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The map label for this gene is htpX [H]

Identifier: 91790272

GI number: 91790272

Start: 4687942

End: 4688949

Strand: Reverse

Name: htpX [H]

Synonym: Bpro_4439

Alternate gene names: 91790272

Gene position: 4688949-4687942 (Counterclockwise)

Preceding gene: 91790273

Following gene: 91790271

Centisome position: 90.17

GC content: 68.06

Gene sequence:

>1008_bases
ATGCGTTTCTTTGAACGGCAGGAAGCAGCCCGCGCGCAGACCACGCGGCTGCTGCTGCTCTTTGGCCTGACGGTGCTGGC
GCTGGTGCTGGCTGTCAATGCCGCGCTGGCCCTGAGCTGGCGGCTGGTGACGCCGGGCTTCAGTGGCTACCCGGCCTATT
TCTTTGCCGTCAACACCGGCATGACCCTGCTGTTCGTGCTGGGCGGCTGGTGGCTGGAGACCTCGGCCTTGCAGGGCGGC
GGTGAAAAGCTGGCACGCCGCGCCGGTGCGCGCGAGGCCTGGCCGTCCAGCCGCGCGGCAGAACAGAAGCTGTGCAACAT
CGTCAGCGAACTGGCGATTGCCGCCAGCATGAAGCCGCCGGTGCCCATGGTGCTGGACCGGGAAGAGGGCATCAACGCCT
TTGCCACCGGCTGGGACGAGGACGACGCGGTCGTGGCCGTCACGCGCGGCGCCCTCGACAAGCTGACGCGTGATGAACTG
CAGGGTCTGGTGGCCCACGAATTCAGCCACCTGCGCGAGGGTGATACCCGACTGAACATGCGGCTGGGCGGCATGGTGTT
CGGGCTGGAGATGATTTTCAATCTGGGCCGCAGCATGTGCGAGACCGATGACGACGGCCGCCGTTCCTTCATGGCCTTGC
CGGGCTTCGCGATCATGGCCACCGGCTCCCTCGGCTGGCTGGCGGGGCGGATGCTGAAGGCCGCGGTGTCGCGTCAGCGC
GAGTATCTGGCCGATGCGCGGGCCGTGCAGTTCACGCGCAGCAGAGATGGCCTGGGCGGCGTGCTGCGCAAGGTGGCGGG
CGAGCAGGCGCAGGGCCTGGGCATGCGGCGCAGTCTGCACCCGGCGGTACAGCACATGCTGTTGATCAACGCGAACCCGC
AGACCCGCTGGTTTGCCACCCACCCGCCTCTGTCCGAGCGCATTCTCCGCATCTATGGCCGCCCCATGGTCGCGCTGCCG
GCGCGGTGTGACGATGAGGCGGTCACGCGGCCCGACGCCATCTTCTGA

Upstream 100 bases:

>100_bases
ACTGCGTGTAGCTCCCGCGGCCCTGGCTGGTTTGGAGCCTCCGTAGGTCTCCCCGATCGCCTTGAGGTATCGAAGGGTGA
GGTGACCCGTGGGAATATGA

Downstream 100 bases:

>100_bases
ATCCGGCCAGTACAAGCCATGACTTGTGAATGTGCACGCGGCCCATGATTCGAATGCGGGGCGTGTACACCGCACCAGGT
ACTGGATACTCCCTATAGGG

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRFFERQEAARAQTTRLLLLFGLTVLALVLAVNAALALSWRLVTPGFSGYPAYFFAVNTGMTLLFVLGGWWLETSALQGG
GEKLARRAGAREAWPSSRAAEQKLCNIVSELAIAASMKPPVPMVLDREEGINAFATGWDEDDAVVAVTRGALDKLTRDEL
QGLVAHEFSHLREGDTRLNMRLGGMVFGLEMIFNLGRSMCETDDDGRRSFMALPGFAIMATGSLGWLAGRMLKAAVSRQR
EYLADARAVQFTRSRDGLGGVLRKVAGEQAQGLGMRRSLHPAVQHMLLINANPQTRWFATHPPLSERILRIYGRPMVALP
ARCDDEAVTRPDAIF

Sequences:

>Translated_335_residues
MRFFERQEAARAQTTRLLLLFGLTVLALVLAVNAALALSWRLVTPGFSGYPAYFFAVNTGMTLLFVLGGWWLETSALQGG
GEKLARRAGAREAWPSSRAAEQKLCNIVSELAIAASMKPPVPMVLDREEGINAFATGWDEDDAVVAVTRGALDKLTRDEL
QGLVAHEFSHLREGDTRLNMRLGGMVFGLEMIFNLGRSMCETDDDGRRSFMALPGFAIMATGSLGWLAGRMLKAAVSRQR
EYLADARAVQFTRSRDGLGGVLRKVAGEQAQGLGMRRSLHPAVQHMLLINANPQTRWFATHPPLSERILRIYGRPMVALP
ARCDDEAVTRPDAIF
>Mature_335_residues
MRFFERQEAARAQTTRLLLLFGLTVLALVLAVNAALALSWRLVTPGFSGYPAYFFAVNTGMTLLFVLGGWWLETSALQGG
GEKLARRAGAREAWPSSRAAEQKLCNIVSELAIAASMKPPVPMVLDREEGINAFATGWDEDDAVVAVTRGALDKLTRDEL
QGLVAHEFSHLREGDTRLNMRLGGMVFGLEMIFNLGRSMCETDDDGRRSFMALPGFAIMATGSLGWLAGRMLKAAVSRQR
EYLADARAVQFTRSRDGLGGVLRKVAGEQAQGLGMRRSLHPAVQHMLLINANPQTRWFATHPPLSERILRIYGRPMVALP
ARCDDEAVTRPDAIF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=303, Percent_Identity=29.042904290429, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36833; Mature: 36833

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFERQEAARAQTTRLLLLFGLTVLALVLAVNAALALSWRLVTPGFSGYPAYFFAVNTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEECCC
MTLLFVLGGWWLETSALQGGGEKLARRAGAREAWPSSRAAEQKLCNIVSELAIAASMKPP
HHHHHHHHCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
VPMVLDREEGINAFATGWDEDDAVVAVTRGALDKLTRDELQGLVAHEFSHLREGDTRLNM
CCEEEECCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RLGGMVFGLEMIFNLGRSMCETDDDGRRSFMALPGFAIMATGSLGWLAGRMLKAAVSRQR
EHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCHHHHHHHHHHHHHHHHH
EYLADARAVQFTRSRDGLGGVLRKVAGEQAQGLGMRRSLHPAVQHMLLINANPQTRWFAT
HHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHEEEEECCCCCCEEEC
HPPLSERILRIYGRPMVALPARCDDEAVTRPDAIF
CCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFFERQEAARAQTTRLLLLFGLTVLALVLAVNAALALSWRLVTPGFSGYPAYFFAVNTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEECCC
MTLLFVLGGWWLETSALQGGGEKLARRAGAREAWPSSRAAEQKLCNIVSELAIAASMKPP
HHHHHHHHCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
VPMVLDREEGINAFATGWDEDDAVVAVTRGALDKLTRDELQGLVAHEFSHLREGDTRLNM
CCEEEECCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RLGGMVFGLEMIFNLGRSMCETDDDGRRSFMALPGFAIMATGSLGWLAGRMLKAAVSRQR
EHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCHHHHHHHHHHHHHHHHH
EYLADARAVQFTRSRDGLGGVLRKVAGEQAQGLGMRRSLHPAVQHMLLINANPQTRWFAT
HHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHEEEEECCCCCCEEEC
HPPLSERILRIYGRPMVALPARCDDEAVTRPDAIF
CCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA