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The map label for this gene is iorA [H]

Identifier: 91790066

GI number: 91790066

Start: 4456373

End: 4456864

Strand: Reverse

Name: iorA [H]

Synonym: Bpro_4228

Alternate gene names: 91790066

Gene position: 4456864-4456373 (Counterclockwise)

Preceding gene: 91790069

Following gene: 91790065

Centisome position: 85.7

GC content: 65.85

Gene sequence:

>492_bases
GTGGAGTTACCGATCAAGCTGGACCTCAACGGCCGCGCTGTGCAGCTCGATGCCGACCCCGGCATGCCACTGCTCTGGCT
GCTGCGGGATGTGCTGAACCTGACCGGTACCAAGTTTGGCTGCGGCGTGGCGGCCTGCGGTGCCTGCACCGTGCGGGTGG
ATGGCCAGGCCGTGCGGTCCTGTATGACGCCTGTGTCGGCCGTGCTGGGCAAACGCGTGCAAACCATTGAAGCCCTGGGC
ACGCCCGACAAACCCCATGCCCTGCAACTGGCCTGGATCGCCGAGCAGGTGCCCCAGTGCGGTTATTGCCAGTCGGGCAT
GCTGATGGCAGCAGCCGCCCTGCTCGACAGGAAGCCCAAACCCACCGATGCCGACATTGACGCGGCCATGACCAATATCT
GCCGCTGCGGTACGTACCAGAGGATCCGGGCGGCCATCAAGCGGGCGGCGGGCATCGCGGCCAATGGTGGCTTGAAAAAG
GCCGGCCCATGA

Upstream 100 bases:

>100_bases
CGATTTGTCGGGGCTTCCCGGGCTTTGGTGGGCGAGGGCTGGCCACCGCATCGTCGCGTTATAGTGGTCCTGTCCTTGAT
GGACTTTCAGGAGACGCCGC

Downstream 100 bases:

>100_bases
AAAGACGCGCCTGGCTGCTGAGTGCGGCAGGGGCTGCGGGCGCGCTGGTCATCGGCTGGAGCGTGTTGCCACCGCGTTCC
CGGCTGGGCAGCGCCGGCTC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MELPIKLDLNGRAVQLDADPGMPLLWLLRDVLNLTGTKFGCGVAACGACTVRVDGQAVRSCMTPVSAVLGKRVQTIEALG
TPDKPHALQLAWIAEQVPQCGYCQSGMLMAAAALLDRKPKPTDADIDAAMTNICRCGTYQRIRAAIKRAAGIAANGGLKK
AGP

Sequences:

>Translated_163_residues
MELPIKLDLNGRAVQLDADPGMPLLWLLRDVLNLTGTKFGCGVAACGACTVRVDGQAVRSCMTPVSAVLGKRVQTIEALG
TPDKPHALQLAWIAEQVPQCGYCQSGMLMAAAALLDRKPKPTDADIDAAMTNICRCGTYQRIRAAIKRAAGIAANGGLKK
AGP
>Mature_163_residues
MELPIKLDLNGRAVQLDADPGMPLLWLLRDVLNLTGTKFGCGVAACGACTVRVDGQAVRSCMTPVSAVLGKRVQTIEALG
TPDKPHALQLAWIAEQVPQCGYCQSGMLMAAAALLDRKPKPTDADIDAAMTNICRCGTYQRIRAAIKRAAGIAANGGLKK
AGP

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=37.4149659863946, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=35.5263157894737, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=40.6060606060606, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=39.8601398601399, Blast_Score=92, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=163, Percent_Identity=39.2638036809816, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=37.6623376623377, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=37.5, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=31.0975609756098, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=31.0975609756098, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647199, Length=160, Percent_Identity=34.375, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17114; Mature: 17114

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPIKLDLNGRAVQLDADPGMPLLWLLRDVLNLTGTKFGCGVAACGACTVRVDGQAVRS
CCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHCCEEEEEECHHHHHH
CMTPVSAVLGKRVQTIEALGTPDKPHALQLAWIAEQVPQCGYCQSGMLMAAAALLDRKPK
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
PTDADIDAAMTNICRCGTYQRIRAAIKRAAGIAANGGLKKAGP
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MELPIKLDLNGRAVQLDADPGMPLLWLLRDVLNLTGTKFGCGVAACGACTVRVDGQAVRS
CCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHCCEEEEEECHHHHHH
CMTPVSAVLGKRVQTIEALGTPDKPHALQLAWIAEQVPQCGYCQSGMLMAAAALLDRKPK
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
PTDADIDAAMTNICRCGTYQRIRAAIKRAAGIAANGGLKKAGP
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]