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The map label for this gene is ruvA

Identifier: 91789933

GI number: 91789933

Start: 4303229

End: 4303801

Strand: Reverse

Name: ruvA

Synonym: Bpro_4094

Alternate gene names: 91789933

Gene position: 4303801-4303229 (Counterclockwise)

Preceding gene: 91789936

Following gene: 91789932

Centisome position: 82.76

GC content: 63.18

Gene sequence:

>573_bases
ATGATCGGAAGAATCTCAGGCCAGCTGGCCGAAAAAAATCCACCGGAAGTCCTGGTGGACTGCAACGGCGTCGGCTATGA
GGTGCTGGTGCCCATGAGCACCTTTTATAACCTGCCCGGGCTGGGCGAAAAAGTCAGCCTGCTGACCCATTTTGTGGTGC
GCGAGGACGCGCAAATCCTCTACGGTTTTGGCAGCGCCACCGAGCGCGCCGCGTTCCGCCAGCTCATCAAGATTTCGGGC
GTCGGCCCGCGCACCGCGCTGAGTGTGCTGAGCGGCATGAGCGTCGAGGAGCTTGCCCAGGCCGTGACTCACCAGGAGGC
CGGCCGCATCATCAAGGTGCCCGGCATCGGCAAGAAAACCGCCGAACGGCTGCTGCTGGAGCTCAAGGGCAAGCTGGGCG
CCGACATCGGCGTGCAGGTTAGTGTCAGCAGCGACAGCCAGTCCGACATCCTGCAGGCACTCGTGGCGCTGGGCTACAGC
GACCGCGATGCGGCGCTGGCGCTGAAAGCCTTGCCCAAGGATATCGGCGTCAGCGATGGCATCAAGCTGGCGCTGAAGGC
TCTGGCGAAATGA

Upstream 100 bases:

>100_bases
GTGTAGCGAAGGATCAAGGCGCGGCTTTTTCTGAAAGGGTGGGTTCTCGCGAGATTGTCCCCCCAAATTTCCGCGCCTGC
CTGACTGATAAGATTTGGCC

Downstream 100 bases:

>100_bases
TGTTTCTCCTGATGGTTCTTATTTCTCAAAAAAGCGCCGGGCCGCCCCAAGCTTTTTTGCTGGGTTGCCCACGCCAAAGT
ATCGTGGGAGCGCAGCGACC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQILYGFGSATERAAFRQLIKISG
VGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKTAERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYS
DRDAALALKALPKDIGVSDGIKLALKALAK

Sequences:

>Translated_190_residues
MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQILYGFGSATERAAFRQLIKISG
VGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKTAERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYS
DRDAALALKALPKDIGVSDGIKLALKALAK
>Mature_190_residues
MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQILYGFGSATERAAFRQLIKISG
VGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKTAERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYS
DRDAALALKALPKDIGVSDGIKLALKALAK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=44.7761194029851, Blast_Score=173, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_POLSJ (Q124Q5)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550885.1
- ProteinModelPortal:   Q124Q5
- SMR:   Q124Q5
- STRING:   Q124Q5
- GeneID:   4013227
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4094
- NMPDR:   fig|296591.1.peg.4161
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q124Q5
- ProtClustDB:   PRK00116
- BioCyc:   PSP296591:BPRO_4094-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20010; Mature: 20010

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQIL
CCCCCCCCCCCCCCCCEEEECCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCEE
YGFGSATERAAFRQLIKISGVGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKT
EECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYSDRDAALALKALPKDIGVSDG
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
IKLALKALAK
HHHHHHHHCC
>Mature Secondary Structure
MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQIL
CCCCCCCCCCCCCCCCEEEECCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCEE
YGFGSATERAAFRQLIKISGVGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKT
EECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYSDRDAALALKALPKDIGVSDG
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
IKLALKALAK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA