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The map label for this gene is cysM [H]

Identifier: 91789572

GI number: 91789572

Start: 3933321

End: 3934223

Strand: Reverse

Name: cysM [H]

Synonym: Bpro_3726

Alternate gene names: 91789572

Gene position: 3934223-3933321 (Counterclockwise)

Preceding gene: 91789573

Following gene: 91789571

Centisome position: 75.65

GC content: 61.13

Gene sequence:

>903_bases
ATGAACTATCCAACCATTGAAGACGCGATCGGCAAAACGCCGCTGGTCGCGTTGCAGCGCATCGCAGCCGCTGAAAACAC
CGAACGCAACAACGTCATCCTCGGCAAACTCGAAGGCAACAATCCGGCCGGCTCCGTCAAGGACAGGCCAGCGCTGTCGA
TGATCAAGCGCGCCGAGGAGCGCGGCGACATCAAGCCCGGCGACATCCTCATCGAGGCCACCTCGGGCAACACCGGCATC
GCGCTGGCCATGGCGGCGGCCATCAAGGGCTATCGGATGGTGCTGATCATGCCGGAGGACCTGAGCATTGAGCGCGCCCA
GACGATGAAGGCCTTTGGCGCCGAGCTGGTGCTCACGCCCAAAAGCGGCGGTATGGAACACGCCCGGGACCTGGCCGAGC
AGATGCAAAACGAGGGCAAAGGCCGGGTGCTGGACCAGTTTGCCAACCAGGACAATCCGCGCATCCATTACGAGACCACC
GGCCCCGAAATATGGACAGATACGTCAGGCAAGGTGACACATTTTGTCAGTGCGATGGGTACAACCGGCACGATTACCGG
GGTTTCGCGCTACCTGAAAGAGAAAAATCCGGCCATACGCGTCATCGGTGCGCAACCCAGCGAAGGTTCGCGGATTCCCG
GCATCCGCAAATGGCAGCAAGAATACCTGCCCAAAATTTATGACCCCAGCCATGTGGACGAGCTGGTGCTGGTCAGCCAG
AGCGATGCGGAAGACATGTGCCGCCGGCTGGCGCGCGAAGAGGGTATTTTTGCCGGCATCTCGTCGGCTGGCGCCTGCTG
GGTGGCGCAGGAAATCGCTAAAACCGTCAAGGATGCGGTGATCGTGTTCGTCGTGTGCGACCGCGGCGACCGCTACCTGT
CTACCGGCGTCTTTCCCGCCTGA

Upstream 100 bases:

>100_bases
GGCACGCCTTTCGGCGGGGGATTTTGAGTCCCCTGCGTCTACCAATTTCACCACCCGGGCGGAAAGAAGCGAAGACCGAA
ATTATGGCACAGTGTGGCGT

Downstream 100 bases:

>100_bases
TTCACCGTGAATACTGTTTCAGGCCCATATTTTGTTGGGATAGTTTGCTATGAAAAATATAGCAAATTGTTGCGCGTGGG
GCATCAGCCATGACACACGA

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNYPTIEDAIGKTPLVALQRIAAAENTERNNVILGKLEGNNPAGSVKDRPALSMIKRAEERGDIKPGDILIEATSGNTGI
ALAMAAAIKGYRMVLIMPEDLSIERAQTMKAFGAELVLTPKSGGMEHARDLAEQMQNEGKGRVLDQFANQDNPRIHYETT
GPEIWTDTSGKVTHFVSAMGTTGTITGVSRYLKEKNPAIRVIGAQPSEGSRIPGIRKWQQEYLPKIYDPSHVDELVLVSQ
SDAEDMCRRLAREEGIFAGISSAGACWVAQEIAKTVKDAVIVFVVCDRGDRYLSTGVFPA

Sequences:

>Translated_300_residues
MNYPTIEDAIGKTPLVALQRIAAAENTERNNVILGKLEGNNPAGSVKDRPALSMIKRAEERGDIKPGDILIEATSGNTGI
ALAMAAAIKGYRMVLIMPEDLSIERAQTMKAFGAELVLTPKSGGMEHARDLAEQMQNEGKGRVLDQFANQDNPRIHYETT
GPEIWTDTSGKVTHFVSAMGTTGTITGVSRYLKEKNPAIRVIGAQPSEGSRIPGIRKWQQEYLPKIYDPSHVDELVLVSQ
SDAEDMCRRLAREEGIFAGISSAGACWVAQEIAKTVKDAVIVFVVCDRGDRYLSTGVFPA
>Mature_300_residues
MNYPTIEDAIGKTPLVALQRIAAAENTERNNVILGKLEGNNPAGSVKDRPALSMIKRAEERGDIKPGDILIEATSGNTGI
ALAMAAAIKGYRMVLIMPEDLSIERAQTMKAFGAELVLTPKSGGMEHARDLAEQMQNEGKGRVLDQFANQDNPRIHYETT
GPEIWTDTSGKVTHFVSAMGTTGTITGVSRYLKEKNPAIRVIGAQPSEGSRIPGIRKWQQEYLPKIYDPSHVDELVLVSQ
SDAEDMCRRLAREEGIFAGISSAGACWVAQEIAKTVKDAVIVFVVCDRGDRYLSTGVFPA

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=299, Percent_Identity=37.123745819398, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI295821200, Length=299, Percent_Identity=37.123745819398, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI4557415, Length=299, Percent_Identity=37.123745819398, Blast_Score=185, Evalue=5e-47,
Organism=Escherichia coli, GI2367138, Length=294, Percent_Identity=61.9047619047619, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1788754, Length=308, Percent_Identity=44.1558441558442, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17535051, Length=302, Percent_Identity=42.0529801324503, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17562970, Length=305, Percent_Identity=39.672131147541, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32566674, Length=300, Percent_Identity=40.3333333333333, Blast_Score=200, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=40, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17561720, Length=302, Percent_Identity=38.7417218543046, Blast_Score=170, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI25147552, Length=311, Percent_Identity=36.3344051446945, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17534315, Length=315, Percent_Identity=36.1904761904762, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32566672, Length=215, Percent_Identity=36.2790697674419, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321594, Length=317, Percent_Identity=35.0157728706625, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321449, Length=333, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24643623, Length=309, Percent_Identity=37.8640776699029, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20129101, Length=309, Percent_Identity=37.8640776699029, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 32600; Mature: 32600

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPTIEDAIGKTPLVALQRIAAAENTERNNVILGKLEGNNPAGSVKDRPALSMIKRAEE
CCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
RGDIKPGDILIEATSGNTGIALAMAAAIKGYRMVLIMPEDLSIERAQTMKAFGAELVLTP
HCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEC
KSGGMEHARDLAEQMQNEGKGRVLDQFANQDNPRIHYETTGPEIWTDTSGKVTHFVSAMG
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHC
TTGTITGVSRYLKEKNPAIRVIGAQPSEGSRIPGIRKWQQEYLPKIYDPSHVDELVLVSQ
CCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEC
SDAEDMCRRLAREEGIFAGISSAGACWVAQEIAKTVKDAVIVFVVCDRGDRYLSTGVFPA
CCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MNYPTIEDAIGKTPLVALQRIAAAENTERNNVILGKLEGNNPAGSVKDRPALSMIKRAEE
CCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
RGDIKPGDILIEATSGNTGIALAMAAAIKGYRMVLIMPEDLSIERAQTMKAFGAELVLTP
HCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEC
KSGGMEHARDLAEQMQNEGKGRVLDQFANQDNPRIHYETTGPEIWTDTSGKVTHFVSAMG
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHC
TTGTITGVSRYLKEKNPAIRVIGAQPSEGSRIPGIRKWQQEYLPKIYDPSHVDELVLVSQ
CCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEC
SDAEDMCRRLAREEGIFAGISSAGACWVAQEIAKTVKDAVIVFVVCDRGDRYLSTGVFPA
CCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]