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The map label for this gene is gph [C]

Identifier: 91789508

GI number: 91789508

Start: 3855814

End: 3856473

Strand: Reverse

Name: gph [C]

Synonym: Bpro_3658

Alternate gene names: 91789508

Gene position: 3856473-3855814 (Counterclockwise)

Preceding gene: 91789509

Following gene: 91789507

Centisome position: 74.16

GC content: 66.06

Gene sequence:

>660_bases
ATGTACACCCGAAACTTTGACCTGATCGCCTTTGACTGGGACGGCACGCTGTTCGATTCCACGAAGATCATCATGCGCTG
CATCCAGTCCGCCGTGCGGGATGTAGGCGGCACCATGCCCACCGACCAGGAGGCCGCCTATGTGATCGGCCTGGGCCTGA
TGCAGGCGCTGGCCCACGCGGCTCCCGACGTACCCGCAGAAAAATACCCCGAGTTGGGCGCGCGCTACCGCCACCATTAC
GCGGCCCACCATGACGACCTGGTCCTCTTCGATGGCGTGCTGCCGATGCTGGAGGCCCTCAAGGCGCGCGGCTTCCGGCT
GGCGGTGGCCACCGGAAAATCCCGGCGCGGGCTGGATGAGGCGCTGCGGAGCGCGGAACTCAAGGGCATGTTTCACGGCT
CGCGCACCGCTGACGAGACGGCCGGCAAGCCCGACCCGCGGATGCTGCATGAGTTAATGGAGGAATTCGGCTGCACGTCT
CAGCGGGTGTTGATGGTGGGCGACACCACGCACGACCTGCAGATGGCGTTCAATGCGGCCTGCCCCAGTGTGGGGGTGAG
CTACGGCGCGCACGAACCCGAAGCCTTCACGGCCCTGGCGCCGCGCCACGTGGCCCATTCGGTGCAGGACCTCCATGACT
GGCTGCTGGCCAATGGCTAG

Upstream 100 bases:

>100_bases
TCTGTCGGTCCGGCCCCAGGGCAGCGCAGGACCCGCCGCACAACCGTGACGCGATGGCCCTTGCCCTGCAGCGCAGGGCG
GGGCCAGCGACAATCAAGGC

Downstream 100 bases:

>100_bases
TAATGGCTAGTACTAGCGACTGAAGGGCTTCCTATGGATGAGCTGTTACCCCTGTGCAATGCCAGCGACCTGGTCGAAGG
CGGGGAGGCAGTGCCCTTCG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MYTRNFDLIAFDWDGTLFDSTKIIMRCIQSAVRDVGGTMPTDQEAAYVIGLGLMQALAHAAPDVPAEKYPELGARYRHHY
AAHHDDLVLFDGVLPMLEALKARGFRLAVATGKSRRGLDEALRSAELKGMFHGSRTADETAGKPDPRMLHELMEEFGCTS
QRVLMVGDTTHDLQMAFNAACPSVGVSYGAHEPEAFTALAPRHVAHSVQDLHDWLLANG

Sequences:

>Translated_219_residues
MYTRNFDLIAFDWDGTLFDSTKIIMRCIQSAVRDVGGTMPTDQEAAYVIGLGLMQALAHAAPDVPAEKYPELGARYRHHY
AAHHDDLVLFDGVLPMLEALKARGFRLAVATGKSRRGLDEALRSAELKGMFHGSRTADETAGKPDPRMLHELMEEFGCTS
QRVLMVGDTTHDLQMAFNAACPSVGVSYGAHEPEAFTALAPRHVAHSVQDLHDWLLANG
>Mature_219_residues
MYTRNFDLIAFDWDGTLFDSTKIIMRCIQSAVRDVGGTMPTDQEAAYVIGLGLMQALAHAAPDVPAEKYPELGARYRHHY
AAHHDDLVLFDGVLPMLEALKARGFRLAVATGKSRRGLDEALRSAELKGMFHGSRTADETAGKPDPRMLHELMEEFGCTS
QRVLMVGDTTHDLQMAFNAACPSVGVSYGAHEPEAFTALAPRHVAHSVQDLHDWLLANG

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=228, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24048; Mature: 24048

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTRNFDLIAFDWDGTLFDSTKIIMRCIQSAVRDVGGTMPTDQEAAYVIGLGLMQALAHA
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
APDVPAEKYPELGARYRHHYAAHHDDLVLFDGVLPMLEALKARGFRLAVATGKSRRGLDE
CCCCCHHHCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCHHH
ALRSAELKGMFHGSRTADETAGKPDPRMLHELMEEFGCTSQRVLMVGDTTHDLQMAFNAA
HHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHC
CPSVGVSYGAHEPEAFTALAPRHVAHSVQDLHDWLLANG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYTRNFDLIAFDWDGTLFDSTKIIMRCIQSAVRDVGGTMPTDQEAAYVIGLGLMQALAHA
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
APDVPAEKYPELGARYRHHYAAHHDDLVLFDGVLPMLEALKARGFRLAVATGKSRRGLDE
CCCCCHHHCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCHHH
ALRSAELKGMFHGSRTADETAGKPDPRMLHELMEEFGCTSQRVLMVGDTTHDLQMAFNAA
HHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHC
CPSVGVSYGAHEPEAFTALAPRHVAHSVQDLHDWLLANG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA