Click here to switch to the map view.

The map label for this gene is cbbTC [H]

Identifier: 91790184

GI number: 91790184

Start: 4587179

End: 4589260

Strand: Reverse

Name: cbbTC [H]

Synonym: Bpro_4349

Alternate gene names: 91790184

Gene position: 4589260-4587179 (Counterclockwise)

Preceding gene: 91790185

Following gene: 91790181

Centisome position: 88.25

GC content: 53.51

Gene sequence:

>2082_bases
ATGACTGCTTCATCCCTCTCTCTTATGGCCAATGCAATACGGGCGCTCGCTATCGACGCCGTGGAGCGCGCCAACTCGGG
CCATCCAGGCGCACCCATGGGCATGGCTGACATGGCGGCTGCCTTATGGACTCGTCATCTAAAGCACAACCCGAGCAATC
CAAACTGGTTCAATCGCGACCGATTTGTGTTATCCAACGGCCATGCGTCAGCGCTCCTTTATGCTGTTCTGCATCTGACT
GGCTACGAACTTTCTATCGAAGATATAAAGAACTTCCGGCAGATCCACAGCAAAACTCCGGGTCATCCAGAGCTCGGCAT
TACCCCAGGCATCGAAACCACAACCGGGCCGCTAGGGCAAGGTCTTGGTAATGCGGTCGGTATGGCATTGTCCGAGAAGC
TATTGGCAAATGAATTTAATCGACCGGGATACACCGTTATCGATCACAACACGTACGTCTTTCTTGGCGACGGTTGCTTG
ATGGAAGGCATTAGTCACGAAGTGGCAGCTTTAGCCGGCGCGTGGAAGCTCAACAAACTAGTCGCGCTATACGACGATAA
CGGAATCTCGATTGATGGCAAGGTAGAACCATGGTTTCCTGAAGACACAGCTGCGCGGTTCGCTGCATACGGGTGGAATG
TTCTTGGCCCCATCGACGGCCACGATGGTGAACTCGTGGCGGAAACTATCCGGTGTGCACGGCGGTCGAACACCCAACCG
ACATTAATTATCTGCAAGACGCAAATCGGAAAATACTCGCCCAACCGAGCCAATACACCAAAAGTTCATGGCGAACCATT
GGGCGCCGAAGAAATACAGTTGACCCGTGACGCTATGGAATGGACAGATAAACCGTTCCACATCCCAGCCGATGTCTATG
CAGCATGGAATGCTAGAGATAAAGGCCATACGGCGGAATCCCTTTGGGACGCGCAATTCGCCTCCTATGAAGCCATATAT
CCTGATTTAGGTGCTGAGCTGTACCGGCGGATGCGCGGAGATCTGCCGAACGCTTTTGGGAAACTGGCCCATGAGGCCAT
CGAAAAATCTTGCAACCGGGCCGATAGCGTCGCTTCCCGCAGAGCGTCCCAATTGGCATTGGAAGAATTTACTGCAAAGT
TACCTGAGATGCTGGGAGGTTCAGCGGATCTCACCAGTTCAAATCTTACAAACACCAAGTCTACGAGTAGCTTGCGCTTC
AAAACAGATGGACAGGTTGAAGCTTGCTCCAACGGCAAAGGGGTGGAAGTACCTGGCCGACATATTAACTATGGCGTCCG
TGAGTTCGGCATGGCATCTATCATGAATGGGATTGCGCTGCATGGCGGGCACATACCTTACGGCGGGACTTTTTTAACGT
TCAGTGATTACAGTCGCAACGCTTTGCGAATGGCCGCGCTCATGAAGCTGCGAGTCATTCACGTGTTCACTCACGACTCG
ATAGGCCTCGGTGAGGATGGACCCACCCACCAACCGGTAGAACATGCCGCAAGCCTGCGCTTAATCCCAAACCTTGACGT
GTGGCGCCCCGCAGACACTGTCGAGGCGACAGTTGCGTGGGCGGTGGCGCTTCAGAATAAATCTCAGCCTACGGCGTTGC
TTCTTAGTCGGCAGTCCCTCAAATTTCAGCCCAAAACTGAGACAGATGACGTTTGCAAAGGTGGCTACGTCCTTAAAGAC
CCACCAGAGACTGGAGTCGGCAGGCCCTTGGAGGCAGTACTGATTGCTACTGGTTCAGAAGTCCAGCTTGCCTTACGCGC
GCAAGTATTGCTAGCAGACGCCGGGATTTTGACCAGGGTCGTCTCCATGCCGAGCACGACGACATTTGATAAACAAAGCT
CGCACTATAAGTCCCTGGTGTTACCCAGCAGGTTGCCGCGAATTGCGGTTGAAATGGGTGTTTCGCACGGCTGGTGGAAA
TACGGTTGTTCTGCTGTAGTCGCAATAGATACCTACGGGGAGTCGGCTCCCGCCGAAGTGCTATTCAATCACTTCGGATT
TACGCCTCAGGGTGTCGCGAGTGTTGTGCGCGAGGTCATTTCTAAGCCGCAGCTGTCTCAGCTGGCGCCGTTGACATCAT
GA

Upstream 100 bases:

>100_bases
GCACTACTTCCGTCCCCGCATGAGCAGGCGGATTGCCAAGGATCTGCAATAGCACTGCAGCTGCCCAATAAAAATCTTAC
TGAACCTCAGGCAACCGACA

Downstream 100 bases:

>100_bases
ATGCTTATTAGGAGTGACAGGCTATACCTGTTGTCAATAAGGCCGATGAGCGCCTGCTGACGGATTTGACGTTCTACGAG
TTCAGTAGATCCAAGTTTCG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTASSLSLMANAIRALAIDAVERANSGHPGAPMGMADMAAALWTRHLKHNPSNPNWFNRDRFVLSNGHASALLYAVLHLT
GYELSIEDIKNFRQIHSKTPGHPELGITPGIETTTGPLGQGLGNAVGMALSEKLLANEFNRPGYTVIDHNTYVFLGDGCL
MEGISHEVAALAGAWKLNKLVALYDDNGISIDGKVEPWFPEDTAARFAAYGWNVLGPIDGHDGELVAETIRCARRSNTQP
TLIICKTQIGKYSPNRANTPKVHGEPLGAEEIQLTRDAMEWTDKPFHIPADVYAAWNARDKGHTAESLWDAQFASYEAIY
PDLGAELYRRMRGDLPNAFGKLAHEAIEKSCNRADSVASRRASQLALEEFTAKLPEMLGGSADLTSSNLTNTKSTSSLRF
KTDGQVEACSNGKGVEVPGRHINYGVREFGMASIMNGIALHGGHIPYGGTFLTFSDYSRNALRMAALMKLRVIHVFTHDS
IGLGEDGPTHQPVEHAASLRLIPNLDVWRPADTVEATVAWAVALQNKSQPTALLLSRQSLKFQPKTETDDVCKGGYVLKD
PPETGVGRPLEAVLIATGSEVQLALRAQVLLADAGILTRVVSMPSTTTFDKQSSHYKSLVLPSRLPRIAVEMGVSHGWWK
YGCSAVVAIDTYGESAPAEVLFNHFGFTPQGVASVVREVISKPQLSQLAPLTS

Sequences:

>Translated_693_residues
MTASSLSLMANAIRALAIDAVERANSGHPGAPMGMADMAAALWTRHLKHNPSNPNWFNRDRFVLSNGHASALLYAVLHLT
GYELSIEDIKNFRQIHSKTPGHPELGITPGIETTTGPLGQGLGNAVGMALSEKLLANEFNRPGYTVIDHNTYVFLGDGCL
MEGISHEVAALAGAWKLNKLVALYDDNGISIDGKVEPWFPEDTAARFAAYGWNVLGPIDGHDGELVAETIRCARRSNTQP
TLIICKTQIGKYSPNRANTPKVHGEPLGAEEIQLTRDAMEWTDKPFHIPADVYAAWNARDKGHTAESLWDAQFASYEAIY
PDLGAELYRRMRGDLPNAFGKLAHEAIEKSCNRADSVASRRASQLALEEFTAKLPEMLGGSADLTSSNLTNTKSTSSLRF
KTDGQVEACSNGKGVEVPGRHINYGVREFGMASIMNGIALHGGHIPYGGTFLTFSDYSRNALRMAALMKLRVIHVFTHDS
IGLGEDGPTHQPVEHAASLRLIPNLDVWRPADTVEATVAWAVALQNKSQPTALLLSRQSLKFQPKTETDDVCKGGYVLKD
PPETGVGRPLEAVLIATGSEVQLALRAQVLLADAGILTRVVSMPSTTTFDKQSSHYKSLVLPSRLPRIAVEMGVSHGWWK
YGCSAVVAIDTYGESAPAEVLFNHFGFTPQGVASVVREVISKPQLSQLAPLTS
>Mature_692_residues
TASSLSLMANAIRALAIDAVERANSGHPGAPMGMADMAAALWTRHLKHNPSNPNWFNRDRFVLSNGHASALLYAVLHLTG
YELSIEDIKNFRQIHSKTPGHPELGITPGIETTTGPLGQGLGNAVGMALSEKLLANEFNRPGYTVIDHNTYVFLGDGCLM
EGISHEVAALAGAWKLNKLVALYDDNGISIDGKVEPWFPEDTAARFAAYGWNVLGPIDGHDGELVAETIRCARRSNTQPT
LIICKTQIGKYSPNRANTPKVHGEPLGAEEIQLTRDAMEWTDKPFHIPADVYAAWNARDKGHTAESLWDAQFASYEAIYP
DLGAELYRRMRGDLPNAFGKLAHEAIEKSCNRADSVASRRASQLALEEFTAKLPEMLGGSADLTSSNLTNTKSTSSLRFK
TDGQVEACSNGKGVEVPGRHINYGVREFGMASIMNGIALHGGHIPYGGTFLTFSDYSRNALRMAALMKLRVIHVFTHDSI
GLGEDGPTHQPVEHAASLRLIPNLDVWRPADTVEATVAWAVALQNKSQPTALLLSRQSLKFQPKTETDDVCKGGYVLKDP
PETGVGRPLEAVLIATGSEVQLALRAQVLLADAGILTRVVSMPSTTTFDKQSSHYKSLVLPSRLPRIAVEMGVSHGWWKY
GCSAVVAIDTYGESAPAEVLFNHFGFTPQGVASVVREVISKPQLSQLAPLTS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=706, Percent_Identity=27.4787535410765, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI4507521, Length=706, Percent_Identity=27.4787535410765, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI133778974, Length=601, Percent_Identity=26.1231281198003, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI225637459, Length=616, Percent_Identity=23.2142857142857, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI225637463, Length=507, Percent_Identity=23.8658777120316, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI225637461, Length=507, Percent_Identity=23.8658777120316, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI48994911, Length=682, Percent_Identity=55.2785923753666, Blast_Score=769, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=678, Percent_Identity=54.1297935103245, Blast_Score=738, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=527, Percent_Identity=29.0322580645161, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=679, Percent_Identity=47.1281296023564, Blast_Score=587, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6319593, Length=687, Percent_Identity=42.5036390101892, Blast_Score=517, Evalue=1e-147,
Organism=Drosophila melanogaster, GI24666278, Length=600, Percent_Identity=24.5, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI45551847, Length=284, Percent_Identity=32.7464788732394, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI45550715, Length=284, Percent_Identity=32.7464788732394, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24645119, Length=246, Percent_Identity=33.739837398374, Blast_Score=117, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 75073; Mature: 74942

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASSLSLMANAIRALAIDAVERANSGHPGAPMGMADMAAALWTRHLKHNPSNPNWFNRD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSNGHASALLYAVLHLTGYELSIEDIKNFRQIHSKTPGHPELGITPGIETTTGPLGQ
EEEEECCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
GLGNAVGMALSEKLLANEFNRPGYTVIDHNTYVFLGDGCLMEGISHEVAALAGAWKLNKL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHCEE
VALYDDNGISIDGKVEPWFPEDTAARFAAYGWNVLGPIDGHDGELVAETIRCARRSNTQP
EEEECCCCEEECCEECCCCCCHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCC
TLIICKTQIGKYSPNRANTPKVHGEPLGAEEIQLTRDAMEWTDKPFHIPADVYAAWNARD
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHEECCCCC
KGHTAESLWDAQFASYEAIYPDLGAELYRRMRGDLPNAFGKLAHEAIEKSCNRADSVASR
CCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RASQLALEEFTAKLPEMLGGSADLTSSNLTNTKSTSSLRFKTDGQVEACSNGKGVEVPGR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCC
HINYGVREFGMASIMNGIALHGGHIPYGGTFLTFSDYSRNALRMAALMKLRVIHVFTHDS
CCCCCHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEECCC
IGLGEDGPTHQPVEHAASLRLIPNLDVWRPADTVEATVAWAVALQNKSQPTALLLSRQSL
CCCCCCCCCCCCHHHHHCEEECCCCCCCCCCCHHHHHHHEEEEECCCCCCCEEEEECCCC
KFQPKTETDDVCKGGYVLKDPPETGVGRPLEAVLIATGSEVQLALRAQVLLADAGILTRV
CCCCCCCCCHHHCCCEEECCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHCCHHHHHH
VSMPSTTTFDKQSSHYKSLVLPSRLPRIAVEMGVSHGWWKYGCSAVVAIDTYGESAPAEV
HHCCCCCCCCCCCCHHHHHCCCHHCCHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCHHH
LFNHFGFTPQGVASVVREVISKPQLSQLAPLTS
HHHHCCCCHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
TASSLSLMANAIRALAIDAVERANSGHPGAPMGMADMAAALWTRHLKHNPSNPNWFNRD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSNGHASALLYAVLHLTGYELSIEDIKNFRQIHSKTPGHPELGITPGIETTTGPLGQ
EEEEECCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
GLGNAVGMALSEKLLANEFNRPGYTVIDHNTYVFLGDGCLMEGISHEVAALAGAWKLNKL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHCEE
VALYDDNGISIDGKVEPWFPEDTAARFAAYGWNVLGPIDGHDGELVAETIRCARRSNTQP
EEEECCCCEEECCEECCCCCCHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCC
TLIICKTQIGKYSPNRANTPKVHGEPLGAEEIQLTRDAMEWTDKPFHIPADVYAAWNARD
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHEECCCCC
KGHTAESLWDAQFASYEAIYPDLGAELYRRMRGDLPNAFGKLAHEAIEKSCNRADSVASR
CCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RASQLALEEFTAKLPEMLGGSADLTSSNLTNTKSTSSLRFKTDGQVEACSNGKGVEVPGR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCC
HINYGVREFGMASIMNGIALHGGHIPYGGTFLTFSDYSRNALRMAALMKLRVIHVFTHDS
CCCCCHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEECCC
IGLGEDGPTHQPVEHAASLRLIPNLDVWRPADTVEATVAWAVALQNKSQPTALLLSRQSL
CCCCCCCCCCCCHHHHHCEEECCCCCCCCCCCHHHHHHHEEEEECCCCCCCEEEEECCCC
KFQPKTETDDVCKGGYVLKDPPETGVGRPLEAVLIATGSEVQLALRAQVLLADAGILTRV
CCCCCCCCCHHHCCCEEECCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHCCHHHHHH
VSMPSTTTFDKQSSHYKSLVLPSRLPRIAVEMGVSHGWWKYGCSAVVAIDTYGESAPAEV
HHCCCCCCCCCCCCHHHHHCCCHHCCHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCHHH
LFNHFGFTPQGVASVVREVISKPQLSQLAPLTS
HHHHCCCCHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226680; 2559876 [H]