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The map label for this gene is moaC [H]

Identifier: 91790500

GI number: 91790500

Start: 4959065

End: 4959550

Strand: Direct

Name: moaC [H]

Synonym: Bpro_4671

Alternate gene names: 91790500

Gene position: 4959065-4959550 (Clockwise)

Preceding gene: 91790497

Following gene: 91790504

Centisome position: 95.36

GC content: 60.7

Gene sequence:

>486_bases
ATGACAACGACTTCTCCGCTGACTCACTTCGACGCGCAAGGCCAGGCCCATATGGTCGACGTGGCCGGCAAGGCCGCAAC
GCACCGTGTTGCCGTTGCCCAGGGTCGCATCACCATGAATCCTGCCACATTGAATCTCATCGTGGAAGGCACGGCAAAAA
AAGGCGACGTACTGGGCGTGGCCAGACTAGCAGGCATCATGGCTGCGAAAAAAACCAGCGAGCTGATCCCCCTGTGCCAT
CCGCTGGCGCTCACGCGCGTGGCGCTTGATTTCAGGGTCGACGCCGCAAGCGCCAGCGTCACCTGCGAGGCGACTGTGGA
AACCGTCGGCCCGACCGGTGTGGAAATGGAAGCATTGACCGCGGTGCAGGTGGCCTTGCTGACGATTTACGACATGTGCA
AGGCGGCGGACCGGGCGATGATCATGACCGATGTGCGCGTGCTTGAAAAGCATGGCGGCAAATCGGGAAGCTTTGTCAAC
CCCTGA

Upstream 100 bases:

>100_bases
CCCAAATGAATGCCCGAGGCATAGAGGCGATGGCCCCAGGAAGATGAACGTGAAAGCATGCTCGTATGATGAGGGATGGT
TGTAAAGGTTTCGTAACAGG

Downstream 100 bases:

>100_bases
GCCGCGTCACTTCAGGTGCTGAAGACGCTCCGGCGCCGCCGCAGCTTCTTGCGCCCAGCGCGCATGCTCCACTGGAAAGG
CCGCCCGATAGCGCGCCAGA

Product: GTP cyclohydrolase subunit MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTTTSPLTHFDAQGQAHMVDVAGKAATHRVAVAQGRITMNPATLNLIVEGTAKKGDVLGVARLAGIMAAKKTSELIPLCH
PLALTRVALDFRVDAASASVTCEATVETVGPTGVEMEALTAVQVALLTIYDMCKAADRAMIMTDVRVLEKHGGKSGSFVN
P

Sequences:

>Translated_161_residues
MTTTSPLTHFDAQGQAHMVDVAGKAATHRVAVAQGRITMNPATLNLIVEGTAKKGDVLGVARLAGIMAAKKTSELIPLCH
PLALTRVALDFRVDAASASVTCEATVETVGPTGVEMEALTAVQVALLTIYDMCKAADRAMIMTDVRVLEKHGGKSGSFVN
P
>Mature_160_residues
TTTSPLTHFDAQGQAHMVDVAGKAATHRVAVAQGRITMNPATLNLIVEGTAKKGDVLGVARLAGIMAAKKTSELIPLCHP
LALTRVALDFRVDAASASVTCEATVETVGPTGVEMEALTAVQVALLTIYDMCKAADRAMIMTDVRVLEKHGGKSGSFVNP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=53.2467532467532, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=154, Percent_Identity=46.7532467532467, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=52, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.0948905109489, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16799; Mature: 16668

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTSPLTHFDAQGQAHMVDVAGKAATHRVAVAQGRITMNPATLNLIVEGTAKKGDVLGV
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEECCEEEEEEEECCCCCCCCHHH
ARLAGIMAAKKTSELIPLCHPLALTRVALDFRVDAASASVTCEATVETVGPTGVEMEALT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCHHHHH
AVQVALLTIYDMCKAADRAMIMTDVRVLEKHGGKSGSFVNP
HHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTTSPLTHFDAQGQAHMVDVAGKAATHRVAVAQGRITMNPATLNLIVEGTAKKGDVLGV
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEECCEEEEEEEECCCCCCCCHHH
ARLAGIMAAKKTSELIPLCHPLALTRVALDFRVDAASASVTCEATVETVGPTGVEMEALT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCHHHHH
AVQVALLTIYDMCKAADRAMIMTDVRVLEKHGGKSGSFVNP
HHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA