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The map label for this gene is pldA [C]

Identifier: 91790122

GI number: 91790122

Start: 4518141

End: 4519388

Strand: Direct

Name: pldA [C]

Synonym: Bpro_4284

Alternate gene names: 91790122

Gene position: 4518141-4519388 (Clockwise)

Preceding gene: 91790121

Following gene: 91790124

Centisome position: 86.88

GC content: 67.47

Gene sequence:

>1248_bases
ATGTCCCTCCCCCTGCCTCTCCAACGATTCACTCCGGCCCGCCGCCTGCCCTGCGCCCTTATGCTCGCCGGCCTGCTGAC
CGGCGCGGCGCAGGCCCAAGCCGTGCCGGCGGCCGGTGTGCCGCTCCAGCGTCCGGCCAGCGAGGGCTGGCAGGCTTGCC
AGGCCCTGAAAAACGATCCCGCGGCGCAGCTGACGTGTTTTCAGCAATGGGCGGACTCGCAATCGCCCGCCGCAGCGCCT
GCGGGCACGGCAGCCGGCAAGCCGGCACCCACGCTGACCACCGCACCGGCCAACCCGGACACGGGCCAGCCGGCCATGCC
GGTGCTGGTGCTGCCCGCCATGAACAGCGATGCACCGGACGGCAAACCGCTCGGCTGCAAAAACGACCAGTACGGCGTGC
TCTCCAGGTTCTGGGAACTGCAGCGCGGCACCGACTGCGATACCTTTTCCCTGCGCGGCTACCGGCCCACCTCGCTGGCC
GTCTCGGCCTCCGACAGCGTGAACACCCAGCCGTCATCGACGGCCGCCGGCCACACGGCCCTGACGGCGCAGGCCTATGG
CCGCACCGAGAACAAAATCCAGCTGTCGGTCCGCACCAAGATCGCCAAGGGCCTGCTCAAAAGCGGCCCTGCGGACCAGG
ACGACCACGACTCGCTGTGGTTTGGCTACACCCAGCAAAGTTACTGGCAGCTGTTCAACGGCGGACTGTCACGCCCGTTT
CGCAATACCGACCATGAACCCGAGCTGATCTATATCTACCCGCACCAGATTCCGCTGGCCGGTGGCTGGAACTACCGGCT
CTCCGGGCTGGGGCTGGTGCACCAGTCCAACGGGCAGTCGCTGCCGCTGTCACGCAGCTGGAACCGCGTCTACCTGATGG
GTGCGGCCGAGAAAACACTGGCCGGCGACTCCAGCCTGACACTGCAGGGCCGGGTCTGGGACCGGCTGCGCGAGTCGTCC
GGCAATGACGACAACCCCGGCATCGAAAACTACGTGGGCCGCGCAGAACTGACCGGCGCCTGGCAGATCAACAAGGCCCA
CAGCCTGGGCCTCACGATGCGGCATTCGCTGCGCAAGGAGGCCCGTGGCTCGGCCCGCCTGGACTGGATGGTGGGGCCCG
CGTCCTCATCCAGCTACACCGGCCTGCGCTACCACGTGCAGTTGTTCAGCGGCTATGGCGACAGCCTGCTGGACTTCAAC
AGAAAGCGCACTGTGTTGAGCCTGGGCCTGAGCGTGGTGGATTGGTAG

Upstream 100 bases:

>100_bases
GGAAAGACACCAGCAGCAGCGCACCGGCCAACGCGCCCGACGTGCCCTTCACCCTGACCCGATTACCTTGAGGATTTCAC
CCGCCGTGATGACTGACGCC

Downstream 100 bases:

>100_bases
TCCTCCTTCGCTGCAGCTTCAGGGCGCCCCGATCTTGCCGTGCGCCCGCACCAGGCAATCGTGAAAGGCCTGTACCACGC
GCGACGGCTGGGGGGAACGC

Product: phospholipase A1

Products: NA

Alternate protein names: Phosphatidylcholine 1-acylhydrolase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSLPLPLQRFTPARRLPCALMLAGLLTGAAQAQAVPAAGVPLQRPASEGWQACQALKNDPAAQLTCFQQWADSQSPAAAP
AGTAAGKPAPTLTTAPANPDTGQPAMPVLVLPAMNSDAPDGKPLGCKNDQYGVLSRFWELQRGTDCDTFSLRGYRPTSLA
VSASDSVNTQPSSTAAGHTALTAQAYGRTENKIQLSVRTKIAKGLLKSGPADQDDHDSLWFGYTQQSYWQLFNGGLSRPF
RNTDHEPELIYIYPHQIPLAGGWNYRLSGLGLVHQSNGQSLPLSRSWNRVYLMGAAEKTLAGDSSLTLQGRVWDRLRESS
GNDDNPGIENYVGRAELTGAWQINKAHSLGLTMRHSLRKEARGSARLDWMVGPASSSSYTGLRYHVQLFSGYGDSLLDFN
RKRTVLSLGLSVVDW

Sequences:

>Translated_415_residues
MSLPLPLQRFTPARRLPCALMLAGLLTGAAQAQAVPAAGVPLQRPASEGWQACQALKNDPAAQLTCFQQWADSQSPAAAP
AGTAAGKPAPTLTTAPANPDTGQPAMPVLVLPAMNSDAPDGKPLGCKNDQYGVLSRFWELQRGTDCDTFSLRGYRPTSLA
VSASDSVNTQPSSTAAGHTALTAQAYGRTENKIQLSVRTKIAKGLLKSGPADQDDHDSLWFGYTQQSYWQLFNGGLSRPF
RNTDHEPELIYIYPHQIPLAGGWNYRLSGLGLVHQSNGQSLPLSRSWNRVYLMGAAEKTLAGDSSLTLQGRVWDRLRESS
GNDDNPGIENYVGRAELTGAWQINKAHSLGLTMRHSLRKEARGSARLDWMVGPASSSSYTGLRYHVQLFSGYGDSLLDFN
RKRTVLSLGLSVVDW
>Mature_414_residues
SLPLPLQRFTPARRLPCALMLAGLLTGAAQAQAVPAAGVPLQRPASEGWQACQALKNDPAAQLTCFQQWADSQSPAAAPA
GTAAGKPAPTLTTAPANPDTGQPAMPVLVLPAMNSDAPDGKPLGCKNDQYGVLSRFWELQRGTDCDTFSLRGYRPTSLAV
SASDSVNTQPSSTAAGHTALTAQAYGRTENKIQLSVRTKIAKGLLKSGPADQDDHDSLWFGYTQQSYWQLFNGGLSRPFR
NTDHEPELIYIYPHQIPLAGGWNYRLSGLGLVHQSNGQSLPLSRSWNRVYLMGAAEKTLAGDSSLTLQGRVWDRLRESSG
NDDNPGIENYVGRAELTGAWQINKAHSLGLTMRHSLRKEARGSARLDWMVGPASSSSYTGLRYHVQLFSGYGDSLLDFNR
KRTVLSLGLSVVDW

Specific function: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities [H]

COG id: COG2829

COG function: function code M; Outer membrane phospholipase A

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein. Note=One of the very few enzymes located there (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phospholipase A1 family [H]

Homologues:

Organism=Escherichia coli, GI2367300, Length=272, Percent_Identity=30.1470588235294, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003187 [H]

Pfam domain/function: PF02253 PLA1 [H]

EC number: =3.1.1.32; =3.1.1.4 [H]

Molecular weight: Translated: 44849; Mature: 44718

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPLPLQRFTPARRLPCALMLAGLLTGAAQAQAVPAAGVPLQRPASEGWQACQALKNDP
CCCCCCHHHCCCHHHCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAQLTCFQQWADSQSPAAAPAGTAAGKPAPTLTTAPANPDTGQPAMPVLVLPAMNSDAPD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCC
GKPLGCKNDQYGVLSRFWELQRGTDCDTFSLRGYRPTSLAVSASDSVNTQPSSTAAGHTA
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEE
LTAQAYGRTENKIQLSVRTKIAKGLLKSGPADQDDHDSLWFGYTQQSYWQLFNGGLSRPF
EEHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCC
RNTDHEPELIYIYPHQIPLAGGWNYRLSGLGLVHQSNGQSLPLSRSWNRVYLMGAAEKTL
CCCCCCCCEEEECCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEECCHHHH
AGDSSLTLQGRVWDRLRESSGNDDNPGIENYVGRAELTGAWQINKAHSLGLTMRHSLRKE
CCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCEECEEEEECCHHHCCHHHHHHHHHH
ARGSARLDWMVGPASSSSYTGLRYHVQLFSGYGDSLLDFNRKRTVLSLGLSVVDW
HCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCEEEECCCHHCCC
>Mature Secondary Structure 
SLPLPLQRFTPARRLPCALMLAGLLTGAAQAQAVPAAGVPLQRPASEGWQACQALKNDP
CCCCCHHHCCCHHHCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAQLTCFQQWADSQSPAAAPAGTAAGKPAPTLTTAPANPDTGQPAMPVLVLPAMNSDAPD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCC
GKPLGCKNDQYGVLSRFWELQRGTDCDTFSLRGYRPTSLAVSASDSVNTQPSSTAAGHTA
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEE
LTAQAYGRTENKIQLSVRTKIAKGLLKSGPADQDDHDSLWFGYTQQSYWQLFNGGLSRPF
EEHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCC
RNTDHEPELIYIYPHQIPLAGGWNYRLSGLGLVHQSNGQSLPLSRSWNRVYLMGAAEKTL
CCCCCCCCEEEECCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEECCHHHH
AGDSSLTLQGRVWDRLRESSGNDDNPGIENYVGRAELTGAWQINKAHSLGLTMRHSLRKE
CCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCEECEEEEECCHHHCCHHHHHHHHHH
ARGSARLDWMVGPASSSSYTGLRYHVQLFSGYGDSLLDFNRKRTVLSLGLSVVDW
HCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]