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The map label for this gene is dnaA

Identifier: 92112137

GI number: 92112137

Start: 93

End: 1580

Strand: Direct

Name: dnaA

Synonym: Csal_0001

Alternate gene names: 92112137

Gene position: 93-1580 (Clockwise)

Preceding gene: NA

Following gene: 92112138

Centisome position: 0.0

GC content: 61.76

Gene sequence:

>1488_bases
GTGTCGGTCGCTCTCTGGCAGCAATGCCTCAACTTTCTTCAGGACGAACTGAGTTCACAGCAGTTCAACACCTGGATTCG
CCCACTGCAGGCGGAAGACGGTGACGCCAACGAGCTGTGTCTTCTGGCGCCCAACCGCTTCGTGCGTGACTGGGTCAACG
ATAAATACCTGAAGCGCATCAACGAGCTGCTGCGGGACTTGGCATCCGGTAAGCCGCCCAAGGTGCAGCTGACGGTGGGG
AGTCGCCGCAACGTGGCGATGTCGTCGCCGCGTGACCTGGGCGCGCCGGTGTCGGCGACGACGATGAATGCCTCGCGCCC
GACCGAGGCGCCGGCGGTGCATGCCGCTCCGCGTGCCAAGGGGGACTACGCCGACGAGCAGGAAATCGATCGCCTTCGCG
AACGCGAGGAAACGCCGCGGCGCGGTGGTGGCGAGCGCCAGGTCCAGGTGGAGGGGAGTCTCAAGCACCAGAGCGGTCTC
AACCCCAATTTCACCTTCGAGACATTCGTCGAGGGCAAGTCCAACCAGCTTGCGCGTGCCGCGTCGCGGCAGGTCGCCGA
GAACCCCGGTGGTGCCTACAATCCCTTGTTCCTGTACGGTGGGGTCGGTTTGGGGAAGACGCACCTGATGCATGCCGTCG
GCAACCATCTGGCGGGGCAGCGCGAGAACGCCAAGGTCGTCTACCTGCATTCGGAGCGTTTCGTCGCCGACATGGTCAAG
GCGCTACAGCTCAACGCCATCAACGACTTCAAGCGTTTCTATCGCAGCGTGGATGCCCTGCTGATCGATGACATTCAGTT
CTTCGCCGGCAAGGAGCGTTCGCAGGAAGAATTCTTCCACACGTTCAATGCGCTGCTCGAGGGCGGCCAGCAGATGATCC
TGACCTCGGACCGTTATCCCAAGGAAATCAGCGGGGTGGAGGAACGTCTCAAGTCGCGCTTCGGCTGGGGACTGACGGTC
GCCATCGAGCCGCCGGAGCTGGAAACGCGCGTGGCGATCCTGATGAAGAAGGCCGACCAGGCCAAGGTCGATCTCCCGCA
CGATGCTGCCTTCTTCATTGCCCAGAAGATTCGTTCCAACGTGCGCGAATTGGAAGGGGCGCTGAAGAAGGTGATTGCCG
ACTCGCATTTCATGGGCAAGCCGATCACCCAGGATTTCATTCGCGAGTCGCTCAAGGACCTGCTGGCTCTGCAGGACAAG
CAGGTCGGCGTCGACAACATCCAGCGCACGGTGGCGGAGTATTATAAGATCAAGCTGGCCGATCTTCTCTCCAAGCGTCG
TTCGCGCTCGGTCGCGCGGCCGCGTCAGGTGGCCATGGCGCTGGCCAAGGAATTGACCAATCACAGCTTGCCCGAGATCG
GTGATGCCTTCGGTGGGCGCGACCACACCACGGTGCTGCATGCCTGTCGCAAGGTGCAGACACTCAAGGAAGAAAGCGCG
GATATCCGCGAGGACTACAAGAACCTGCTGCGGCTGCTGACCAGTTGA

Upstream 100 bases:

>100_bases
GCCCGGTTTTCCACAGGAAAAGAGAGCGGGGATCCATGTGGATAACCTCGGTCTCGAACGCTACAATACTCGGCCATTCA
TCAACGCTAGGTGAGGTCGT

Downstream 100 bases:

>100_bases
GCATGGCGGCCCGAATATTCCCTTGGACCCCAGGACGAGAGTGGAGCCCATGAGATTTACCATCACCCGCGAAGCCCTAT
TGCGCCCGCTATCGCTGGTC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSVALWQQCLNFLQDELSSQQFNTWIRPLQAEDGDANELCLLAPNRFVRDWVNDKYLKRINELLRDLASGKPPKVQLTVG
SRRNVAMSSPRDLGAPVSATTMNASRPTEAPAVHAAPRAKGDYADEQEIDRLREREETPRRGGGERQVQVEGSLKHQSGL
NPNFTFETFVEGKSNQLARAASRQVAENPGGAYNPLFLYGGVGLGKTHLMHAVGNHLAGQRENAKVVYLHSERFVADMVK
ALQLNAINDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQMILTSDRYPKEISGVEERLKSRFGWGLTV
AIEPPELETRVAILMKKADQAKVDLPHDAAFFIAQKIRSNVRELEGALKKVIADSHFMGKPITQDFIRESLKDLLALQDK
QVGVDNIQRTVAEYYKIKLADLLSKRRSRSVARPRQVAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVQTLKEESA
DIREDYKNLLRLLTS

Sequences:

>Translated_495_residues
MSVALWQQCLNFLQDELSSQQFNTWIRPLQAEDGDANELCLLAPNRFVRDWVNDKYLKRINELLRDLASGKPPKVQLTVG
SRRNVAMSSPRDLGAPVSATTMNASRPTEAPAVHAAPRAKGDYADEQEIDRLREREETPRRGGGERQVQVEGSLKHQSGL
NPNFTFETFVEGKSNQLARAASRQVAENPGGAYNPLFLYGGVGLGKTHLMHAVGNHLAGQRENAKVVYLHSERFVADMVK
ALQLNAINDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQMILTSDRYPKEISGVEERLKSRFGWGLTV
AIEPPELETRVAILMKKADQAKVDLPHDAAFFIAQKIRSNVRELEGALKKVIADSHFMGKPITQDFIRESLKDLLALQDK
QVGVDNIQRTVAEYYKIKLADLLSKRRSRSVARPRQVAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVQTLKEESA
DIREDYKNLLRLLTS
>Mature_494_residues
SVALWQQCLNFLQDELSSQQFNTWIRPLQAEDGDANELCLLAPNRFVRDWVNDKYLKRINELLRDLASGKPPKVQLTVGS
RRNVAMSSPRDLGAPVSATTMNASRPTEAPAVHAAPRAKGDYADEQEIDRLREREETPRRGGGERQVQVEGSLKHQSGLN
PNFTFETFVEGKSNQLARAASRQVAENPGGAYNPLFLYGGVGLGKTHLMHAVGNHLAGQRENAKVVYLHSERFVADMVKA
LQLNAINDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQMILTSDRYPKEISGVEERLKSRFGWGLTVA
IEPPELETRVAILMKKADQAKVDLPHDAAFFIAQKIRSNVRELEGALKKVIADSHFMGKPITQDFIRESLKDLLALQDKQ
VGVDNIQRTVAEYYKIKLADLLSKRRSRSVARPRQVAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVQTLKEESAD
IREDYKNLLRLLTS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=495, Percent_Identity=65.0505050505051, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI226510964, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_CHRSD (Q1R1P2)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572065.1
- ProteinModelPortal:   Q1R1P2
- STRING:   Q1R1P2
- GeneID:   4027320
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0001
- NMPDR:   fig|290398.4.peg.143
- eggNOG:   COG0593
- HOGENOM:   HBG695666
- OMA:   CHTLNAL
- ProtClustDB:   PRK00149
- BioCyc:   CSAL290398:CSAL_0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 55686; Mature: 55555

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVALWQQCLNFLQDELSSQQFNTWIRPLQAEDGDANELCLLAPNRFVRDWVNDKYLKRI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHCHHHHHHH
NELLRDLASGKPPKVQLTVGSRRNVAMSSPRDLGAPVSATTMNASRPTEAPAVHAAPRAK
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GDYADEQEIDRLREREETPRRGGGERQVQVEGSLKHQSGLNPNFTFETFVEGKSNQLARA
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHCCCCCCCCCCHHHHCCCCHHHHHH
ASRQVAENPGGAYNPLFLYGGVGLGKTHLMHAVGNHLAGQRENAKVVYLHSERFVADMVK
HHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHH
ALQLNAINDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQMILTSDRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
KEISGVEERLKSRFGWGLTVAIEPPELETRVAILMKKADQAKVDLPHDAAFFIAQKIRSN
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VRELEGALKKVIADSHFMGKPITQDFIRESLKDLLALQDKQVGVDNIQRTVAEYYKIKLA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DLLSKRRSRSVARPRQVAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVQTLKEESA
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DIREDYKNLLRLLTS
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVALWQQCLNFLQDELSSQQFNTWIRPLQAEDGDANELCLLAPNRFVRDWVNDKYLKRI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHCHHHHHHH
NELLRDLASGKPPKVQLTVGSRRNVAMSSPRDLGAPVSATTMNASRPTEAPAVHAAPRAK
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GDYADEQEIDRLREREETPRRGGGERQVQVEGSLKHQSGLNPNFTFETFVEGKSNQLARA
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHCCCCCCCCCCHHHHCCCCHHHHHH
ASRQVAENPGGAYNPLFLYGGVGLGKTHLMHAVGNHLAGQRENAKVVYLHSERFVADMVK
HHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHH
ALQLNAINDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQMILTSDRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
KEISGVEERLKSRFGWGLTVAIEPPELETRVAILMKKADQAKVDLPHDAAFFIAQKIRSN
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VRELEGALKKVIADSHFMGKPITQDFIRESLKDLLALQDKQVGVDNIQRTVAEYYKIKLA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DLLSKRRSRSVARPRQVAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVQTLKEESA
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DIREDYKNLLRLLTS
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA