Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 91789989

GI number: 91789989

Start: 4363869

End: 4366058

Strand: Direct

Name: dnaQ [H]

Synonym: Bpro_4151

Alternate gene names: 91789989

Gene position: 4363869-4366058 (Clockwise)

Preceding gene: 91789988

Following gene: 91789990

Centisome position: 83.92

GC content: 63.74

Gene sequence:

>2190_bases
ATGACCCCTCGAATCCGGCTCGCTGTGGGACTCGGCGGTCTGTATGGACTGCTGGTCGTGCTCTTTGGCATCCTGGGTGC
GGTGCTGTGGGCCGACATGCGGGACGCCGAGCGGCTGGCGGTGCTGGCCATCATGCGGGAGCGTTACGCGCTGGCCTTGG
TCATCATCCTGCTGGCCTGGATCGGGCTGGGGCTGCTGGCCTGGGGTCTGTTCCGGATCTATGTGCTGGCCCCTTTGAGC
CTGCGTGAACAGGCCCTGGTGATGGTCAATTCCAACCCGGCGCTGCGACTGCAAGAGCTCGGCGCCCCCGAGATCCGGAC
GCTGGTGCAGGTCGTCAATACACTGGCCGACCAGCGCGAATCGCTGCTGCGCGATGTAGAGCAGAAAATCCTGCAAGCCA
AGGCCTCGGTCGAGGAGGAAAAAAACCGTCTGGCCGCGTTGATGTCGGAACTCACGCAAAGCGTGGTCGTGTGCAACCTG
GATGGACGCATCCTGCTCTACAACAACCGTGCGCGCCTGCAGTTTCAGGTGCCTGGAGATGGCGCGCAAGGTGGCAGCGC
AGCCTTGATCGGCCTGGGCCGTTCCATTTTTGCCCTCATGGAACGCGGTCTCATCACGCACGCCCTGGAGCGCGTGCAGC
ACCGCCTCAGGCACGGCAGCGCACAGCCCTCAGCCAACTTCGTCACCACCACGCGCACCGGGCAACTGATACGCGTTCAA
ATGGCCCCGGTCTTCAGCAACGCCTGGCGCGATAACGACGCGCAGGACCGCGCCACCGGGGAGCGGGTCATCAGCGGCTA
CGTGCTCCTGCTCGATAACATCACCCGCAATGTGGAAACGCAAAGCCGGCGCGACCTGCTCCTGCAAACGCTCACCGAAG
GCAGCCGCGCCGCGTTGGGAAATATACGGGCGGCGGTAGAAAACCTGCTGCAATACCCGGACATGGAGATCGGCCAGCGC
GACCGCTTCGTGGGCGTGATCCGCGACGAAGCGGAGGCCATGAGCCAACGCATCAACCACGCCAGCGCCGAGTTCGCCGA
CACACTCAAGGCGCGCTGGCCGCTGGAAGACATGCATGGCGCAGACCTGGTGCAGGCCTTGCAGCGACGCATTGAACAAA
AGTCCGGTTTGAGCGCCAGCAGCGAAGAGGTCGCCAGCGGCCTGTGGGTCAAGGTGGACAGCTACTCGTTGCTGCAGGGC
CTGAGCTACCTCGCCGCCCGGCTCAGGGATGAGTGCGGCGTGGGCGCCGTGACCTTGCGTCTGCGGCCGTCCGGGCGGCT
GGCACAGCTGGACCTGCTCTGGTCGGGCGCCGCCCTGGACGCGGCGATGCTGGCGAACTGGGAACAGTCCCCGATGAACT
CTGACGGCGAAGGCATCCCATTGACGCTGCGCGAAGTGATCGAACGCCATGGCGGCGAACTCTGGCACCAGCGCGACCAG
AATACGCAGCAACCCCTGATCCGGATGCTGCTGCCCACCGCCGCGGCGCAGGATGCGGCCGACCCGGCCGTATGGCTGCG
CCATGAGAGCCGCCCCGAGTACTACGACTTTGACCTGTTCAAGCAAACCGAGGAGACACGTGCGCTGGATGATCGCCTGC
TGACGCAACTGAGCTACACGGTGTTTGACACCGAGACCACCGGACTGGAGCCTTCGGCCGGCGATGAGATCATCCAGATT
GGCGCCATCCGCATCGTCAACGGTCGCTTGCTCAGGAACGAGACCATCGACCAGCTGATTGATCCCAGGCGGCGGCTCAA
GCCCGAATCCATTGCCATCCACGGCATCACCGAAGACATGGTCAAAGGGCAACCGACGATTGAGCAGGCTCTTCCCGCCT
TTCATGAATTCTGCGAGGACACGGTGCTGGTGGCGCACAACGCCGCGTTTGACATGCGTTTCCTGCAGCTCAAGGAGGCA
TCCACCGGCATCGTGTTCCGGCAACCGGTGCTGGACACCTTGCTGCTGTCGGCGCTGCTTCATCCCAACCAGGAATCACA
CCGCCTGGAGGCCATTGCCGGGCGCCTGGGCATCAACGTGATCGGGCGCCATACGGCCCTGGGCGATGCGATCGTTACCG
GAGAGATTTTCCTCAAGATGATTCCCTTGCTGGCGCAACAGAACATTCACACCTTGCGCCAGGCACGCGAGGCGGCCGCG
CGCACCTATTACGCCAGAGTCAGTTACTAA

Upstream 100 bases:

>100_bases
CACCAAGGATCTGGTTGCACAGGTGCGTCAACTGCTCGGACTGCCAGTGCAGTAGCCGTCCATTGGTCGACGTGCCCGCC
CAACCCATTGCCCAGCCGCC

Downstream 100 bases:

>100_bases
AGGTGACATCATGGAGCCAGCCCCAGACCCCGACCCGCGCCATGATTTCCAGGCCATGCACAGCCCGCTGAGTCAGATTG
CACGGCGCGAGCCGGTGACA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MTPRIRLAVGLGGLYGLLVVLFGILGAVLWADMRDAERLAVLAIMRERYALALVIILLAWIGLGLLAWGLFRIYVLAPLS
LREQALVMVNSNPALRLQELGAPEIRTLVQVVNTLADQRESLLRDVEQKILQAKASVEEEKNRLAALMSELTQSVVVCNL
DGRILLYNNRARLQFQVPGDGAQGGSAALIGLGRSIFALMERGLITHALERVQHRLRHGSAQPSANFVTTTRTGQLIRVQ
MAPVFSNAWRDNDAQDRATGERVISGYVLLLDNITRNVETQSRRDLLLQTLTEGSRAALGNIRAAVENLLQYPDMEIGQR
DRFVGVIRDEAEAMSQRINHASAEFADTLKARWPLEDMHGADLVQALQRRIEQKSGLSASSEEVASGLWVKVDSYSLLQG
LSYLAARLRDECGVGAVTLRLRPSGRLAQLDLLWSGAALDAAMLANWEQSPMNSDGEGIPLTLREVIERHGGELWHQRDQ
NTQQPLIRMLLPTAAAQDAADPAVWLRHESRPEYYDFDLFKQTEETRALDDRLLTQLSYTVFDTETTGLEPSAGDEIIQI
GAIRIVNGRLLRNETIDQLIDPRRRLKPESIAIHGITEDMVKGQPTIEQALPAFHEFCEDTVLVAHNAAFDMRFLQLKEA
STGIVFRQPVLDTLLLSALLHPNQESHRLEAIAGRLGINVIGRHTALGDAIVTGEIFLKMIPLLAQQNIHTLRQAREAAA
RTYYARVSY

Sequences:

>Translated_729_residues
MTPRIRLAVGLGGLYGLLVVLFGILGAVLWADMRDAERLAVLAIMRERYALALVIILLAWIGLGLLAWGLFRIYVLAPLS
LREQALVMVNSNPALRLQELGAPEIRTLVQVVNTLADQRESLLRDVEQKILQAKASVEEEKNRLAALMSELTQSVVVCNL
DGRILLYNNRARLQFQVPGDGAQGGSAALIGLGRSIFALMERGLITHALERVQHRLRHGSAQPSANFVTTTRTGQLIRVQ
MAPVFSNAWRDNDAQDRATGERVISGYVLLLDNITRNVETQSRRDLLLQTLTEGSRAALGNIRAAVENLLQYPDMEIGQR
DRFVGVIRDEAEAMSQRINHASAEFADTLKARWPLEDMHGADLVQALQRRIEQKSGLSASSEEVASGLWVKVDSYSLLQG
LSYLAARLRDECGVGAVTLRLRPSGRLAQLDLLWSGAALDAAMLANWEQSPMNSDGEGIPLTLREVIERHGGELWHQRDQ
NTQQPLIRMLLPTAAAQDAADPAVWLRHESRPEYYDFDLFKQTEETRALDDRLLTQLSYTVFDTETTGLEPSAGDEIIQI
GAIRIVNGRLLRNETIDQLIDPRRRLKPESIAIHGITEDMVKGQPTIEQALPAFHEFCEDTVLVAHNAAFDMRFLQLKEA
STGIVFRQPVLDTLLLSALLHPNQESHRLEAIAGRLGINVIGRHTALGDAIVTGEIFLKMIPLLAQQNIHTLRQAREAAA
RTYYARVSY
>Mature_728_residues
TPRIRLAVGLGGLYGLLVVLFGILGAVLWADMRDAERLAVLAIMRERYALALVIILLAWIGLGLLAWGLFRIYVLAPLSL
REQALVMVNSNPALRLQELGAPEIRTLVQVVNTLADQRESLLRDVEQKILQAKASVEEEKNRLAALMSELTQSVVVCNLD
GRILLYNNRARLQFQVPGDGAQGGSAALIGLGRSIFALMERGLITHALERVQHRLRHGSAQPSANFVTTTRTGQLIRVQM
APVFSNAWRDNDAQDRATGERVISGYVLLLDNITRNVETQSRRDLLLQTLTEGSRAALGNIRAAVENLLQYPDMEIGQRD
RFVGVIRDEAEAMSQRINHASAEFADTLKARWPLEDMHGADLVQALQRRIEQKSGLSASSEEVASGLWVKVDSYSLLQGL
SYLAARLRDECGVGAVTLRLRPSGRLAQLDLLWSGAALDAAMLANWEQSPMNSDGEGIPLTLREVIERHGGELWHQRDQN
TQQPLIRMLLPTAAAQDAADPAVWLRHESRPEYYDFDLFKQTEETRALDDRLLTQLSYTVFDTETTGLEPSAGDEIIQIG
AIRIVNGRLLRNETIDQLIDPRRRLKPESIAIHGITEDMVKGQPTIEQALPAFHEFCEDTVLVAHNAAFDMRFLQLKEAS
TGIVFRQPVLDTLLLSALLHPNQESHRLEAIAGRLGINVIGRHTALGDAIVTGEIFLKMIPLLAQQNIHTLRQAREAAAR
TYYARVSY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=171, Percent_Identity=32.7485380116959, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 81049; Mature: 80918

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRIRLAVGLGGLYGLLVVLFGILGAVLWADMRDAERLAVLAIMRERYALALVIILLAW
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLGLLAWGLFRIYVLAPLSLREQALVMVNSNPALRLQELGAPEIRTLVQVVNTLADQRE
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHCCCHHHHHHHHHHHHHHHHHH
SLLRDVEQKILQAKASVEEEKNRLAALMSELTQSVVVCNLDGRILLYNNRARLQFQVPGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCEEEEEECCCC
GAQGGSAALIGLGRSIFALMERGLITHALERVQHRLRHGSAQPSANFVTTTRTGQLIRVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
MAPVFSNAWRDNDAQDRATGERVISGYVLLLDNITRNVETQSRRDLLLQTLTEGSRAALG
ECHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
NIRAAVENLLQYPDMEIGQRDRFVGVIRDEAEAMSQRINHASAEFADTLKARWPLEDMHG
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
ADLVQALQRRIEQKSGLSASSEEVASGLWVKVDSYSLLQGLSYLAARLRDECGVGAVTLR
HHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
LRPSGRLAQLDLLWSGAALDAAMLANWEQSPMNSDGEGIPLTLREVIERHGGELWHQRDQ
ECCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCC
NTQQPLIRMLLPTAAAQDAADPAVWLRHESRPEYYDFDLFKQTEETRALDDRLLTQLSYT
CHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFDTETTGLEPSAGDEIIQIGAIRIVNGRLLRNETIDQLIDPRRRLKPESIAIHGITEDM
EEECCCCCCCCCCCCCEEEECEEEEECCCHHHHHHHHHHHCHHHHCCCCCEEEECCHHHH
VKGQPTIEQALPAFHEFCEDTVLVAHNAAFDMRFLQLKEASTGIVFRQPVLDTLLLSALL
HCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
HPNQESHRLEAIAGRLGINVIGRHTALGDAIVTGEIFLKMIPLLAQQNIHTLRQAREAAA
CCCCHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTYYARVSY
HHHHEEECC
>Mature Secondary Structure 
TPRIRLAVGLGGLYGLLVVLFGILGAVLWADMRDAERLAVLAIMRERYALALVIILLAW
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLGLLAWGLFRIYVLAPLSLREQALVMVNSNPALRLQELGAPEIRTLVQVVNTLADQRE
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHCCCHHHHHHHHHHHHHHHHHH
SLLRDVEQKILQAKASVEEEKNRLAALMSELTQSVVVCNLDGRILLYNNRARLQFQVPGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCEEEEEECCCC
GAQGGSAALIGLGRSIFALMERGLITHALERVQHRLRHGSAQPSANFVTTTRTGQLIRVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
MAPVFSNAWRDNDAQDRATGERVISGYVLLLDNITRNVETQSRRDLLLQTLTEGSRAALG
ECHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
NIRAAVENLLQYPDMEIGQRDRFVGVIRDEAEAMSQRINHASAEFADTLKARWPLEDMHG
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
ADLVQALQRRIEQKSGLSASSEEVASGLWVKVDSYSLLQGLSYLAARLRDECGVGAVTLR
HHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
LRPSGRLAQLDLLWSGAALDAAMLANWEQSPMNSDGEGIPLTLREVIERHGGELWHQRDQ
ECCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCC
NTQQPLIRMLLPTAAAQDAADPAVWLRHESRPEYYDFDLFKQTEETRALDDRLLTQLSYT
CHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFDTETTGLEPSAGDEIIQIGAIRIVNGRLLRNETIDQLIDPRRRLKPESIAIHGITEDM
EEECCCCCCCCCCCCCEEEECEEEEECCCHHHHHHHHHHHCHHHHCCCCCEEEECCHHHH
VKGQPTIEQALPAFHEFCEDTVLVAHNAAFDMRFLQLKEASTGIVFRQPVLDTLLLSALL
HCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
HPNQESHRLEAIAGRLGINVIGRHTALGDAIVTGEIFLKMIPLLAQQNIHTLRQAREAAA
CCCCHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTYYARVSY
HHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]