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The map label for this gene is uxuR [H]

Identifier: 91789803

GI number: 91789803

Start: 4155380

End: 4156189

Strand: Direct

Name: uxuR [H]

Synonym: Bpro_3963

Alternate gene names: 91789803

Gene position: 4155380-4156189 (Clockwise)

Preceding gene: 91789792

Following gene: 91789804

Centisome position: 79.91

GC content: 62.72

Gene sequence:

>810_bases
ATGCCACCGCCGGTGGATTCATGGGATTATCAATTGGCCTTACCACTTGTCCAATTCTGGCTAACCCTTAATTTCGCCGC
CAAAGCCCGCATGCCCATACAAACCGTCGAACCGCAACGCCTGTACCGCCAGATTGCCGAGCAATTGCGCTCGCTGATCA
GCAAGGGCGAGTTTGCGGCTGGCAAACGCCTGCCGGCTGAGCGCGACCTGGCCAAGCAACTGGGCGTGAGCCGCCCTTCC
GTGCGTGAAGCACTGATCGCACTGGAGGTGGAAGGCTGGGTCGAAGTGCGCACCGGCTCCGGCGTTTACGTGCTGGACCG
GTCGAACCAGGTTCAGCGGAAAAACGGGCCGCAGATTGCGTCGACCGAATGGGGACCGCTGGAACTCATCCGGGCGCGCC
GCGTGGTGGAAGGCGAAATTGCCTCCATGGCCGCCGTCCAGGCCAAACGCAAAGACATTGACGCGATGCGCAAAGCCATA
GACGCCATGAAAAGCGATGCCGGGCGCGGCGTGCTGCCGCTCGAAGGCGACCGGGCATTTCATACCGCGATCGTCGAGGC
CTGCGGCAACGTGGTGCTGATCGAAACCGTCCAGAGTTTCTGGGATTCGCGCCGCGGCCCGCTGTTCACGCGCCTGGGTG
GCTATTTCGAGACCATGAAGTCATGGCAATCCGCCATCGACGAGCACGAAGCGATTTACGCCGCCATCTGCGCGCATGAC
GGCGCCGCTGCCCGCGCTGCGATGCATGCCCACATGGACAAATCCCACACCCGATTCAGCGCGAGCTGGCGCCGCGCGAA
GACGAGCTGA

Upstream 100 bases:

>100_bases
CGTTACTTCCGGTTTCATGGTGCAGAAGGGTATCCAGGGTTATTCGCGGTTATTCAGGTCGGTTATTCAGGTCATGAACG
GTATTACAGGGTTTAGCCGG

Downstream 100 bases:

>100_bases
TTCCAGCGTCCAGCACTCCCCTGCTTTTACTTTCAACTTTTCACGTTCACTTTTTTCAACCGAGGAGACAACATGACAAA
ACGACTGACGATAAAAACCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPPPVDSWDYQLALPLVQFWLTLNFAAKARMPIQTVEPQRLYRQIAEQLRSLISKGEFAAGKRLPAERDLAKQLGVSRPS
VREALIALEVEGWVEVRTGSGVYVLDRSNQVQRKNGPQIASTEWGPLELIRARRVVEGEIASMAAVQAKRKDIDAMRKAI
DAMKSDAGRGVLPLEGDRAFHTAIVEACGNVVLIETVQSFWDSRRGPLFTRLGGYFETMKSWQSAIDEHEAIYAAICAHD
GAAARAAMHAHMDKSHTRFSASWRRAKTS

Sequences:

>Translated_269_residues
MPPPVDSWDYQLALPLVQFWLTLNFAAKARMPIQTVEPQRLYRQIAEQLRSLISKGEFAAGKRLPAERDLAKQLGVSRPS
VREALIALEVEGWVEVRTGSGVYVLDRSNQVQRKNGPQIASTEWGPLELIRARRVVEGEIASMAAVQAKRKDIDAMRKAI
DAMKSDAGRGVLPLEGDRAFHTAIVEACGNVVLIETVQSFWDSRRGPLFTRLGGYFETMKSWQSAIDEHEAIYAAICAHD
GAAARAAMHAHMDKSHTRFSASWRRAKTS
>Mature_268_residues
PPPVDSWDYQLALPLVQFWLTLNFAAKARMPIQTVEPQRLYRQIAEQLRSLISKGEFAAGKRLPAERDLAKQLGVSRPSV
REALIALEVEGWVEVRTGSGVYVLDRSNQVQRKNGPQIASTEWGPLELIRARRVVEGEIASMAAVQAKRKDIDAMRKAID
AMKSDAGRGVLPLEGDRAFHTAIVEACGNVVLIETVQSFWDSRRGPLFTRLGGYFETMKSWQSAIDEHEAIYAAICAHDG
AAARAAMHAHMDKSHTRFSASWRRAKTS

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=224, Percent_Identity=36.6071428571429, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082208, Length=226, Percent_Identity=34.5132743362832, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790032, Length=227, Percent_Identity=33.0396475770925, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789353, Length=200, Percent_Identity=30.5, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786303, Length=218, Percent_Identity=31.1926605504587, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789621, Length=231, Percent_Identity=28.1385281385281, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29967; Mature: 29835

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPPVDSWDYQLALPLVQFWLTLNFAAKARMPIQTVEPQRLYRQIAEQLRSLISKGEFAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GKRLPAERDLAKQLGVSRPSVREALIALEVEGWVEVRTGSGVYVLDRSNQVQRKNGPQIA
CCCCCCHHHHHHHHCCCCCHHHHHHHHEEECCEEEEECCCCEEEEECCCCHHHCCCCCCC
STEWGPLELIRARRVVEGEIASMAAVQAKRKDIDAMRKAIDAMKSDAGRGVLPLEGDRAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
HTAIVEACGNVVLIETVQSFWDSRRGPLFTRLGGYFETMKSWQSAIDEHEAIYAAICAHD
HHHHHHHHCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAAARAAMHAHMDKSHTRFSASWRRAKTS
CHHHHHHHHHHHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPPVDSWDYQLALPLVQFWLTLNFAAKARMPIQTVEPQRLYRQIAEQLRSLISKGEFAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GKRLPAERDLAKQLGVSRPSVREALIALEVEGWVEVRTGSGVYVLDRSNQVQRKNGPQIA
CCCCCCHHHHHHHHCCCCCHHHHHHHHEEECCEEEEECCCCEEEEECCCCHHHCCCCCCC
STEWGPLELIRARRVVEGEIASMAAVQAKRKDIDAMRKAIDAMKSDAGRGVLPLEGDRAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
HTAIVEACGNVVLIETVQSFWDSRRGPLFTRLGGYFETMKSWQSAIDEHEAIYAAICAHD
HHHHHHHHCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAAARAAMHAHMDKSHTRFSASWRRAKTS
CHHHHHHHHHHHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]