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The map label for this gene is ubiH [H]

Identifier: 92112161

GI number: 92112161

Start: 30148

End: 31350

Strand: Direct

Name: ubiH [H]

Synonym: Csal_0025

Alternate gene names: 92112161

Gene position: 30148-31350 (Clockwise)

Preceding gene: 92112160

Following gene: 92112162

Centisome position: 0.82

GC content: 70.16

Gene sequence:

>1203_bases
ATGCCCCGCAATCGGGTGGATATCGCCATCGTGGGTGGCGGCTTGGTCGGCGCCAGCTTGGCGTGTGCGCTAGCGCCGTT
GATCGAGCGCCATGGGCTGCGGGTCGCGGTGATCGAGGCGGCGCCACTGAACGATGCGCAGGCGGCGACGTTTCAACCCA
GCTTCGACGCCCGGGCCAGCGCCATCGCGCAAGGCTCGCGCCGTCATTTCGAACGCCTGGGGGTGTGGGCGACCATGGCC
GAGCGCGCCACGCCGATTCGTCAGATCCATGTCAGCGAGCGCGGGCGTTTCGGCGCCACCCGGCTGACGGCGGACGAGTT
CGACCTCGACGCGCTGGGCTACGTGATCCCCAATGCCTGGATGGGCCAGGTGCTGCATGCCGCCCTCGGGGCGTTGCCGC
TGACCTGGCATTGTCCGGCGCGTGTCGACGACATCGTGCCGATCGCCGACGGCCACCGCCTGGCGCTCAGCGACGGTGCC
TGCCTGGAGGCAGGGCTCACCGTGCTCGCCGACGGTGGACGCTCGGGGCTCAAGGAACGGCTGGGCATCGCCAGCCAGGC
GCAGCCCTATGAACAGCATGCCTTGATCGCCAACGTCGAGGTCGGTCGTGATCACGGTGGCGTGGCCTACGAGCGGTTCT
CGTCGCAAGGCCCGATGGCGCTGTTGCCGATGGCGGGACGCCGGATGGCGCTGGTCTGGACGCATGCCAGCGAGCGGCGC
GAAGACGCCCTGGCCTGGTCGGACGACGTCTGCCTGAGGCGCCTGCAAGACGCCTTCGGCGACCGCCTGGGACGTTTCCG
GCGCATCGGCCGGCGTGACGCCTATCCGTTGTCGCTGGTCACGGCCAACGAGCCGGTGCGCCCCCATCTGGCGGTGCTGG
GCAATGCCGCGCATGCCCTGCACCCGGTGGCCGGGCAAGGCTTCAACCTCGCCCTGCGGGGCGTGATGGACCTGGTCGCG
ACCCTCGAGGACGGCTTGTCCCGTGGACAGGCACCCGGCGGTGCGGGCCTGCTGGGCGAGTTCGAAAACCGCCGCGCCGC
CGATCGGCGTAACGTGATCCGCTTCAGCGACGGCTTGATCCGCCTGTTCGGCATCGAGCATGCCGCCTTTTCCCACCTGC
GTGCCGCGGGGCTGGTGGGACTCAATATCGTGAGCCCGCTGCGACGCACCCTGGCGCGCCGCGCCATGGGGCTGGAGCGA
TGA

Upstream 100 bases:

>100_bases
GCCCGCCACGACTGCCGTGCATGCCCTTAACGTGGTACAAAACAGCGTGTCCCGCCATCGCCGATGGCGGGACGTTCGGA
GCCGACAGGGAGAGTTTGCG

Downstream 100 bases:

>100_bases
CGGCCGACGAGGAAACGAACATGGAAGAGACGACACACGACGAGGTGATCGTCGTCGGCGGCGGCATGGTCGGTGCCGCG
CTGGCGGCGCTGCTCGGCGA

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MPRNRVDIAIVGGGLVGASLACALAPLIERHGLRVAVIEAAPLNDAQAATFQPSFDARASAIAQGSRRHFERLGVWATMA
ERATPIRQIHVSERGRFGATRLTADEFDLDALGYVIPNAWMGQVLHAALGALPLTWHCPARVDDIVPIADGHRLALSDGA
CLEAGLTVLADGGRSGLKERLGIASQAQPYEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERR
EDALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHALHPVAGQGFNLALRGVMDLVA
TLEDGLSRGQAPGGAGLLGEFENRRAADRRNVIRFSDGLIRLFGIEHAAFSHLRAAGLVGLNIVSPLRRTLARRAMGLER

Sequences:

>Translated_400_residues
MPRNRVDIAIVGGGLVGASLACALAPLIERHGLRVAVIEAAPLNDAQAATFQPSFDARASAIAQGSRRHFERLGVWATMA
ERATPIRQIHVSERGRFGATRLTADEFDLDALGYVIPNAWMGQVLHAALGALPLTWHCPARVDDIVPIADGHRLALSDGA
CLEAGLTVLADGGRSGLKERLGIASQAQPYEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERR
EDALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHALHPVAGQGFNLALRGVMDLVA
TLEDGLSRGQAPGGAGLLGEFENRRAADRRNVIRFSDGLIRLFGIEHAAFSHLRAAGLVGLNIVSPLRRTLARRAMGLER
>Mature_399_residues
PRNRVDIAIVGGGLVGASLACALAPLIERHGLRVAVIEAAPLNDAQAATFQPSFDARASAIAQGSRRHFERLGVWATMAE
RATPIRQIHVSERGRFGATRLTADEFDLDALGYVIPNAWMGQVLHAALGALPLTWHCPARVDDIVPIADGHRLALSDGAC
LEAGLTVLADGGRSGLKERLGIASQAQPYEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERRE
DALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHALHPVAGQGFNLALRGVMDLVAT
LEDGLSRGQAPGGAGLLGEFENRRAADRRNVIRFSDGLIRLFGIEHAAFSHLRAAGLVGLNIVSPLRRTLARRAMGLER

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=422, Percent_Identity=26.303317535545, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI32967307, Length=334, Percent_Identity=27.2455089820359, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=42.5316455696203, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1789273, Length=401, Percent_Identity=31.4214463840399, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786883, Length=404, Percent_Identity=32.1782178217822, Blast_Score=155, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI25146631, Length=434, Percent_Identity=26.2672811059908, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI19920760, Length=424, Percent_Identity=26.1792452830189, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43064; Mature: 42933

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRNRVDIAIVGGGLVGASLACALAPLIERHGLRVAVIEAAPLNDAQAATFQPSFDARAS
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHH
AIAQGSRRHFERLGVWATMAERATPIRQIHVSERGRFGATRLTADEFDLDALGYVIPNAW
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHH
MGQVLHAALGALPLTWHCPARVDDIVPIADGHRLALSDGACLEAGLTVLADGGRSGLKER
HHHHHHHHHCCCCEEEECCCCCCCCEECCCCCEEEECCCCHHHCCCEEEECCCHHHHHHH
LGIASQAQPYEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERR
HCCCCCCCCCHHCEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCEEEEEEECCHHHH
EDALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHH
HPVAGQGFNLALRGVMDLVATLEDGLSRGQAPGGAGLLGEFENRRAADRRNVIRFSDGLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEECCCEE
RLFGIEHAAFSHLRAAGLVGLNIVSPLRRTLARRAMGLER
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PRNRVDIAIVGGGLVGASLACALAPLIERHGLRVAVIEAAPLNDAQAATFQPSFDARAS
CCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHH
AIAQGSRRHFERLGVWATMAERATPIRQIHVSERGRFGATRLTADEFDLDALGYVIPNAW
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHH
MGQVLHAALGALPLTWHCPARVDDIVPIADGHRLALSDGACLEAGLTVLADGGRSGLKER
HHHHHHHHHCCCCEEEECCCCCCCCEECCCCCEEEECCCCHHHCCCEEEECCCHHHHHHH
LGIASQAQPYEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERR
HCCCCCCCCCHHCEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCEEEEEEECCHHHH
EDALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHH
HPVAGQGFNLALRGVMDLVATLEDGLSRGQAPGGAGLLGEFENRRAADRRNVIRFSDGLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEECCCEE
RLFGIEHAAFSHLRAAGLVGLNIVSPLRRTLARRAMGLER
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]