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The map label for this gene is algR [H]

Identifier: 91789518

GI number: 91789518

Start: 3880473

End: 3881213

Strand: Reverse

Name: algR [H]

Synonym: Bpro_3670

Alternate gene names: 91789518

Gene position: 3881213-3880473 (Counterclockwise)

Preceding gene: 91789519

Following gene: 91789517

Centisome position: 74.63

GC content: 66.53

Gene sequence:

>741_bases
ATGAAACTCAAGGTACTGCTGGTTGATGATGAAGCACTCGCCCGCTCGCGCCTGCGCACCCTGCTGGGCGACTGCACGGC
ACCGCAGGCGGTGGTGGCTGCTGAAGCCTGCGATGCGCTGCAGGCCATGCACGCCCTGCGGCAGGACAGCTTCGATGCGG
TGTTGCTGGACATCCGCATGCCGGGCGTTGACGGCATGGCGCTGGCCCGCACCATTGCGGCCCTGCCCCGGCCGCCGGCC
GTGGTGTTTGTCACGGCGCATTCCGAGCATGCCGTGCAGGCTTTCGAGCTGGAAGCCATCGACTACCTGACCAAGCCGGT
ACGGCTGGAGCGCCTGCAGCAGGCGCTGCAGAAGGTGAGCCGGCTTGCGCAGACCGTGCTGGGGCCGCAGGCGGATGCAT
CGCGGGAGATGCTCATCATCCAGGACCGGGGGCGCACGGAGCGGGTGCCGCTGGCCGAGGTGCTCTACCTGAAGGCCGAG
CTGAAATACATCACGGTGCGCACCGCCAGCCGCAGCTACATCCTCGACGGATCACTGAGCGAGCTGGAAGAGCGTCATGC
CGCGCAGTTCATACGCATACACCGCAATGCGCTGATCGCGCGGCGCGCCGTGCGCGCGCTCGAAAAGCATTTTGATCCCG
AGGAAGGCGAAGGCTGGGCGGTGCGGCTTAACGGTATCGACGAATTGCTGGCCGTGTCGCGCCGCCAGCTCAGTGCGGTG
CGTGAGGCGATTGCGGGATGA

Upstream 100 bases:

>100_bases
CCAATGTGCGCGAGCGCCTGGTTTTGCTGCATGATGTGCAGGCACAGTTCAAGACCGTCTTCAAGGATGGCGTATTTCAG
GTCAGGCTGGAGATTCCTGC

Downstream 100 bases:

>100_bases
CGGGCGGGCCGACTCGGGGCTGGCGGCACCGGGGGCGGCAGCTGATTCCTTCCGGTGCCTGCGTCCTACACCGGCAGGCG
GGTTGTTCAGGCCCAATGGA

Product: LytR/AlgR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKLKVLLVDDEALARSRLRTLLGDCTAPQAVVAAEACDALQAMHALRQDSFDAVLLDIRMPGVDGMALARTIAALPRPPA
VVFVTAHSEHAVQAFELEAIDYLTKPVRLERLQQALQKVSRLAQTVLGPQADASREMLIIQDRGRTERVPLAEVLYLKAE
LKYITVRTASRSYILDGSLSELEERHAAQFIRIHRNALIARRAVRALEKHFDPEEGEGWAVRLNGIDELLAVSRRQLSAV
REAIAG

Sequences:

>Translated_246_residues
MKLKVLLVDDEALARSRLRTLLGDCTAPQAVVAAEACDALQAMHALRQDSFDAVLLDIRMPGVDGMALARTIAALPRPPA
VVFVTAHSEHAVQAFELEAIDYLTKPVRLERLQQALQKVSRLAQTVLGPQADASREMLIIQDRGRTERVPLAEVLYLKAE
LKYITVRTASRSYILDGSLSELEERHAAQFIRIHRNALIARRAVRALEKHFDPEEGEGWAVRLNGIDELLAVSRRQLSAV
REAIAG
>Mature_246_residues
MKLKVLLVDDEALARSRLRTLLGDCTAPQAVVAAEACDALQAMHALRQDSFDAVLLDIRMPGVDGMALARTIAALPRPPA
VVFVTAHSEHAVQAFELEAIDYLTKPVRLERLQQALQKVSRLAQTVLGPQADASREMLIIQDRGRTERVPLAEVLYLKAE
LKYITVRTASRSYILDGSLSELEERHAAQFIRIHRNALIARRAVRALEKHFDPEEGEGWAVRLNGIDELLAVSRRQLSAV
REAIAG

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=247, Percent_Identity=31.9838056680162, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI87082052, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=35.2, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27268; Mature: 27268

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKVLLVDDEALARSRLRTLLGDCTAPQAVVAAEACDALQAMHALRQDSFDAVLLDIRM
CEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
PGVDGMALARTIAALPRPPAVVFVTAHSEHAVQAFELEAIDYLTKPVRLERLQQALQKVS
CCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RLAQTVLGPQADASREMLIIQDRGRTERVPLAEVLYLKAELKYITVRTASRSYILDGSLS
HHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEEEEEEEECCCCEEECCCHH
ELEERHAAQFIRIHRNALIARRAVRALEKHFDPEEGEGWAVRLNGIDELLAVSRRQLSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHH
REAIAG
HHHHCC
>Mature Secondary Structure
MKLKVLLVDDEALARSRLRTLLGDCTAPQAVVAAEACDALQAMHALRQDSFDAVLLDIRM
CEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
PGVDGMALARTIAALPRPPAVVFVTAHSEHAVQAFELEAIDYLTKPVRLERLQQALQKVS
CCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RLAQTVLGPQADASREMLIIQDRGRTERVPLAEVLYLKAELKYITVRTASRSYILDGSLS
HHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEEEEEEEECCCCEEECCCHH
ELEERHAAQFIRIHRNALIARRAVRALEKHFDPEEGEGWAVRLNGIDELLAVSRRQLSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHH
REAIAG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]