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The map label for this gene is smtA [C]

Identifier: 91790098

GI number: 91790098

Start: 4490189

End: 4491514

Strand: Direct

Name: smtA [C]

Synonym: Bpro_4260

Alternate gene names: 91790098

Gene position: 4490189-4491514 (Clockwise)

Preceding gene: 91790097

Following gene: 91790100

Centisome position: 86.35

GC content: 65.69

Gene sequence:

>1326_bases
ATGCCCGACAACTACCTGCCGCAGGTCAGAAGCCAGTACGAAGCCCTGCCCTACCCGCCGTGCAATCCGGAGGACGACCG
CCAGCGGCTGGTGCTGACCTGGCTGGAAGACCTGCCGATGATCAATCACTACTGCTTTGCCGGAAAGCAGTCGTTTCGCA
ACGGTTTCAGGGCCCTGGTGGCGGGTGGCGGCACCGGGGACGCCACGATCTTCCTGGCCGAGCAGCTGCGCGCCACCGAC
GCACAGATCGTGCACCTGGACATGAGCGAGGCCAGCATCGCGCTGGCAAAGGAAAGGGCGCGCATTCGCGGCCTGAGCAA
CATCACCTGGGTGCACGACTCGCTGCTCAACCTGCCCCATCTGGGCCTGGCGCCCTTCGACTACATCAACTGCAGCGGCG
TGCTGCACCACCTGGCCGACCCCGACCTGGGCTTCCGGGCCCTGCGCGCGGTGCTCAAACCCGAGGGGGCCATCGGCCTG
ATGGTGTACGCCACGGCGGGGCGCACCGGGGTCTACCAGATGCAGGCCCTGATGCGGCTCGTCAACGGCACGCAGGCTGA
CGACCAGCGCAAGATTGCCAATACCCGCGACCTGCTGGCCAGCCTGCCGCCCAGCAACTGGTTCAAGCGCAGCGAAGACC
TGCACCACGACCACAAGGCCGGGGACGCCGGCATCTACGACCTGCTGCTGCATTCGCAGGACCGCTCGTACTCGGTGGGC
GAACTGTTTGACTGGCTGGGGCACGACGCCGCAGGCACGGGAGGGCACGGCCTGCACCTCGAATTTACCGACGTGCAGCG
CGGCCGTTCGCCCTACCTGCCGCACATGGTGCTGGGCAGCCAGCCACCGGCCATGGCCGGCGAACTGCGCAAGATGCCGC
GCCGACGGCAGTATGAGATGGCCGAGCTGATGATAGGCAACCTCATCACCCATTCGCTGTACGTCACGCGCGATGCCGGC
TGTACCGCGCCTTACGGCAATGCCGAATACGTGCCTTTTTTCTTCCATGAGCCGCTGACCGGCGACATCGCGGCACAGGT
CTTCAGCAGCAACCGCGGCCAGCCCTTCCTGCTCCGGCACCAGCACTCCGGCGTGTCGGTGATGGTCAACCCCGGCCGAT
ATGGGCCGCAAATCCTTCGCCTGATTGACGGCCAGAGAACATTCGGCGAGATTTTTGATCAGTTTCGCGCCGACTGGCGC
GGCCAGGCGGCCGCGCCGGACAACGCGGCGCTGTTTGCCGACTTTTCCGAATCATTTGACGTGCTGAACGCGCTGGACCG
CCTGCTGCTGAAGCATCCGCAAGCCGACGCGGCTAAGGCGCCTTAG

Upstream 100 bases:

>100_bases
GGTTCCACGCCGTCACTTGGTCTGGGCGGCTGCGCTGGCGTCATGGCTCTTCGGCCGGAGACAATACCTCTGTTCGCCAT
TCCTTTTTCCGGAAAATGCC

Downstream 100 bases:

>100_bases
GGCTCGTTCGGGAATAGGTTGTGCATTTGACCGTCGGATTCGGGATGCGCTGCTAGGCGCGGTGAGCGCCGTGTGGCCAG
GCCACACAAGCGAGTCGCAA

Product: type 12 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPDNYLPQVRSQYEALPYPPCNPEDDRQRLVLTWLEDLPMINHYCFAGKQSFRNGFRALVAGGGTGDATIFLAEQLRATD
AQIVHLDMSEASIALAKERARIRGLSNITWVHDSLLNLPHLGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGL
MVYATAGRTGVYQMQALMRLVNGTQADDQRKIANTRDLLASLPPSNWFKRSEDLHHDHKAGDAGIYDLLLHSQDRSYSVG
ELFDWLGHDAAGTGGHGLHLEFTDVQRGRSPYLPHMVLGSQPPAMAGELRKMPRRRQYEMAELMIGNLITHSLYVTRDAG
CTAPYGNAEYVPFFFHEPLTGDIAAQVFSSNRGQPFLLRHQHSGVSVMVNPGRYGPQILRLIDGQRTFGEIFDQFRADWR
GQAAAPDNAALFADFSESFDVLNALDRLLLKHPQADAAKAP

Sequences:

>Translated_441_residues
MPDNYLPQVRSQYEALPYPPCNPEDDRQRLVLTWLEDLPMINHYCFAGKQSFRNGFRALVAGGGTGDATIFLAEQLRATD
AQIVHLDMSEASIALAKERARIRGLSNITWVHDSLLNLPHLGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGL
MVYATAGRTGVYQMQALMRLVNGTQADDQRKIANTRDLLASLPPSNWFKRSEDLHHDHKAGDAGIYDLLLHSQDRSYSVG
ELFDWLGHDAAGTGGHGLHLEFTDVQRGRSPYLPHMVLGSQPPAMAGELRKMPRRRQYEMAELMIGNLITHSLYVTRDAG
CTAPYGNAEYVPFFFHEPLTGDIAAQVFSSNRGQPFLLRHQHSGVSVMVNPGRYGPQILRLIDGQRTFGEIFDQFRADWR
GQAAAPDNAALFADFSESFDVLNALDRLLLKHPQADAAKAP
>Mature_440_residues
PDNYLPQVRSQYEALPYPPCNPEDDRQRLVLTWLEDLPMINHYCFAGKQSFRNGFRALVAGGGTGDATIFLAEQLRATDA
QIVHLDMSEASIALAKERARIRGLSNITWVHDSLLNLPHLGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGLM
VYATAGRTGVYQMQALMRLVNGTQADDQRKIANTRDLLASLPPSNWFKRSEDLHHDHKAGDAGIYDLLLHSQDRSYSVGE
LFDWLGHDAAGTGGHGLHLEFTDVQRGRSPYLPHMVLGSQPPAMAGELRKMPRRRQYEMAELMIGNLITHSLYVTRDAGC
TAPYGNAEYVPFFFHEPLTGDIAAQVFSSNRGQPFLLRHQHSGVSVMVNPGRYGPQILRLIDGQRTFGEIFDQFRADWRG
QAAAPDNAALFADFSESFDVLNALDRLLLKHPQADAAKAP

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2067c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 49005; Mature: 48874

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDNYLPQVRSQYEALPYPPCNPEDDRQRLVLTWLEDLPMINHYCFAGKQSFRNGFRALV
CCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHEEEE
AGGGTGDATIFLAEQLRATDAQIVHLDMSEASIALAKERARIRGLSNITWVHDSLLNLPH
ECCCCCCEEEEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
LGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGLMVYATAGRTGVYQMQALMRL
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHH
VNGTQADDQRKIANTRDLLASLPPSNWFKRSEDLHHDHKAGDAGIYDLLLHSQDRSYSVG
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCCCHHHHHEECCCCCCCHH
ELFDWLGHDAAGTGGHGLHLEFTDVQRGRSPYLPHMVLGSQPPAMAGELRKMPRRRQYEM
HHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHH
AELMIGNLITHSLYVTRDAGCTAPYGNAEYVPFFFHEPLTGDIAAQVFSSNRGQPFLLRH
HHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEE
QHSGVSVMVNPGRYGPQILRLIDGQRTFGEIFDQFRADWRGQAAAPDNAALFADFSESFD
CCCCEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
VLNALDRLLLKHPQADAAKAP
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PDNYLPQVRSQYEALPYPPCNPEDDRQRLVLTWLEDLPMINHYCFAGKQSFRNGFRALV
CCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHEEEE
AGGGTGDATIFLAEQLRATDAQIVHLDMSEASIALAKERARIRGLSNITWVHDSLLNLPH
ECCCCCCEEEEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
LGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGLMVYATAGRTGVYQMQALMRL
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHH
VNGTQADDQRKIANTRDLLASLPPSNWFKRSEDLHHDHKAGDAGIYDLLLHSQDRSYSVG
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCCCHHHHHEECCCCCCCHH
ELFDWLGHDAAGTGGHGLHLEFTDVQRGRSPYLPHMVLGSQPPAMAGELRKMPRRRQYEM
HHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHH
AELMIGNLITHSLYVTRDAGCTAPYGNAEYVPFFFHEPLTGDIAAQVFSSNRGQPFLLRH
HHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEE
QHSGVSVMVNPGRYGPQILRLIDGQRTFGEIFDQFRADWRGQAAAPDNAALFADFSESFD
CCCCEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
VLNALDRLLLKHPQADAAKAP
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041005; 1901865 [H]