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The map label for this gene is siaP [H]

Identifier: 91789804

GI number: 91789804

Start: 4156262

End: 4157248

Strand: Direct

Name: siaP [H]

Synonym: Bpro_3964

Alternate gene names: 91789804

Gene position: 4156262-4157248 (Clockwise)

Preceding gene: 91789803

Following gene: 91789805

Centisome position: 79.92

GC content: 58.87

Gene sequence:

>987_bases
ATGACAAAACGACTGACGATAAAAACCATGGCCCTATGCGCAATATTGGCGGGAACCATGGGGTCATTTGGCATCGCCCA
TGCGCAAACCAAGCTGAAGTGGGCCCACGTGTATGAAACGTCGGAGCCCTATCACAAGTGGTCGGTCTGGGCGGCAGACG
AGATCAAGAAGCGCACCAACGGCCGCTATGAGATCCAGGTGTTCCCGGCTTCCACGCTGGGCAAGGAAAGCGACATCAAC
CAGGGCCTGCAGCTGGGCACCGTCGACATCATCATCTCGGGCGCCTCCTTCGCTGCCCGCAGCTTTCCGCGCATCGGTGT
GGGCTACTACCCCTACACCTTCCGGGATCCAGAGCACCTGCTCAAGTATTCGAAGAGCGATGTCTTCAAGGAACTGGCCG
ACGGCTACAAGCAGAAAACCGGCGTGCAGACCGTCGCCGTCACCTACTACGGCGCACGCCACTCCACCAGCAACAAGCTC
TTCAAGAACTGCGATGAAATGAAGGGCCTGAAGATGCGGGTGCCCGACGTGCCCGCCTACATGGCCTTGCCGCGCGCCTG
CGGCGCCAACCCGACGCCGATCGCTTTTGCCGAGGTCTACCTGGCCCTGCAAAACGGCACGGTCGATGCGCAGGAAAATC
CGCTGCCCACCATCGAAGCCAAGAAGTTCTACGAGGTCCAGAAGAACATCATCCTGACCGGCCACATCCTCGATTCGCTG
GTGACGCAAGTCGGCCCCCACGTCTGGACCAAGCTCAGCGATGCGGACAAGAAAATCTTCACCGACGTGATGCAGGAAGC
AGCGGCCAGCGCCACGGCCGACATCAAGAAGCGTGAAGGCGAGCTGGTTGACGAATTCAAGAAAAAGGGCCTGAACGTCG
TCACGGTCAACAAGGACGAGTTCCGCGACCGCATCGTGAAAGCCGTGGACATGACGTCGATGGGCTACGACAAAAAGGAT
TGGAACCGCATCCAGGCCCTCAAATAA

Upstream 100 bases:

>100_bases
GAGCTGGCGCCGCGCGAAGACGAGCTGATTCCAGCGTCCAGCACTCCCCTGCTTTTACTTTCAACTTTTCACGTTCACTT
TTTTCAACCGAGGAGACAAC

Downstream 100 bases:

>100_bases
GCATCGGGTGTGCCCCGCTCAGCCCCGCTCCATATCAGCGAGGCTGAGCACTTCCGAATGCCCTCCCTTTCCCCTGGCGG
GAAGGGGCCTCTCCACCAAC

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTKRLTIKTMALCAILAGTMGSFGIAHAQTKLKWAHVYETSEPYHKWSVWAADEIKKRTNGRYEIQVFPASTLGKESDIN
QGLQLGTVDIIISGASFAARSFPRIGVGYYPYTFRDPEHLLKYSKSDVFKELADGYKQKTGVQTVAVTYYGARHSTSNKL
FKNCDEMKGLKMRVPDVPAYMALPRACGANPTPIAFAEVYLALQNGTVDAQENPLPTIEAKKFYEVQKNIILTGHILDSL
VTQVGPHVWTKLSDADKKIFTDVMQEAAASATADIKKREGELVDEFKKKGLNVVTVNKDEFRDRIVKAVDMTSMGYDKKD
WNRIQALK

Sequences:

>Translated_328_residues
MTKRLTIKTMALCAILAGTMGSFGIAHAQTKLKWAHVYETSEPYHKWSVWAADEIKKRTNGRYEIQVFPASTLGKESDIN
QGLQLGTVDIIISGASFAARSFPRIGVGYYPYTFRDPEHLLKYSKSDVFKELADGYKQKTGVQTVAVTYYGARHSTSNKL
FKNCDEMKGLKMRVPDVPAYMALPRACGANPTPIAFAEVYLALQNGTVDAQENPLPTIEAKKFYEVQKNIILTGHILDSL
VTQVGPHVWTKLSDADKKIFTDVMQEAAASATADIKKREGELVDEFKKKGLNVVTVNKDEFRDRIVKAVDMTSMGYDKKD
WNRIQALK
>Mature_327_residues
TKRLTIKTMALCAILAGTMGSFGIAHAQTKLKWAHVYETSEPYHKWSVWAADEIKKRTNGRYEIQVFPASTLGKESDINQ
GLQLGTVDIIISGASFAARSFPRIGVGYYPYTFRDPEHLLKYSKSDVFKELADGYKQKTGVQTVAVTYYGARHSTSNKLF
KNCDEMKGLKMRVPDVPAYMALPRACGANPTPIAFAEVYLALQNGTVDAQENPLPTIEAKKFYEVQKNIILTGHILDSLV
TQVGPHVWTKLSDADKKIFTDVMQEAAASATADIKKREGELVDEFKKKGLNVVTVNKDEFRDRIVKAVDMTSMGYDKKDW
NRIQALK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=303, Percent_Identity=27.7227722772277, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36687; Mature: 36555

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRLTIKTMALCAILAGTMGSFGIAHAQTKLKWAHVYETSEPYHKWSVWAADEIKKRTN
CCCEEHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCCEEEEEEHHHHHHHCC
GRYEIQVFPASTLGKESDINQGLQLGTVDIIISGASFAARSFPRIGVGYYPYTFRDPEHL
CEEEEEEECCHHCCCCCHHHCCCEECEEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHH
LKYSKSDVFKELADGYKQKTGVQTVAVTYYGARHSTSNKLFKNCDEMKGLKMRVPDVPAY
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCHH
MALPRACGANPTPIAFAEVYLALQNGTVDAQENPLPTIEAKKFYEVQKNIILTGHILDSL
HHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHCEEEEHHHHHHH
VTQVGPHVWTKLSDADKKIFTDVMQEAAASATADIKKREGELVDEFKKKGLNVVTVNKDE
HHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECHHH
FRDRIVKAVDMTSMGYDKKDWNRIQALK
HHHHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TKRLTIKTMALCAILAGTMGSFGIAHAQTKLKWAHVYETSEPYHKWSVWAADEIKKRTN
CCEEHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCCEEEEEEHHHHHHHCC
GRYEIQVFPASTLGKESDINQGLQLGTVDIIISGASFAARSFPRIGVGYYPYTFRDPEHL
CEEEEEEECCHHCCCCCHHHCCCEECEEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHH
LKYSKSDVFKELADGYKQKTGVQTVAVTYYGARHSTSNKLFKNCDEMKGLKMRVPDVPAY
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCHH
MALPRACGANPTPIAFAEVYLALQNGTVDAQENPLPTIEAKKFYEVQKNIILTGHILDSL
HHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHCEEEEHHHHHHH
VTQVGPHVWTKLSDADKKIFTDVMQEAAASATADIKKREGELVDEFKKKGLNVVTVNKDE
HHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECHHH
FRDRIVKAVDMTSMGYDKKDWNRIQALK
HHHHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA