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The map label for this gene is xanB [H]

Identifier: 91789839

GI number: 91789839

Start: 4195710

End: 4197140

Strand: Direct

Name: xanB [H]

Synonym: Bpro_3999

Alternate gene names: 91789839

Gene position: 4195710-4197140 (Clockwise)

Preceding gene: 91789818

Following gene: 91789840

Centisome position: 80.68

GC content: 61.15

Gene sequence:

>1431_bases
ATGAAACTAGTTTCTATCATTCTTTCAGGGGGTGCAGGTACCCGATTGTGGCCGGTATCGCGCCAGGCGCTGCCCAAGCC
CTTCATGCATCTCGGCGGCAGCTCTTTGCTGCAGCAGGCCATTGAGCGGGGCCAGGCTTGCGGCACCGATGACAGCGTCA
TTGTGACCAATCAGGATTATCTGTTTCTGACGCGCAATGTCATCAAGCAACTGAGCGACCCGCCCAACGCCCGCTACCTT
CTTGAGCCCAAAGGCCGCAACACCGCACCCGCCATCGCCCTGGCCGCCCTGGCCTGCACGCAGGAGCACGGGCCTGAAGC
CGTCATGCTGGTGCTGCCCGCCGACCATTTGATTCCCGACACAGAGGCCTTTGTGGCCAGCGCGCTGGAGGCTGCACGGC
AGGCACTGCAGGGCCAACTGGTGGTGTTTGGCATTTCACCCACCGCGCCAGAAACCGGGTTTGGCTATATCGAAGTAGAA
AAAGTCAGCCGCCACACCCAGAAAGCCCTGCGTTTTGTAGAAAAGCCCGACCTGGCCACCGCACAGGGCTACCTGGCCAC
CGGCCGGTATTACTGGAACAGCGGCATGTTCTGCTTTACCGCGGGTACCATCCTGCAAGCACTCAAGGAGCACGCCCCCG
AGGTGCTGGAGGCGGCAGAACACGCCTGGACCACCAGCAGCACGGAAAGTGGCGCCACCCAGTTTGACGCCCATGCCTTT
GGCCTGCAGCCCGACATCAGCATTGACTACGCCGTGATGGAGCGCGCCAGCAACGTGACCCTGGTGCCCGCCAAATTTGG
CTGGAGCGACGTAGGCACCTGGCCCGCGGTGGCCCAGGCTTACACAGCTGACACCAGTGGCAACACCTTTGTAGACGGCG
AAGGCACGCAGTTCATCACGGTAGACACCACCGGCACCCACGTGCAAACAGACAGCCATACCGCCAAAGTAGTGGCCACT
GTAGGTGTGCACGACCTGGTGATCGTGGACACGCCCGATGCCCTGCTGATCGCCCACAAAAGCGCAGCGCAAAAAGTCAA
GGCCGTGGTTGACACGCTGAAGGAGCGCAAACACGAAAGCACTCAGCTGCCCGCTTCGGTCAATCGCCCTTGGGGCACTT
ACGCCACACTGAAAGAAGAAAGTGGCTACAAGGTCAAGCGCATCACGGTCAACCCGGGGCAATCGCTGAGCCTGCAGTAC
CACCACCAACGCGCCGAGCACTGGGTGGTGGTGCAAGGCACCGCCATCGTGCAGGTGGGCGATGAGGAGCACACCACCCT
GCCCGGCCAGTACCGCTACATTCCTCTCAAGGAAAAGCACCGCTTGACCAACACCGGCGAAAATGAGCTGGTTCTGATAG
AAGTGCAGTGCGGCGGCTACCTGGGCGAAGACGACATCGTGCGATTAGCTGACACCTACGGGCGCGCCTGA

Upstream 100 bases:

>100_bases
GCACCATGTAACTAATGCCGCGCCACATGTGTCAGATTGTTAGAACTACGCAATGCCCCCATGTAAAATCATTCCCCTTA
CAACAAGAGCTTAAGCAGGG

Downstream 100 bases:

>100_bases
AAACATGGAATGATTGCCGCCGATCAAACGTAATCGAATGTCACAATTGGGCGTTAGCTTCGACAAAATGTAAATGTATT
GGTGAATAGATTAATGATCA

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKLVSIILSGGAGTRLWPVSRQALPKPFMHLGGSSLLQQAIERGQACGTDDSVIVTNQDYLFLTRNVIKQLSDPPNARYL
LEPKGRNTAPAIALAALACTQEHGPEAVMLVLPADHLIPDTEAFVASALEAARQALQGQLVVFGISPTAPETGFGYIEVE
KVSRHTQKALRFVEKPDLATAQGYLATGRYYWNSGMFCFTAGTILQALKEHAPEVLEAAEHAWTTSSTESGATQFDAHAF
GLQPDISIDYAVMERASNVTLVPAKFGWSDVGTWPAVAQAYTADTSGNTFVDGEGTQFITVDTTGTHVQTDSHTAKVVAT
VGVHDLVIVDTPDALLIAHKSAAQKVKAVVDTLKERKHESTQLPASVNRPWGTYATLKEESGYKVKRITVNPGQSLSLQY
HHQRAEHWVVVQGTAIVQVGDEEHTTLPGQYRYIPLKEKHRLTNTGENELVLIEVQCGGYLGEDDIVRLADTYGRA

Sequences:

>Translated_476_residues
MKLVSIILSGGAGTRLWPVSRQALPKPFMHLGGSSLLQQAIERGQACGTDDSVIVTNQDYLFLTRNVIKQLSDPPNARYL
LEPKGRNTAPAIALAALACTQEHGPEAVMLVLPADHLIPDTEAFVASALEAARQALQGQLVVFGISPTAPETGFGYIEVE
KVSRHTQKALRFVEKPDLATAQGYLATGRYYWNSGMFCFTAGTILQALKEHAPEVLEAAEHAWTTSSTESGATQFDAHAF
GLQPDISIDYAVMERASNVTLVPAKFGWSDVGTWPAVAQAYTADTSGNTFVDGEGTQFITVDTTGTHVQTDSHTAKVVAT
VGVHDLVIVDTPDALLIAHKSAAQKVKAVVDTLKERKHESTQLPASVNRPWGTYATLKEESGYKVKRITVNPGQSLSLQY
HHQRAEHWVVVQGTAIVQVGDEEHTTLPGQYRYIPLKEKHRLTNTGENELVLIEVQCGGYLGEDDIVRLADTYGRA
>Mature_476_residues
MKLVSIILSGGAGTRLWPVSRQALPKPFMHLGGSSLLQQAIERGQACGTDDSVIVTNQDYLFLTRNVIKQLSDPPNARYL
LEPKGRNTAPAIALAALACTQEHGPEAVMLVLPADHLIPDTEAFVASALEAARQALQGQLVVFGISPTAPETGFGYIEVE
KVSRHTQKALRFVEKPDLATAQGYLATGRYYWNSGMFCFTAGTILQALKEHAPEVLEAAEHAWTTSSTESGATQFDAHAF
GLQPDISIDYAVMERASNVTLVPAKFGWSDVGTWPAVAQAYTADTSGNTFVDGEGTQFITVDTTGTHVQTDSHTAKVVAT
VGVHDLVIVDTPDALLIAHKSAAQKVKAVVDTLKERKHESTQLPASVNRPWGTYATLKEESGYKVKRITVNPGQSLSLQY
HHQRAEHWVVVQGTAIVQVGDEEHTTLPGQYRYIPLKEKHRLTNTGENELVLIEVQCGGYLGEDDIVRLADTYGRA

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=482, Percent_Identity=44.6058091286307, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51649; Mature: 51649

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVSIILSGGAGTRLWPVSRQALPKPFMHLGGSSLLQQAIERGQACGTDDSVIVTNQDY
CCEEEEEEECCCCCEEEECCHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCE
LFLTRNVIKQLSDPPNARYLLEPKGRNTAPAIALAALACTQEHGPEAVMLVLPADHLIPD
EEEEHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TEAFVASALEAARQALQGQLVVFGISPTAPETGFGYIEVEKVSRHTQKALRFVEKPDLAT
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
AQGYLATGRYYWNSGMFCFTAGTILQALKEHAPEVLEAAEHAWTTSSTESGATQFDAHAF
CCCEEEECEEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCEEE
GLQPDISIDYAVMERASNVTLVPAKFGWSDVGTWPAVAQAYTADTSGNTFVDGEGTQFIT
CCCCCCCEEHHHHHCCCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCEEECCCCCEEEE
VDTTGTHVQTDSHTAKVVATVGVHDLVIVDTPDALLIAHKSAAQKVKAVVDTLKERKHES
EECCCCEEECCCCCEEEEEEECCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCC
TQLPASVNRPWGTYATLKEESGYKVKRITVNPGQSLSLQYHHQRAEHWVVVQGTAIVQVG
CCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECEEEEEEC
DEEHTTLPGQYRYIPLKEKHRLTNTGENELVLIEVQCGGYLGEDDIVRLADTYGRA
CCCCCCCCCCEEEEECHHCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEHHHCCCC
>Mature Secondary Structure
MKLVSIILSGGAGTRLWPVSRQALPKPFMHLGGSSLLQQAIERGQACGTDDSVIVTNQDY
CCEEEEEEECCCCCEEEECCHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCE
LFLTRNVIKQLSDPPNARYLLEPKGRNTAPAIALAALACTQEHGPEAVMLVLPADHLIPD
EEEEHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TEAFVASALEAARQALQGQLVVFGISPTAPETGFGYIEVEKVSRHTQKALRFVEKPDLAT
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
AQGYLATGRYYWNSGMFCFTAGTILQALKEHAPEVLEAAEHAWTTSSTESGATQFDAHAF
CCCEEEECEEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCEEE
GLQPDISIDYAVMERASNVTLVPAKFGWSDVGTWPAVAQAYTADTSGNTFVDGEGTQFIT
CCCCCCCEEHHHHHCCCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCEEECCCCCEEEE
VDTTGTHVQTDSHTAKVVATVGVHDLVIVDTPDALLIAHKSAAQKVKAVVDTLKERKHES
EECCCCEEECCCCCEEEEEEECCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCC
TQLPASVNRPWGTYATLKEESGYKVKRITVNPGQSLSLQYHHQRAEHWVVVQGTAIVQVG
CCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECEEEEEEC
DEEHTTLPGQYRYIPLKEKHRLTNTGENELVLIEVQCGGYLGEDDIVRLADTYGRA
CCCCCCCCCCEEEEECHHCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]