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The map label for this gene is fabF [H]

Identifier: 91789495

GI number: 91789495

Start: 3845822

End: 3847066

Strand: Reverse

Name: fabF [H]

Synonym: Bpro_3645

Alternate gene names: 91789495

Gene position: 3847066-3845822 (Counterclockwise)

Preceding gene: 91789496

Following gene: 91789494

Centisome position: 73.98

GC content: 59.92

Gene sequence:

>1245_bases
ATGAGCCGTCGTCGTGTCGTCGTGACAGGTTTGGGTTGCGTGAGCCCGGTAGGTACTACCGTCGCCGATTCCTGGACCAA
TTTGCTTGCCGGTACTCCCGGCATTGACCTGATCACGCAATTTGATGCAAGCAACTTTGCCTGCAAGTTTGCGGGCGAGG
TGAAGGGTTTCAAGATCGAGGATTACATCCCCGAAAAGGAGGCCCGGCACATGGACCGCTTCATTCACCTGGGCTTGGCT
GCGGCGTGCCAGGCGGTCGCTGACAGTGGCTTGCCTACGGGAGATGCGCTCGGTGAAGAACTGGCTACCCGCATCGGTTG
CAACATCGGCTCGGGCATAGGCGGTTTGCCCATGATCGAGCAGACACACGCCGAACTGGTGAATCGCGGCCCGCGCCGCA
TTTCCCCGTTTTTTGTGCCTGCGTCCATCATCAACATGATCTCCGGGCATGTTTCCATCAAGTTTGGCTTCAAGGGGCCC
AACATCGCTGTCGTGACGGCCTGCACGACTGGTCTTCATGCCATCGGACTGTCGGCGCGCATGATCGAGTACGGTGACTG
CGACGTGATGGTCGCCGGCGGTGCCGAGTCCTGCGTCTCGCCTTTGGGTGTTGGCGGCTTTGCCGCGGCCCGCGCGCTGT
CGACCCGCAATGACGACCCCAAGACCGCTTCACGTCCCTGGGACAAGGACCGCGACGGGTTTGTGTTGGGCGAGGGCGGC
GGTGTTCTGGTGCTCGAGGAGTACGAGCACGCGAAGGCGCGCGGCGCGAAGATCTATGCTGAAGTCATCGGTTTTGGCAT
GAGCGCCGACGCCTATCACATGACCTCACCCGACATCAATGGCCCCCGCCGTTCGATGGCCATGGCATTGAAAAATGCAG
GCGTCAATGCCGATCAGGTTCAGTACCTCAATGCGCACGGAACCTCCACGCCGCTGGGTGACCTGAACGAAACCAATGCC
ATCAAGGCGGCATTTGGCAGCCACGCAAAGAACATGGTGGTCAGTTCGACCAAGTCGATGACGGGCCATCTGCTGGGCGG
CGCCGGCGGCATTGAGTCGGTATTCACCGTGCTGGCGTTGCATCACCAGAAGATTCCTCCGACCATCAACATGTTCAGCC
AGGATCCCGAGTGCGACCTGGATTACTGCGCCAACGTGGCGCGCGACGCCAACATTGAGTTTGCGGTCAAAAACAATTTT
GGATTCGGCGGCACCAACGGCACGCTGGTTTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
TCAAAAGGCTTGAGGCACGAGGTTCTTGACCTTTGCCTTTGCCGTCATTCAACCTGAAAGGCCGTGCAGGGTCTTTTCGG
GTTTTTTTCAGGATTACTGA

Downstream 100 bases:

>100_bases
CGCGCCCCGGTTTCGCCTTTTCAAGCACGCGCGCCCCAGCACCGCACTGATTGTCTTGATCACGCACAACGCCCCGCCGG
TTGTCTATCCGCTGGGGCGT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSRRRVVVTGLGCVSPVGTTVADSWTNLLAGTPGIDLITQFDASNFACKFAGEVKGFKIEDYIPEKEARHMDRFIHLGLA
AACQAVADSGLPTGDALGEELATRIGCNIGSGIGGLPMIEQTHAELVNRGPRRISPFFVPASIINMISGHVSIKFGFKGP
NIAVVTACTTGLHAIGLSARMIEYGDCDVMVAGGAESCVSPLGVGGFAAARALSTRNDDPKTASRPWDKDRDGFVLGEGG
GVLVLEEYEHAKARGAKIYAEVIGFGMSADAYHMTSPDINGPRRSMAMALKNAGVNADQVQYLNAHGTSTPLGDLNETNA
IKAAFGSHAKNMVVSSTKSMTGHLLGGAGGIESVFTVLALHHQKIPPTINMFSQDPECDLDYCANVARDANIEFAVKNNF
GFGGTNGTLVFKRV

Sequences:

>Translated_414_residues
MSRRRVVVTGLGCVSPVGTTVADSWTNLLAGTPGIDLITQFDASNFACKFAGEVKGFKIEDYIPEKEARHMDRFIHLGLA
AACQAVADSGLPTGDALGEELATRIGCNIGSGIGGLPMIEQTHAELVNRGPRRISPFFVPASIINMISGHVSIKFGFKGP
NIAVVTACTTGLHAIGLSARMIEYGDCDVMVAGGAESCVSPLGVGGFAAARALSTRNDDPKTASRPWDKDRDGFVLGEGG
GVLVLEEYEHAKARGAKIYAEVIGFGMSADAYHMTSPDINGPRRSMAMALKNAGVNADQVQYLNAHGTSTPLGDLNETNA
IKAAFGSHAKNMVVSSTKSMTGHLLGGAGGIESVFTVLALHHQKIPPTINMFSQDPECDLDYCANVARDANIEFAVKNNF
GFGGTNGTLVFKRV
>Mature_413_residues
SRRRVVVTGLGCVSPVGTTVADSWTNLLAGTPGIDLITQFDASNFACKFAGEVKGFKIEDYIPEKEARHMDRFIHLGLAA
ACQAVADSGLPTGDALGEELATRIGCNIGSGIGGLPMIEQTHAELVNRGPRRISPFFVPASIINMISGHVSIKFGFKGPN
IAVVTACTTGLHAIGLSARMIEYGDCDVMVAGGAESCVSPLGVGGFAAARALSTRNDDPKTASRPWDKDRDGFVLGEGGG
VLVLEEYEHAKARGAKIYAEVIGFGMSADAYHMTSPDINGPRRSMAMALKNAGVNADQVQYLNAHGTSTPLGDLNETNAI
KAAFGSHAKNMVVSSTKSMTGHLLGGAGGIESVFTVLALHHQKIPPTINMFSQDPECDLDYCANVARDANIEFAVKNNFG
FGGTNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=418, Percent_Identity=47.6076555023923, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI223972627, Length=160, Percent_Identity=48.75, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI41872631, Length=428, Percent_Identity=24.7663551401869, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1787337, Length=417, Percent_Identity=61.1510791366906, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=37.3493975903614, Blast_Score=239, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=36.8421052631579, Blast_Score=247, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=41.1764705882353, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI212642053, Length=362, Percent_Identity=25.414364640884, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=286, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=445, Percent_Identity=39.1011235955056, Blast_Score=283, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24644341, Length=417, Percent_Identity=43.6450839328537, Blast_Score=334, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=24.0654205607477, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI221330659, Length=401, Percent_Identity=25.9351620947631, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19920632, Length=401, Percent_Identity=25.9351620947631, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43535; Mature: 43404

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGCVSPVGTTVADSWTNLLAGTPGIDLITQFDASNFACKFAGEVKGFKIE
CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCEEEC
DYIPEKEARHMDRFIHLGLAAACQAVADSGLPTGDALGEELATRIGCNIGSGIGGLPMIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
QTHAELVNRGPRRISPFFVPASIINMISGHVSIKFGFKGPNIAVVTACTTGLHAIGLSAR
HHHHHHHHCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCHHHHCCCEE
MIEYGDCDVMVAGGAESCVSPLGVGGFAAARALSTRNDDPKTASRPWDKDRDGFVLGEGG
EEEECCCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
GVLVLEEYEHAKARGAKIYAEVIGFGMSADAYHMTSPDINGPRRSMAMALKNAGVNADQV
CEEEEECCCCHHHCCCEEEEHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHE
QYLNAHGTSTPLGDLNETNAIKAAFGSHAKNMVVSSTKSMTGHLLGGAGGIESVFTVLAL
EEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHEEECCHHHCCEEECCCCCHHHHHHHHHH
HHQKIPPTINMFSQDPECDLDYCANVARDANIEFAVKNNFGFGGTNGTLVFKRV
HHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGCVSPVGTTVADSWTNLLAGTPGIDLITQFDASNFACKFAGEVKGFKIE
CCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCEEEC
DYIPEKEARHMDRFIHLGLAAACQAVADSGLPTGDALGEELATRIGCNIGSGIGGLPMIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
QTHAELVNRGPRRISPFFVPASIINMISGHVSIKFGFKGPNIAVVTACTTGLHAIGLSAR
HHHHHHHHCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCHHHHCCCEE
MIEYGDCDVMVAGGAESCVSPLGVGGFAAARALSTRNDDPKTASRPWDKDRDGFVLGEGG
EEEECCCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
GVLVLEEYEHAKARGAKIYAEVIGFGMSADAYHMTSPDINGPRRSMAMALKNAGVNADQV
CEEEEECCCCHHHCCCEEEEHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHE
QYLNAHGTSTPLGDLNETNAIKAAFGSHAKNMVVSSTKSMTGHLLGGAGGIESVFTVLAL
EEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHEEECCHHHCCEEECCCCCHHHHHHHHHH
HHQKIPPTINMFSQDPECDLDYCANVARDANIEFAVKNNFGFGGTNGTLVFKRV
HHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]