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The map label for this gene is lldD [H]

Identifier: 91789525

GI number: 91789525

Start: 3889953

End: 3891104

Strand: Direct

Name: lldD [H]

Synonym: Bpro_3678

Alternate gene names: 91789525

Gene position: 3889953-3891104 (Clockwise)

Preceding gene: 91789524

Following gene: 91789540

Centisome position: 74.8

GC content: 62.67

Gene sequence:

>1152_bases
ATGCCCGTCATCACCAATATCGAAGACCTGCGCGTTCTGGCGCAAAAACGTGTTCCCCGCATGTTCTACGACTATGCCGA
CTCCGGCTCGTGGACGGAGAGCACCTACCGCGCCAACGAGAGCGACTTCCAGAAGATCAAGCTGCGCCAGCGCGTGGCCG
TCAACATGGAAAACCGCAGCACGGCGACCCGGATGGTGGGCCTGGACGTGACGATGCCAGTGGCCATTGCGCCGGTCGGG
CTGACCGGCATGCAGCATGCGGATGGCGAGATTCTGGCGGCGAAGGCGGCTGAAAAATTTGGCATTCCGTTCATTCTGTC
CACCATGAGCATCTGCTCGATTGAGGACATTGCGGCCCACACCCAATCACCATTCTGGTTTCAGCTCTACATGATGCGTG
ACCGGGACGCCATGGCGGCGATGATTGAACGTGCCCGCAAGGCCCGCTGCACCGCGCTGGTACTGACGCTGGACTTGCAG
GTGATCGGGCAGCGTCACAAGGACCTCAAGAACGGCCTGACCGCGCCCCCCAAGCCGACCCTGGCGAACATCATCAACCT
GATGACCAAGCCGCGCTGGTGCCTGGGCATGGCGGGCACCAAGCGGCACACCTTTGGCAATCTGGTGGGCCACGTCAAAG
GCGTGAGCGATATGCGCTCGCTGTCGGCCTGGACCAACGAGCAATTTGATCCGCGTCTGTCGTGGGCCGATGTGGCCTGG
GTCAAAGAGCGCTGGGGCGGCAAACTGATCCTCAAGGGGATCCAGGATGTGGAAGACGCAAAGCTGGCCGTGCAAAGCGG
CGCTGACGCCATCGTCGTCAGCAACCATGGTGGACGCCAGCTTGACGGCGCGCAGTCCAGCATCGAGGCGCTGCCTGCCA
TCGTCGATGCCGTTGGCGCCAACATTGAGGTCTGGATGGACGGCGGTATCCGCTCCGGTCAGGATGTTCTCAAAGCGTGG
GCGCTGGGCGCGCGGGGCACGCTGATCGGCCGCGCCATGGTCTATGGCCTGGGCGCCATGGGCGAAGCAGGCGTCACCAA
GGCGCTGCAGATCATCCACAAGGAGCTGGACATCACGATGGCCTTTTGCGGCAGGACTGACATCAACACCGTGGACAAGG
GCATCCTGCTGCCCGGCACTTACCCCGCCTGA

Upstream 100 bases:

>100_bases
GAAAAATTACACCGGTGCGCCTGATTCCAAAAAACTTTCAAACCGCCGGGCTGGCAAACTGGCTACGATGCGGGTCGAGA
ACCCAGGAGTTACCCCACCC

Downstream 100 bases:

>100_bases
CGGGCGAGGCCGGTGCGCAAGGGCGGGGGGGGCGGTCCAGGCCGCCCCTCACGTCGCCCCGCCTGTGCGTCAGCGCCTGG
AGCCCAAGGCTTAGAAGCTG

Product: L-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPVITNIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRSTATRMVGLDVTMPVAIAPVG
LTGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAHTQSPFWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQ
VIGQRHKDLKNGLTAPPKPTLANIINLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAW
VKERWGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGANIEVWMDGGIRSGQDVLKAW
ALGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITMAFCGRTDINTVDKGILLPGTYPA

Sequences:

>Translated_383_residues
MPVITNIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRSTATRMVGLDVTMPVAIAPVG
LTGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAHTQSPFWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQ
VIGQRHKDLKNGLTAPPKPTLANIINLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAW
VKERWGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGANIEVWMDGGIRSGQDVLKAW
ALGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITMAFCGRTDINTVDKGILLPGTYPA
>Mature_382_residues
PVITNIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRSTATRMVGLDVTMPVAIAPVGL
TGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAHTQSPFWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQV
IGQRHKDLKNGLTAPPKPTLANIINLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAWV
KERWGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGANIEVWMDGGIRSGQDVLKAWA
LGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITMAFCGRTDINTVDKGILLPGTYPA

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=377, Percent_Identity=33.1564986737401, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI54234014, Length=371, Percent_Identity=33.9622641509434, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI7705393, Length=371, Percent_Identity=33.9622641509434, Blast_Score=206, Evalue=3e-53,
Organism=Escherichia coli, GI1790033, Length=379, Percent_Identity=42.2163588390501, Blast_Score=323, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI193208036, Length=372, Percent_Identity=34.9462365591398, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI32566217, Length=292, Percent_Identity=31.8493150684932, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323587, Length=384, Percent_Identity=29.9479166666667, Blast_Score=175, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363140, Length=372, Percent_Identity=36.0215053763441, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI78707190, Length=372, Percent_Identity=36.0215053763441, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI78707188, Length=372, Percent_Identity=36.0215053763441, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 41820; Mature: 41689

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVITNIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRS
CCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHEECCCCCC
TATRMVGLDVTMPVAIAPVGLTGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAH
CCCEEEECCEECCCEEECCCCCCCCCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHH
TQSPFWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQVIGQRHKDLKNGLTAPPKPT
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCCCCCCCCH
LANIINLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAW
HHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHH
VKERWGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGA
HHHHCCCEEEEHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
NIEVWMDGGIRSGQDVLKAWALGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITM
CEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEE
AFCGRTDINTVDKGILLPGTYPA
EECCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
PVITNIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRS
CCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHEECCCCCC
TATRMVGLDVTMPVAIAPVGLTGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAH
CCCEEEECCEECCCEEECCCCCCCCCCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHH
TQSPFWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQVIGQRHKDLKNGLTAPPKPT
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCCCCCCCCH
LANIINLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAW
HHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHH
VKERWGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGA
HHHHCCCEEEEHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
NIEVWMDGGIRSGQDVLKAWALGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITM
CEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEE
AFCGRTDINTVDKGILLPGTYPA
EECCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA