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The map label for this gene is waaA [H]

Identifier: 92112154

GI number: 92112154

Start: 22348

End: 23637

Strand: Direct

Name: waaA [H]

Synonym: Csal_0018

Alternate gene names: 92112154

Gene position: 22348-23637 (Clockwise)

Preceding gene: 92112153

Following gene: 92112156

Centisome position: 0.6

GC content: 69.53

Gene sequence:

>1290_bases
ATGCTCACGCCCCGTCTCGCGCGCGGCCTCTACAGCGGCGCGTTGTATCTCCTGTCGCCCTTGATCTGGTGGCGCGTGTG
GCGTGAGCATGCGCTCACTAACAAGCGTGCGGAACGGTTGGGGTTGATCGCCGCGGTAGACGAGACGCCGACGGTCTGGC
TGCATGCCGCGTCGGTCGGCGAGGTGCTGGCCGCGCGTCCCCTGATCGAGGCCCTGGCCGAACGCCATGCCGATCACCGC
CTCGTGGTCACCACCATGACCGCGACCGGCGCCGAGCGCGTACGGGCGCTGTTTCCCGCCGAGCGCTATGCGCTGACGCA
TTACTTCCTGCCGCTGGACTTTCCGGGCGCGGCGCGGCGCTTCATGAGGCGCTTGCGACCGCGCCTGGCGATCATCGTCG
AAACCGAACTGTGGCCCAACCTGCTGGCGGCGTGCGACCGGCAGCGGGTGCCCGTGGTGGTGGCCAACGCACGGCTCTCG
GAGAAGGCCTTCCAGGGGTATCGCAGGGTGAGGGCACTGCTGCATGGTGCACTGGGTGCGGTGAGCTGGCTGGCGGCCAA
GTCGGAGGCGGACCTGGAGCGCTTCGTGGCGCTGGGGTTGCCCCGCGCACGTGGCGACGTGGTCGGGTCGATAAAATTCG
ATCTGCCGCTCAACGACGGATTTCGTGATGAGGGTAAGCGCTTACATTCAGCCTGGGGAAGACGCTTCGTGTGGGTCGCC
GGTTCCACCCATGACGGCGAAGACGAGCAGGTGCTCGATGCCCATGCCCGGCTGCGTGAGCGCGATCCGCAGGCCTTGCT
GGTCCTGGTGCCACGTCATCCACAGCGCTTCGCGGCCGTGGCCGAGCTCTGCATGGCGCGTGGCGAGCGTATCGCGCGGC
GTTCGCAGGGCGAGACACCCGACGCCGCGACGAGCGTTCTGCTGGTCGACACCATGGGCGAGCTGATGCGCTTCTATGCC
GCGGCGGATGTCGCCTTCGTGGGCGGCAGCCTGATGCCCATCGGCGGACACAATCTGCTCGAGCCCGCCGCACTCGGCGT
GCCGGTGCTCACCGGGCCGCACCTGGAGAATTTCGAGGACATCGCCGCGACCCTGCGCGAGGCACAGGCCCTGCGCGAGG
TGGACGATGCAGCGGCACTGGGAGATGCCCTGGTGGCGCTTGCCGACGACCCCGAGGCGCGCCGCGGGCTGGGAGCCGCC
GGCGAAGCCGTGGTGGACGCCAATCGCGGTGCCCTGGAGGCGACCCTGGCGGGCATCGCCGCGCGGTTGCCGGCCACGCC
GACACGCTAG

Upstream 100 bases:

>100_bases
CATGGCCGCCGGGGGCGAGGTTCGCGTGCTGAACTTCGAGGACGGCGTCTCGACTACCGCCATGATCGACACCATTCTCG
ACCGGGAAGGCTAAGGCGCG

Downstream 100 bases:

>100_bases
CCCGCCACGCCGCGGGAGTGCACGGCCCGTGTCGTCAGGGCGTGTGGCGCTCGACGCCATGCTCCGTTCCCAGCAGCAGC
ACATCCGCACCGCGCTGAGC

Product: three-deoxy-D-manno-octulosonic-acid transferase-like protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLTPRLARGLYSGALYLLSPLIWWRVWREHALTNKRAERLGLIAAVDETPTVWLHAASVGEVLAARPLIEALAERHADHR
LVVTTMTATGAERVRALFPAERYALTHYFLPLDFPGAARRFMRRLRPRLAIIVETELWPNLLAACDRQRVPVVVANARLS
EKAFQGYRRVRALLHGALGAVSWLAAKSEADLERFVALGLPRARGDVVGSIKFDLPLNDGFRDEGKRLHSAWGRRFVWVA
GSTHDGEDEQVLDAHARLRERDPQALLVLVPRHPQRFAAVAELCMARGERIARRSQGETPDAATSVLLVDTMGELMRFYA
AADVAFVGGSLMPIGGHNLLEPAALGVPVLTGPHLENFEDIAATLREAQALREVDDAAALGDALVALADDPEARRGLGAA
GEAVVDANRGALEATLAGIAARLPATPTR

Sequences:

>Translated_429_residues
MLTPRLARGLYSGALYLLSPLIWWRVWREHALTNKRAERLGLIAAVDETPTVWLHAASVGEVLAARPLIEALAERHADHR
LVVTTMTATGAERVRALFPAERYALTHYFLPLDFPGAARRFMRRLRPRLAIIVETELWPNLLAACDRQRVPVVVANARLS
EKAFQGYRRVRALLHGALGAVSWLAAKSEADLERFVALGLPRARGDVVGSIKFDLPLNDGFRDEGKRLHSAWGRRFVWVA
GSTHDGEDEQVLDAHARLRERDPQALLVLVPRHPQRFAAVAELCMARGERIARRSQGETPDAATSVLLVDTMGELMRFYA
AADVAFVGGSLMPIGGHNLLEPAALGVPVLTGPHLENFEDIAATLREAQALREVDDAAALGDALVALADDPEARRGLGAA
GEAVVDANRGALEATLAGIAARLPATPTR
>Mature_429_residues
MLTPRLARGLYSGALYLLSPLIWWRVWREHALTNKRAERLGLIAAVDETPTVWLHAASVGEVLAARPLIEALAERHADHR
LVVTTMTATGAERVRALFPAERYALTHYFLPLDFPGAARRFMRRLRPRLAIIVETELWPNLLAACDRQRVPVVVANARLS
EKAFQGYRRVRALLHGALGAVSWLAAKSEADLERFVALGLPRARGDVVGSIKFDLPLNDGFRDEGKRLHSAWGRRFVWVA
GSTHDGEDEQVLDAHARLRERDPQALLVLVPRHPQRFAAVAELCMARGERIARRSQGETPDAATSVLLVDTMGELMRFYA
AADVAFVGGSLMPIGGHNLLEPAALGVPVLTGPHLENFEDIAATLREAQALREVDDAAALGDALVALADDPEARRGLGAA
GEAVVDANRGALEATLAGIAARLPATPTR

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=420, Percent_Identity=42.6190476190476, Blast_Score=321, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 46788; Mature: 46788

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPRLARGLYSGALYLLSPLIWWRVWREHALTNKRAERLGLIAAVDETPTVWLHAASVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHH
EVLAARPLIEALAERHADHRLVVTTMTATGAERVRALFPAERYALTHYFLPLDFPGAARR
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHCCHHHHHHEEEEEECCCCHHHHH
FMRRLRPRLAIIVETELWPNLLAACDRQRVPVVVANARLSEKAFQGYRRVRALLHGALGA
HHHHCCCCEEEEEECCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VSWLAAKSEADLERFVALGLPRARGDVVGSIKFDLPLNDGFRDEGKRLHSAWGRRFVWVA
HHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEE
GSTHDGEDEQVLDAHARLRERDPQALLVLVPRHPQRFAAVAELCMARGERIARRSQGETP
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DAATSVLLVDTMGELMRFYAAADVAFVGGSLMPIGGHNLLEPAALGVPVLTGPHLENFED
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHCCCCCCCCCCCCCHHH
IAATLREAQALREVDDAAALGDALVALADDPEARRGLGAAGEAVVDANRGALEATLAGIA
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCCEEECCCCHHHHHHHHHH
ARLPATPTR
HHCCCCCCC
>Mature Secondary Structure
MLTPRLARGLYSGALYLLSPLIWWRVWREHALTNKRAERLGLIAAVDETPTVWLHAASVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHH
EVLAARPLIEALAERHADHRLVVTTMTATGAERVRALFPAERYALTHYFLPLDFPGAARR
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHCCHHHHHHEEEEEECCCCHHHHH
FMRRLRPRLAIIVETELWPNLLAACDRQRVPVVVANARLSEKAFQGYRRVRALLHGALGA
HHHHCCCCEEEEEECCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VSWLAAKSEADLERFVALGLPRARGDVVGSIKFDLPLNDGFRDEGKRLHSAWGRRFVWVA
HHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEE
GSTHDGEDEQVLDAHARLRERDPQALLVLVPRHPQRFAAVAELCMARGERIARRSQGETP
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DAATSVLLVDTMGELMRFYAAADVAFVGGSLMPIGGHNLLEPAALGVPVLTGPHLENFED
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHCCCCCCCCCCCCCHHH
IAATLREAQALREVDDAAALGDALVALADDPEARRGLGAAGEAVVDANRGALEATLAGIA
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCCEEECCCCHHHHHHHHHH
ARLPATPTR
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]