHLFED
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEEEECCCCHHHCCCCCCCEEECC
GQDDDAGLINIDHISYVLPPTQLLSWLLFHRTVFGFDAGPEHEIADPHGMVVSQTVTSPD
CCCCCCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCC
NSVRIPLTVSSARETLPGRFLSEHQGGVQQIAFASGDIFATIDAMLARGLPMLRIPANYY
CCEEEEEEECCHHHHCCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEECCHHH
DDLAARFDLDDALLEAMRSRNILFDRNDDGDFFHAYTETFMGRFFFEVVERRGSYSQFGA
HHHHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VNAPIRLAAQAGQQR
CCCCHHHHHHCCCCC
>Mature Secondary Structure
MRAIATVCLSGDLRSKLEAIARAGYSGVEIFENDLLTFDGSPSDVRSLCESLGLAILAFQ
CCCCEEEHHCCHHHHHHHHHHHCCCCCCEECCCCEEEECCCHHHHHHHHHHCCEEEEEEC
PFRDFESMPEPQRRRNFERAERKFDLMEELGTDFLLVCSNVSPQAFDDLGRAAEDLRELA
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ERAARRGLRIGFEALAWGRHISDYRDAWDVVKRADHPALGIVLDSFHILARGHELETMAD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHC
IPAEKIAFVQIADAPLLDMDVLQWSRHFRCFPGQGRLPLASFMQALARTGYAGPLSLEIF
CCHHHEEEEEECCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEH
NDAFRAAPTEATAIDGLRSLIWIEELAEGAAWSEASPPAVGYDGVHFIEFTLDEESAAPL
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCH
GEFFSALGFRHIGRHRSKNVELWHQGDIHLVLNFETDSFAHTFRLLHGTSVCAVGVRVND
HHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHCCCEEEEECEECH
LDSAVTRAAHYKAQWFRGPVGEGEMEIPALRGIEGSLVYLVDDAQAREMQWKTDFHLFED
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEEEECCCCHHHCCCCCCCEEECC
GQDDDAGLINIDHISYVLPPTQLLSWLLFHRTVFGFDAGPEHEIADPHGMVVSQTVTSPD
CCCCCCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCC
NSVRIPLTVSSARETLPGRFLSEHQGGVQQIAFASGDIFATIDAMLARGLPMLRIPANYY
CCEEEEEEECCHHHHCCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEECCHHH
DDLAARFDLDDALLEAMRSRNILFDRNDDGDFFHAYTETFMGRFFFEVVERRGSYSQFGA
HHHHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VNAPIRLAAQAGQQR
CCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA