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The map label for this gene is ybiC [H]

Identifier: 91789808

GI number: 91789808

Start: 4160994

End: 4162088

Strand: Direct

Name: ybiC [H]

Synonym: Bpro_3968

Alternate gene names: 91789808

Gene position: 4160994-4162088 (Clockwise)

Preceding gene: 91789807

Following gene: 91789809

Centisome position: 80.02

GC content: 66.12

Gene sequence:

>1095_bases
ATGGAATCCCAAAACACCTTCAATACCCTCATGAGCCACACCATCTCCGCCGCCCAGTTACGAGCCCAGGTAGCTACTGT
TTTAAAAGCCGCCGGCAGCTCCGCCGAAGAGGCCACCACCGTCGCCGCCAACCTGGTGCTGGCCAACCTGAGCGGCCACG
ACTCGCACGGCGTGGGCATGCTGCCGCGTTATGTGGATGCCGTGCTCGAAGGCGGCCTGAAACCCAACAGCAGCGTGCGG
GTAGTCCTCGACACCGGCTCGCTGCTGACACTGGACGGCCAGCGCGGCTACGGCCAGATCGTCGGCGAGCAGGCGATGGC
GCTGGGCATAGACCGCGCCAAGGCCCATGGCAGCTGCATCATGACGCTGGGCAATGCCCACCATCTGGGCCGCATCGGGC
ACTTCGCCGAAATGGCGGTGGATCAAGGCCTGGTGTCCCTGCATTTTGTCAACGTGCTGTCGCGACCGGTGGTGGCGCCG
TTTGGCGGAGGCGATGGCCGCTTTGGCACAAACCCCTGCTGCATTGGCGTGCCGCTCAAGGGCCGTGAACCCTTCGTGTT
GGACTTTGCGACCAGCCGCGTGGCGCAGGGCAAGATGCGTGTGGCCCATAACAAGGGGATTCAGGTCGAGCCCGGCACAC
TCATCGACGAACACGGACGCCCGACCACCGACCCGGGTGTGGTGGTGGTACCCCAGAGCAATGGGCTGTTTGGTGCGCTG
CTGGCTTTTGGCGAGCACAAGGGTTACGGCATGGCCGTGGCCTGCGAACTGCTGGGCGGCGCGCTGACCGGCGGCGGCAC
CTGGCACAAAGCCACCGACCCGGCCGTGCGCGCCGTCGTCAATGGCATGCTGACGATTTTGATCGACCCGGCCAAGCTGG
GCACCCAGGCCGCTTTCGAGCAGGAAGCGGTGGCCTTTGTGGACTGGCTCCAGGCCGGGCCGGTCGCACCCGGCTTTGAC
GCCGTGCAGATTGCCGGCGACCCGGAGCGCGCCACCCGCGCGCAGCGCGAAGTCGAAGGCATTGCGGTGGATGACCAGAC
CTGGCAAGAGATGGTTGCCGCCGGCCGCAAGGTCGGTGCGACCCTGCAGGACTGA

Upstream 100 bases:

>100_bases
GTCCTTTTCTTCACTCCCTCTCCCCCTGGGAGAGGGCGGGGGTGAGGGCTCTGCGCGCCGAGAGGCCCTCACCCTGACCC
TCTCCCAGGGGGGAGAGGGA

Downstream 100 bases:

>100_bases
TTTCCACAGCCCCACCATTCAGCCGAAAACACTTTTTCATCAAATACTTTTCAAATGTCTTTCAACATCATGACTCCCCC
CATTCAGGACCAGGTCGCCC

Product: hypothetical protein

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MESQNTFNTLMSHTISAAQLRAQVATVLKAAGSSAEEATTVAANLVLANLSGHDSHGVGMLPRYVDAVLEGGLKPNSSVR
VVLDTGSLLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCIMTLGNAHHLGRIGHFAEMAVDQGLVSLHFVNVLSRPVVAP
FGGGDGRFGTNPCCIGVPLKGREPFVLDFATSRVAQGKMRVAHNKGIQVEPGTLIDEHGRPTTDPGVVVVPQSNGLFGAL
LAFGEHKGYGMAVACELLGGALTGGGTWHKATDPAVRAVVNGMLTILIDPAKLGTQAAFEQEAVAFVDWLQAGPVAPGFD
AVQIAGDPERATRAQREVEGIAVDDQTWQEMVAAGRKVGATLQD

Sequences:

>Translated_364_residues
MESQNTFNTLMSHTISAAQLRAQVATVLKAAGSSAEEATTVAANLVLANLSGHDSHGVGMLPRYVDAVLEGGLKPNSSVR
VVLDTGSLLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCIMTLGNAHHLGRIGHFAEMAVDQGLVSLHFVNVLSRPVVAP
FGGGDGRFGTNPCCIGVPLKGREPFVLDFATSRVAQGKMRVAHNKGIQVEPGTLIDEHGRPTTDPGVVVVPQSNGLFGAL
LAFGEHKGYGMAVACELLGGALTGGGTWHKATDPAVRAVVNGMLTILIDPAKLGTQAAFEQEAVAFVDWLQAGPVAPGFD
AVQIAGDPERATRAQREVEGIAVDDQTWQEMVAAGRKVGATLQD
>Mature_364_residues
MESQNTFNTLMSHTISAAQLRAQVATVLKAAGSSAEEATTVAANLVLANLSGHDSHGVGMLPRYVDAVLEGGLKPNSSVR
VVLDTGSLLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCIMTLGNAHHLGRIGHFAEMAVDQGLVSLHFVNVLSRPVVAP
FGGGDGRFGTNPCCIGVPLKGREPFVLDFATSRVAQGKMRVAHNKGIQVEPGTLIDEHGRPTTDPGVVVVPQSNGLFGAL
LAFGEHKGYGMAVACELLGGALTGGGTWHKATDPAVRAVVNGMLTILIDPAKLGTQAAFEQEAVAFVDWLQAGPVAPGFD
AVQIAGDPERATRAQREVEGIAVDDQTWQEMVAAGRKVGATLQD

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=348, Percent_Identity=44.2528735632184, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1786727, Length=342, Percent_Identity=28.6549707602339, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790000, Length=340, Percent_Identity=25, Blast_Score=117, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17507179, Length=335, Percent_Identity=28.955223880597, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17536633, Length=330, Percent_Identity=26.969696969697, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24667908, Length=339, Percent_Identity=28.9085545722714, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45553211, Length=339, Percent_Identity=28.9085545722714, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667912, Length=339, Percent_Identity=28.9085545722714, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667904, Length=339, Percent_Identity=28.9085545722714, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24648360, Length=322, Percent_Identity=24.5341614906832, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24658010, Length=311, Percent_Identity=24.4372990353698, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 37863; Mature: 37863

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQNTFNTLMSHTISAAQLRAQVATVLKAAGSSAEEATTVAANLVLANLSGHDSHGVGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEEEECCCCCCCCCCH
LPRYVDAVLEGGLKPNSSVRVVLDTGSLLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCI
HHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCHHHCCCCCEE
MTLGNAHHLGRIGHFAEMAVDQGLVSLHFVNVLSRPVVAPFGGGDGRFGTNPCCIGVPLK
EEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECC
GREPFVLDFATSRVAQGKMRVAHNKGIQVEPGTLIDEHGRPTTDPGVVVVPQSNGLFGAL
CCCCEEEEHHHHHHHHCCEEEECCCCCEECCCCEECCCCCCCCCCCEEEEECCCCCHHHH
LAFGEHKGYGMAVACELLGGALTGGGTWHKATDPAVRAVVNGMLTILIDPAKLGTQAAFE
HHHCCCCCCCCEEEHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCHHHCCHHHHH
QEAVAFVDWLQAGPVAPGFDAVQIAGDPERATRAQREVEGIAVDDQTWQEMVAAGRKVGA
HHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCEEECHHHHHHHHHCCHHCCC
TLQD
CCCC
>Mature Secondary Structure
MESQNTFNTLMSHTISAAQLRAQVATVLKAAGSSAEEATTVAANLVLANLSGHDSHGVGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEEEECCCCCCCCCCH
LPRYVDAVLEGGLKPNSSVRVVLDTGSLLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCI
HHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCHHHCCCCCEE
MTLGNAHHLGRIGHFAEMAVDQGLVSLHFVNVLSRPVVAPFGGGDGRFGTNPCCIGVPLK
EEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECC
GREPFVLDFATSRVAQGKMRVAHNKGIQVEPGTLIDEHGRPTTDPGVVVVPQSNGLFGAL
CCCCEEEEHHHHHHHHCCEEEECCCCCEECCCCEECCCCCCCCCCCEEEEECCCCCHHHH
LAFGEHKGYGMAVACELLGGALTGGGTWHKATDPAVRAVVNGMLTILIDPAKLGTQAAFE
HHHCCCCCCCCEEEHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCHHHCCHHHHH
QEAVAFVDWLQAGPVAPGFDAVQIAGDPERATRAQREVEGIAVDDQTWQEMVAAGRKVGA
HHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCEEECHHHHHHHHHCCHHCCC
TLQD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]