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The map label for this gene is proA [H]

Identifier: 91790157

GI number: 91790157

Start: 4553673

End: 4554356

Strand: Direct

Name: proA [H]

Synonym: Bpro_4321

Alternate gene names: 91790157

Gene position: 4553673-4554356 (Clockwise)

Preceding gene: 91790156

Following gene: 91790158

Centisome position: 87.57

GC content: 64.47

Gene sequence:

>684_bases
ATGACGACACTCGGAATCGTCAAACGCAACATCGTTCGCGCAGACCGCGGCGCCATTGAAACGCTGGGCCGCGTCGGCTC
GGCCACATCGCACGAAGCCATGGGCCGGGTCGGCCTGATGAAACCCTATATGCGGCCCATCTATCCCGGCGCGCAGGTCG
CAGGCCCGGCTGTGACGGTACTGCTGCATCCGGGCGACAACTGGATGATGCATGTGGTTGCCGAACAGATCCAGCCCGGC
GATGTCGTCGTGGCCGCCATCACGGCCGAATGCACCGACGGCTATTTCGGTGACCTGCTCGCTACCTCGTTCATGGCGCG
TGGCGCAGTCGCGCTGGTCATCGACGCGGGCTGCCGCGACATCAAAACGCTGAAAGAGATGGGCTTCCCGGTCTGGAGCA
AGGCGATCAGCGCCAAGGGCACCATCAAGGCCACGCTCGGCTCCGTGAACATCCCCGTCGTTTGCGCGAGCGCGCTGGTC
AATCCCGGTGACGTGATCGTTGCGGATGACGACGGCGTCACCGTGGTTCCCGCGGATTGGGCCGTGAAGACCGCTGAAGC
CGCCGCGACCCGCGAAGCCCTGGAAGGGGAAAAACGGGCCAAGCTCGCCGCAGGTGTGCTGGGCCTGGACATGTACAGGA
TGCGCGAGCCGCTTGAGAAGGCCGGCCTGAAGTACATCGATTGA

Upstream 100 bases:

>100_bases
AGATCCTGAGCGATGAAGACAGACACCAGATTTACGAAGGCAATTCGCGGCGAGTCTTCCCGCGGCTCGATGCGCTGTTG
AAAGCGAAAGGACTCTGACC

Downstream 100 bases:

>100_bases
GCCCTGCATGAAATTTGAAAAAACACCCGGTTGGCTGGATTGGTACGCCGGCCCCAGCCAACCGCAATTCAAGCTGCCAC
CCGGTAGCGTCGATGCGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTTLGIVKRNIVRADRGAIETLGRVGSATSHEAMGRVGLMKPYMRPIYPGAQVAGPAVTVLLHPGDNWMMHVVAEQIQPG
DVVVAAITAECTDGYFGDLLATSFMARGAVALVIDAGCRDIKTLKEMGFPVWSKAISAKGTIKATLGSVNIPVVCASALV
NPGDVIVADDDGVTVVPADWAVKTAEAAATREALEGEKRAKLAAGVLGLDMYRMREPLEKAGLKYID

Sequences:

>Translated_227_residues
MTTLGIVKRNIVRADRGAIETLGRVGSATSHEAMGRVGLMKPYMRPIYPGAQVAGPAVTVLLHPGDNWMMHVVAEQIQPG
DVVVAAITAECTDGYFGDLLATSFMARGAVALVIDAGCRDIKTLKEMGFPVWSKAISAKGTIKATLGSVNIPVVCASALV
NPGDVIVADDDGVTVVPADWAVKTAEAAATREALEGEKRAKLAAGVLGLDMYRMREPLEKAGLKYID
>Mature_226_residues
TTLGIVKRNIVRADRGAIETLGRVGSATSHEAMGRVGLMKPYMRPIYPGAQVAGPAVTVLLHPGDNWMMHVVAEQIQPGD
VVVAAITAECTDGYFGDLLATSFMARGAVALVIDAGCRDIKTLKEMGFPVWSKAISAKGTIKATLGSVNIPVVCASALVN
PGDVIVADDDGVTVVPADWAVKTAEAAATREALEGEKRAKLAAGVLGLDMYRMREPLEKAGLKYID

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 23875; Mature: 23744

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLGIVKRNIVRADRGAIETLGRVGSATSHEAMGRVGLMKPYMRPIYPGAQVAGPAVTV
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCEEEE
LLHPGDNWMMHVVAEQIQPGDVVVAAITAECTDGYFGDLLATSFMARGAVALVIDAGCRD
EEECCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHH
IKTLKEMGFPVWSKAISAKGTIKATLGSVNIPVVCASALVNPGDVIVADDDGVTVVPADW
HHHHHHCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCEEEECCC
AVKTAEAAATREALEGEKRAKLAAGVLGLDMYRMREPLEKAGLKYID
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTLGIVKRNIVRADRGAIETLGRVGSATSHEAMGRVGLMKPYMRPIYPGAQVAGPAVTV
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCEEEE
LLHPGDNWMMHVVAEQIQPGDVVVAAITAECTDGYFGDLLATSFMARGAVALVIDAGCRD
EEECCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHH
IKTLKEMGFPVWSKAISAKGTIKATLGSVNIPVVCASALVNPGDVIVADDDGVTVVPADW
HHHHHHCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCEEEECCC
AVKTAEAAATREALEGEKRAKLAAGVLGLDMYRMREPLEKAGLKYID
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]