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The map label for this gene is ruvB

Identifier: 91789932

GI number: 91789932

Start: 4302043

End: 4303107

Strand: Reverse

Name: ruvB

Synonym: Bpro_4093

Alternate gene names: 91789932

Gene position: 4303107-4302043 (Counterclockwise)

Preceding gene: 91789933

Following gene: 91789925

Centisome position: 82.75

GC content: 64.41

Gene sequence:

>1065_bases
ATGAGCATTCAGACCGACGATTTCTCCGCAGCCGATCTGCCGCCCGTCAAGCGCGTGATGTCGGCCGCGCCCGCTTCGCC
CCATGAGGAAGCGATCGAGCGCGCGCTGCGGCCCAAGCTGTTTGACGAGTACGTTGGCCAGGCCAAGGTGCGCGAGCAGC
TCGAGATTTTCATTGGCGCGGCCAAGAAGCGCAGTGAAGCACTCGACCATGTGCTGCTGTTCGGCCCGCCGGGCCTGGGC
AAGACCACGCTGTCGCACATCATTGCGCATGAGCTGGGCGTCAATCTGCGCCAGACCTCGGGCCCGGTGCTCGAAAAACC
CAAGGACCTGGCGGCGCTGCTGACCAACCTGGAAAAAAACGACGTCCTCTTCATCGACGAAATCCACCGCCTGAGCCCGG
TGGTCGAGGAAATCCTCTACCCGGCGCTGGAGGACTACCAGATCGACATCATGATTGGTGAAGGTCCCGCGGCGCGCAGC
ATCAAGCTCGACCTGCAGCCCTTCACGCTGGTAGGCGCCACCACGCGCGCCGGCATGCTGACCAACCCCTTGCGCGACCG
TTTCGGCATCGTCGCGCGGCTGGAGTTCTACACCGCCGAGGAGCTCGGGCGCATCGTCAGGCGCAGCGCCAGCCTGCTCA
ATGCGCCGATGGATGAGGAGGGCGGTTTTGAGATTGCACGCCGCTCACGCGGTACGCCGCGCATTGCCAACCGCCTGCTG
CGCCGCGTGCGCGACTATGCCGACGTCAAGGGCACGGGCCAGATCACCCTGGACATTGCCAACAAGGCCCTGGCCATGCT
CGATGTGGACCCGCAGGGTTTTGACGTGATGGACCGCAAGCTACTCGAAGCCGTGATCCACCGCTTTGACGGTGGCCCGG
TCGGGCTGGACAACATCGCCGCCAGCATTGGCGAAGAACGCGACACGATTGAAGATGTGATCGAGCCCTACCTGATCCAG
CAGGGCTATCTGCAGCGAACGCCGCGCGGCCGCATTGCCACGCTGGCAGCCTACCGCCACCTCGGTGTGGCGCCCCCGGT
GAGCGGCAACGACATGTTTACCTGA

Upstream 100 bases:

>100_bases
TTTCTCAAAAAAGCGCCGGGCCGCCCCAAGCTTTTTTGCTGGGTTGCCCACGCCAAAGTATCGTGGGAGCGCAGCGACCG
AAACTTTGGTGTGAAACATC

Downstream 100 bases:

>100_bases
CGGCGCTGCATGGGCGGCTGGCGCGCTTTGGCGTGCAGGTTCGCTACTCGCCGCCAGGCCTCGTTGGTGAGCCTCGACGC
TCAGGTCAGTGCGCCCCGCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSIQTDDFSAADLPPVKRVMSAAPASPHEEAIERALRPKLFDEYVGQAKVREQLEIFIGAAKKRSEALDHVLLFGPPGLG
KTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARS
IKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTAEELGRIVRRSASLLNAPMDEEGGFEIARRSRGTPRIANRLL
RRVRDYADVKGTGQITLDIANKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEERDTIEDVIEPYLIQ
QGYLQRTPRGRIATLAAYRHLGVAPPVSGNDMFT

Sequences:

>Translated_354_residues
MSIQTDDFSAADLPPVKRVMSAAPASPHEEAIERALRPKLFDEYVGQAKVREQLEIFIGAAKKRSEALDHVLLFGPPGLG
KTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARS
IKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTAEELGRIVRRSASLLNAPMDEEGGFEIARRSRGTPRIANRLL
RRVRDYADVKGTGQITLDIANKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEERDTIEDVIEPYLIQ
QGYLQRTPRGRIATLAAYRHLGVAPPVSGNDMFT
>Mature_353_residues
SIQTDDFSAADLPPVKRVMSAAPASPHEEAIERALRPKLFDEYVGQAKVREQLEIFIGAAKKRSEALDHVLLFGPPGLGK
TTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSI
KLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTAEELGRIVRRSASLLNAPMDEEGGFEIARRSRGTPRIANRLLR
RVRDYADVKGTGQITLDIANKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEERDTIEDVIEPYLIQQ
GYLQRTPRGRIATLAAYRHLGVAPPVSGNDMFT

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=329, Percent_Identity=71.1246200607903, Blast_Score=475, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_POLSJ (Q124Q6)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550884.1
- ProteinModelPortal:   Q124Q6
- SMR:   Q124Q6
- STRING:   Q124Q6
- GeneID:   4013226
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4093
- NMPDR:   fig|296591.1.peg.4159
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q124Q6
- ProtClustDB:   PRK00080
- BioCyc:   PSP296591:BPRO_4093-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 39058; Mature: 38927

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQTDDFSAADLPPVKRVMSAAPASPHEEAIERALRPKLFDEYVGQAKVREQLEIFIGA
CCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AKKRSEALDHVLLFGPPGLGKTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKN
HHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCC
DVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGML
CEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHH
TNPLRDRFGIVARLEFYTAEELGRIVRRSASLLNAPMDEEGGFEIARRSRGTPRIANRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHH
RRVRDYADVKGTGQITLDIANKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNIA
HHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
ASIGEERDTIEDVIEPYLIQQGYLQRTPRGRIATLAAYRHLGVAPPVSGNDMFT
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIQTDDFSAADLPPVKRVMSAAPASPHEEAIERALRPKLFDEYVGQAKVREQLEIFIGA
CCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AKKRSEALDHVLLFGPPGLGKTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKN
HHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCC
DVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGML
CEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHH
TNPLRDRFGIVARLEFYTAEELGRIVRRSASLLNAPMDEEGGFEIARRSRGTPRIANRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHH
RRVRDYADVKGTGQITLDIANKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNIA
HHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
ASIGEERDTIEDVIEPYLIQQGYLQRTPRGRIATLAAYRHLGVAPPVSGNDMFT
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA