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The map label for this gene is purC [H]

Identifier: 91790458

GI number: 91790458

Start: 4909443

End: 4910351

Strand: Reverse

Name: purC [H]

Synonym: Bpro_4629

Alternate gene names: 91790458

Gene position: 4910351-4909443 (Counterclockwise)

Preceding gene: 91790459

Following gene: 91790456

Centisome position: 94.43

GC content: 64.91

Gene sequence:

>909_bases
ATGACTGCTGCGCTCCACACCTCCGCTCTGACTTCCCTGCCCCTGCTTGCCCGCGGCAAGGTGCGCGACAACTACGCCGT
GGGCCAAGACCGGCTGCTGATGGTGGCCAGCGACCGCCTGAGCGCGTTTGATGTGATCCTGGGCGAGCCGATTCCCGGCA
AGGGCGCGCTGCTCACCCAGATGGCGCTGTTCTGGTTTGCCAAGCTGGGCCACCTCTGCCCCAACCACCTCACGGGCGAG
GCGCCCGAGAGCGTGGTCACGGCCGCGGAGCTGCCCCAGGTCACCGGCCGGTCCATGCTGGTCAAGCGCCTCAAGCCCTT
GCCGGTGGAAGCCGTGGTGCGCGGCTACCTGGCTGGCAGCGGCTGGAAGGAATACCAGGAGAGCCAGTCCGTCTGCGGCG
TACCGCTGCCTGCCGGTCTGAAAAACGCCGGCAAATTGCCGGAGCCCATCTTCACGCCGGCCGCCAAGGCCGAGGTCGGC
GAGCATGACGAGAACATCAGCTACGAGCAGGTGGAGAAGGTGGTGGGCCCCGAGCTTGCCGCGCAGATCAAGAAGATCAG
CATCGAAATTTACAAGACCGCGGCGGCCTTTGCGCTGACCAAGGGCATCATCATTGCCGACACCAAGTTCGAGTTCGGCC
TGGACGAAAACGGCACGCTGACGCTGATGGACGAGGTGCTGACACCCGATTCGTCACGCTACTGGCCCATCGAAGGCTAC
GAAGCCGCCTATGCAGCCGGGCTGAACCCGCCCAGCTATGACAAGCAGTTCGTGCGCGACTGGCTGGAGGCCGTGCGCAT
CAACGGCAAGCCCTGGGACAAGACCCCGCCCTCGCCGCAGCTACCGCCCGATGTGGTGGCAAAAACCGCGGCCAAATATC
AGGAGGCTTTAACCCGCTTGGCGGGTTAA

Upstream 100 bases:

>100_bases
CCGCTTTCCCGCCTTCTCCGGATTGGCGATAATTCAAAGCCCGTGCATGCCTTGAGCCGCGCGGGCTTTTTCACTTTTCC
ACCCACCAAGACACCAAGCA

Downstream 100 bases:

>100_bases
AGAGCCCCCCTGTCTCGGCTCACTTCGTGTAGCCGGAACCCCCCAAGGGGGGCGGCGCCTGCGGCCGGGCGAAGCCCGTT
CCGCGGCCCCTGCTTAACAA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTAALHTSALTSLPLLARGKVRDNYAVGQDRLLMVASDRLSAFDVILGEPIPGKGALLTQMALFWFAKLGHLCPNHLTGE
APESVVTAAELPQVTGRSMLVKRLKPLPVEAVVRGYLAGSGWKEYQESQSVCGVPLPAGLKNAGKLPEPIFTPAAKAEVG
EHDENISYEQVEKVVGPELAAQIKKISIEIYKTAAAFALTKGIIIADTKFEFGLDENGTLTLMDEVLTPDSSRYWPIEGY
EAAYAAGLNPPSYDKQFVRDWLEAVRINGKPWDKTPPSPQLPPDVVAKTAAKYQEALTRLAG

Sequences:

>Translated_302_residues
MTAALHTSALTSLPLLARGKVRDNYAVGQDRLLMVASDRLSAFDVILGEPIPGKGALLTQMALFWFAKLGHLCPNHLTGE
APESVVTAAELPQVTGRSMLVKRLKPLPVEAVVRGYLAGSGWKEYQESQSVCGVPLPAGLKNAGKLPEPIFTPAAKAEVG
EHDENISYEQVEKVVGPELAAQIKKISIEIYKTAAAFALTKGIIIADTKFEFGLDENGTLTLMDEVLTPDSSRYWPIEGY
EAAYAAGLNPPSYDKQFVRDWLEAVRINGKPWDKTPPSPQLPPDVVAKTAAKYQEALTRLAG
>Mature_301_residues
TAALHTSALTSLPLLARGKVRDNYAVGQDRLLMVASDRLSAFDVILGEPIPGKGALLTQMALFWFAKLGHLCPNHLTGEA
PESVVTAAELPQVTGRSMLVKRLKPLPVEAVVRGYLAGSGWKEYQESQSVCGVPLPAGLKNAGKLPEPIFTPAAKAEVGE
HDENISYEQVEKVVGPELAAQIKKISIEIYKTAAAFALTKGIIIADTKFEFGLDENGTLTLMDEVLTPDSSRYWPIEGYE
AAYAAGLNPPSYDKQFVRDWLEAVRINGKPWDKTPPSPQLPPDVVAKTAAKYQEALTRLAG

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=300, Percent_Identity=47.6666666666667, Blast_Score=268, Evalue=6e-73,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 32665; Mature: 32534

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALHTSALTSLPLLARGKVRDNYAVGQDRLLMVASDRLSAFDVILGEPIPGKGALLTQ
CCCCHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHH
MALFWFAKLGHLCPNHLTGEAPESVVTAAELPQVTGRSMLVKRLKPLPVEAVVRGYLAGS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GWKEYQESQSVCGVPLPAGLKNAGKLPEPIFTPAAKAEVGEHDENISYEQVEKVVGPELA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCHHHH
AQIKKISIEIYKTAAAFALTKGIIIADTKFEFGLDENGTLTLMDEVLTPDSSRYWPIEGY
HHHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEEHHHHCCCCCCCCCCCCC
EAAYAAGLNPPSYDKQFVRDWLEAVRINGKPWDKTPPSPQLPPDVVAKTAAKYQEALTRL
CHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AG
CC
>Mature Secondary Structure 
TAALHTSALTSLPLLARGKVRDNYAVGQDRLLMVASDRLSAFDVILGEPIPGKGALLTQ
CCCHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHH
MALFWFAKLGHLCPNHLTGEAPESVVTAAELPQVTGRSMLVKRLKPLPVEAVVRGYLAGS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GWKEYQESQSVCGVPLPAGLKNAGKLPEPIFTPAAKAEVGEHDENISYEQVEKVVGPELA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCHHHH
AQIKKISIEIYKTAAAFALTKGIIIADTKFEFGLDENGTLTLMDEVLTPDSSRYWPIEGY
HHHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEEHHHHCCCCCCCCCCCCC
EAAYAAGLNPPSYDKQFVRDWLEAVRINGKPWDKTPPSPQLPPDVVAKTAAKYQEALTRL
CHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA