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The map label for this gene is corC [H]

Identifier: 91790047

GI number: 91790047

Start: 4428523

End: 4429377

Strand: Reverse

Name: corC [H]

Synonym: Bpro_4209

Alternate gene names: 91790047

Gene position: 4429377-4428523 (Counterclockwise)

Preceding gene: 91790049

Following gene: 91790046

Centisome position: 85.18

GC content: 61.75

Gene sequence:

>855_bases
GTGTCCGACACCCCCCCCAGTCGATCTTCCAGGCCGGAAGACAAGCGCGGCTTTCTGCAGAAGCTGGCTGAAATGCTCCA
CCCCGGACCCGACTCCAAAGACGAGCTGATAGAAACCCTGGTCGAAGCCCAGGACAACGAAGTCATTGGCGCCCAGAGCC
GCGAAATGCTCGAAGGCGTGATCCGCATGGCCGATATGACGGCCGGTGACGTGATGGTGGCAGCGCCGCGCATGGATGTG
ATCAACATCGACGCGCCCTTTGACGAATTGCTGCATCTGGTGATTGACACCGCCCACTCGCGCTTTCCGGTCTACGAGGG
CGAGAAGGAAAACATTCTGGGCATCCTGATGGCCAAGGACCTGCTCAAGCTGCAGCGCGCGCCGGAGCTCAACATCAAGG
CGCTGCTGCGTCCGGCCGTGTTTGTGCCCGAAAGCAAGGGACTGAATGATTTGCTGCGCGAGTTCCGCGGCAACCGCAAC
CACCTGGCCATCGTCATCGACGAGTTCGGCCGTGTCGCCGGCCTCATCACGATTGAAGACGTGCTGGAGCAGATCGTGGG
CGAGATCGAGGACGAATTCGACATTGCCGAGGACGAAGGCGACATCTTCGGGCTCTCGGACCACACTTACCGGGTCAGCG
GCGACACCTCGATCGAACGCGTCAACGAGGCGTTTGGCGTCACGCTGCCCGAAACCGACTTCGAAACCATTGGCGGCCTG
GTGGCGCACGAGATGGGCCATGTGCCCAAGCGGGGCGAACATTACGCGCTCTCCGGCCTGCAATTCACGGTGCTGCACAC
CAAGGGTGGAGCCGTGCGCTGGTTCAAGGTGTCGCCTGTTGTGGCCAGGGCCTGA

Upstream 100 bases:

>100_bases
TTGGGACATGCCGTCAGCGGTGGATTGGCCTGATGCGCGGCGGCGTTGCGCCATGGAATTGCGCTATCCTTGGCAGCTTC
ACAACTACCGAACACCCTTC

Downstream 100 bases:

>100_bases
GCCCTCTGAAAAGAAAGGGACCGATGGAGCCGAGTTCAATCCAAAGCATGATGTCTGCGCTGCCGACCTTGCCGGCGCTG
CTGCAACACTTCGGTCAGAC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSDTPPSRSSRPEDKRGFLQKLAEMLHPGPDSKDELIETLVEAQDNEVIGAQSREMLEGVIRMADMTAGDVMVAAPRMDV
INIDAPFDELLHLVIDTAHSRFPVYEGEKENILGILMAKDLLKLQRAPELNIKALLRPAVFVPESKGLNDLLREFRGNRN
HLAIVIDEFGRVAGLITIEDVLEQIVGEIEDEFDIAEDEGDIFGLSDHTYRVSGDTSIERVNEAFGVTLPETDFETIGGL
VAHEMGHVPKRGEHYALSGLQFTVLHTKGGAVRWFKVSPVVARA

Sequences:

>Translated_284_residues
MSDTPPSRSSRPEDKRGFLQKLAEMLHPGPDSKDELIETLVEAQDNEVIGAQSREMLEGVIRMADMTAGDVMVAAPRMDV
INIDAPFDELLHLVIDTAHSRFPVYEGEKENILGILMAKDLLKLQRAPELNIKALLRPAVFVPESKGLNDLLREFRGNRN
HLAIVIDEFGRVAGLITIEDVLEQIVGEIEDEFDIAEDEGDIFGLSDHTYRVSGDTSIERVNEAFGVTLPETDFETIGGL
VAHEMGHVPKRGEHYALSGLQFTVLHTKGGAVRWFKVSPVVARA
>Mature_283_residues
SDTPPSRSSRPEDKRGFLQKLAEMLHPGPDSKDELIETLVEAQDNEVIGAQSREMLEGVIRMADMTAGDVMVAAPRMDVI
NIDAPFDELLHLVIDTAHSRFPVYEGEKENILGILMAKDLLKLQRAPELNIKALLRPAVFVPESKGLNDLLREFRGNRNH
LAIVIDEFGRVAGLITIEDVLEQIVGEIEDEFDIAEDEGDIFGLSDHTYRVSGDTSIERVNEAFGVTLPETDFETIGGLV
AHEMGHVPKRGEHYALSGLQFTVLHTKGGAVRWFKVSPVVARA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=218, Percent_Identity=30.7339449541284, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI94681046, Length=181, Percent_Identity=30.3867403314917, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40068055, Length=181, Percent_Identity=28.7292817679558, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40068053, Length=181, Percent_Identity=28.7292817679558, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786879, Length=267, Percent_Identity=44.9438202247191, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87082033, Length=249, Percent_Identity=28.5140562248996, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693175, Length=258, Percent_Identity=27.1317829457364, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788119, Length=219, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=27.9475982532751, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31446; Mature: 31315

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTPPSRSSRPEDKRGFLQKLAEMLHPGPDSKDELIETLVEAQDNEVIGAQSREMLEGV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHH
IRMADMTAGDVMVAAPRMDVINIDAPFDELLHLVIDTAHSRFPVYEGEKENILGILMAKD
HHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LLKLQRAPELNIKALLRPAVFVPESKGLNDLLREFRGNRNHLAIVIDEFGRVAGLITIED
HHHHHCCCCCCHHHHHCCCEECCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHEEEEHHH
VLEQIVGEIEDEFDIAEDEGDIFGLSDHTYRVSGDTSIERVNEAFGVTLPETDFETIGGL
HHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHH
VAHEMGHVPKRGEHYALSGLQFTVLHTKGGAVRWFKVSPVVARA
HHHHHCCCCCCCCEEEECCEEEEEEEECCCEEEEEEECCHHCCC
>Mature Secondary Structure 
SDTPPSRSSRPEDKRGFLQKLAEMLHPGPDSKDELIETLVEAQDNEVIGAQSREMLEGV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHH
IRMADMTAGDVMVAAPRMDVINIDAPFDELLHLVIDTAHSRFPVYEGEKENILGILMAKD
HHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LLKLQRAPELNIKALLRPAVFVPESKGLNDLLREFRGNRNHLAIVIDEFGRVAGLITIED
HHHHHCCCCCCHHHHHCCCEECCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHEEEEHHH
VLEQIVGEIEDEFDIAEDEGDIFGLSDHTYRVSGDTSIERVNEAFGVTLPETDFETIGGL
HHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHH
VAHEMGHVPKRGEHYALSGLQFTVLHTKGGAVRWFKVSPVVARA
HHHHHCCCCCCCCEEEECCEEEEEEEECCCEEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]