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The map label for this gene is ccrA [H]

Identifier: 91790366

GI number: 91790366

Start: 4795385

End: 4796344

Strand: Direct

Name: ccrA [H]

Synonym: Bpro_4534

Alternate gene names: 91790366

Gene position: 4795385-4796344 (Clockwise)

Preceding gene: 91790364

Following gene: 91790367

Centisome position: 92.21

GC content: 65.31

Gene sequence:

>960_bases
ATGAGCAGCCCCAAGAAATTCGCCTCCCAAGCCGACCTCGACGAGAAACAGGTCACCTTCACCAGGCTTTCGGACAACGC
CTATGCCTATACGGCCGAAGGCGACCCCAACACCGGCATCGTCATCGGCGACGACTGCGTGCTGGTGGCCGACACCCAGG
CCACACCGGCCATGGCGGCCGACGTGGTGCGCCGCATCCGCGAGGTGACCGACAAGCCCATCAAGTACGTGGTACTGACG
CATTACCACGCGGTGCGTGTGCTGGGCGCCAGCGGCTACCAGCCCGAGCACATCCTGGCCAGCCAGGACACCTACGAGCT
GATCGTCGAACGCGGCGAGCAGGACAAGGCCAGCGAGATCGGCCGCTTCCCGCGCCTGTTCCGCGATGTGGAATCAGTGC
CGCCCGGCCTGACCTGGCCGACCCTGACGTTCACCGGAAAAATGACGCTGTGGCTGGGCCAGCTCGAAGTGCAACTGATC
CAGCTCGGGCGCGGCCACACCAAGGGGGACACAGTGGTCTGGCTGCCCAAGGACAAGATCCTGTTTTCGGGCGACCTGGT
CGAGTTCGACGCGACGCCCTATGCCGGCGACGCCTACTTCAAGGACTGGCCGAAGACGCTGGACAAGCTGGCGGCGCTCA
AGCCGGCGGCACTGGTGCCCGGCCGCGGCGCGGCGCTCACTACCCCCGAGGAAGTGCAGAAGGGTCTGGCCGGCACGCGC
GATTTCATTGCCGACGTGTACGCCAGCGTCCAGGCCGGCGTGAAAGCCGGGAAGGACCTCAACGCGGTCTACAAGGAAAC
CTACGCCAGGCTCAAGCCCAAGTACGGCCACTGGGTGATCTTTGACCACTGCATGCCCTTCGACGTGACCCGCTGCTACG
ACGAGGCGACACAGTACCCCGACCCGCGCATCTGGACGGCCGAGCGCGACCAGCAGATGTGGGAAACGCTGGAAGGTTGA

Upstream 100 bases:

>100_bases
TTTCACAAATGGATTTGACAATAGCAAACTTTTGCATAAAATTAACAAATTGATTTGCAATGGACAAACTCTAATCCTGC
CCGCCAACTCCGGAGATCTC

Downstream 100 bases:

>100_bases
CCCCCTGAGGAGACAAAGATGAAACTGCAAGAACTGCAAGAACTTCCAAACACCCGGGGTCGCGGCGTTGATTACCAGAA
GCTGGCGTTCGACTTTGAGC

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: Cephalosporinase; Imipenem-cefoxitin hydrolyzing enzyme; Penicillinase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSSPKKFASQADLDEKQVTFTRLSDNAYAYTAEGDPNTGIVIGDDCVLVADTQATPAMAADVVRRIREVTDKPIKYVVLT
HYHAVRVLGASGYQPEHILASQDTYELIVERGEQDKASEIGRFPRLFRDVESVPPGLTWPTLTFTGKMTLWLGQLEVQLI
QLGRGHTKGDTVVWLPKDKILFSGDLVEFDATPYAGDAYFKDWPKTLDKLAALKPAALVPGRGAALTTPEEVQKGLAGTR
DFIADVYASVQAGVKAGKDLNAVYKETYARLKPKYGHWVIFDHCMPFDVTRCYDEATQYPDPRIWTAERDQQMWETLEG

Sequences:

>Translated_319_residues
MSSPKKFASQADLDEKQVTFTRLSDNAYAYTAEGDPNTGIVIGDDCVLVADTQATPAMAADVVRRIREVTDKPIKYVVLT
HYHAVRVLGASGYQPEHILASQDTYELIVERGEQDKASEIGRFPRLFRDVESVPPGLTWPTLTFTGKMTLWLGQLEVQLI
QLGRGHTKGDTVVWLPKDKILFSGDLVEFDATPYAGDAYFKDWPKTLDKLAALKPAALVPGRGAALTTPEEVQKGLAGTR
DFIADVYASVQAGVKAGKDLNAVYKETYARLKPKYGHWVIFDHCMPFDVTRCYDEATQYPDPRIWTAERDQQMWETLEG
>Mature_318_residues
SSPKKFASQADLDEKQVTFTRLSDNAYAYTAEGDPNTGIVIGDDCVLVADTQATPAMAADVVRRIREVTDKPIKYVVLTH
YHAVRVLGASGYQPEHILASQDTYELIVERGEQDKASEIGRFPRLFRDVESVPPGLTWPTLTFTGKMTLWLGQLEVQLIQ
LGRGHTKGDTVVWLPKDKILFSGDLVEFDATPYAGDAYFKDWPKTLDKLAALKPAALVPGRGAALTTPEEVQKGLAGTRD
FIADVYASVQAGVKAGKDLNAVYKETYARLKPKYGHWVIFDHCMPFDVTRCYDEATQYPDPRIWTAERDQQMWETLEG

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 35566; Mature: 35434

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPKKFASQADLDEKQVTFTRLSDNAYAYTAEGDPNTGIVIGDDCVLVADTQATPAMAA
CCCCHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCEEECCCEEEEECCCCCHHHHH
DVVRRIREVTDKPIKYVVLTHYHAVRVLGASGYQPEHILASQDTYELIVERGEQDKASEI
HHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCCHHHHH
GRFPRLFRDVESVPPGLTWPTLTFTGKMTLWLGQLEVQLIQLGRGHTKGDTVVWLPKDKI
HHHHHHHHHHHHCCCCCCCCEEEEECEEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCE
LFSGDLVEFDATPYAGDAYFKDWPKTLDKLAALKPAALVPGRGAALTTPEEVQKGLAGTR
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHH
DFIADVYASVQAGVKAGKDLNAVYKETYARLKPKYGHWVIFDHCMPFDVTRCYDEATQYP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCC
DPRIWTAERDQQMWETLEG
CCCEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SSPKKFASQADLDEKQVTFTRLSDNAYAYTAEGDPNTGIVIGDDCVLVADTQATPAMAA
CCCHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCEEECCCEEEEECCCCCHHHHH
DVVRRIREVTDKPIKYVVLTHYHAVRVLGASGYQPEHILASQDTYELIVERGEQDKASEI
HHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCCCCEEECCCCHHHHHHHCCCCCHHHHH
GRFPRLFRDVESVPPGLTWPTLTFTGKMTLWLGQLEVQLIQLGRGHTKGDTVVWLPKDKI
HHHHHHHHHHHHCCCCCCCCEEEEECEEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCE
LFSGDLVEFDATPYAGDAYFKDWPKTLDKLAALKPAALVPGRGAALTTPEEVQKGLAGTR
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHH
DFIADVYASVQAGVKAGKDLNAVYKETYARLKPKYGHWVIFDHCMPFDVTRCYDEATQYP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCC
DPRIWTAERDQQMWETLEG
CCCEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121094; 1956298; 2110145; 8805566; 9416622; 9578564; 10210203 [H]