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The map label for this gene is mcl1 [H]

Identifier: 91789448

GI number: 91789448

Start: 3799029

End: 3800099

Strand: Reverse

Name: mcl1 [H]

Synonym: Bpro_3597

Alternate gene names: 91789448

Gene position: 3800099-3799029 (Counterclockwise)

Preceding gene: 91789449

Following gene: 91789447

Centisome position: 73.08

GC content: 63.59

Gene sequence:

>1071_bases
GTGCGCCGCGCCGGGCCGCCCCAAGCAAGCACAGCCCCCTCGGGGGGCAGCGAAGTACGCGAAGCGACAAGCGTGGGGGC
CAGTGTTCATCCGCGCGACGTTCTCCTCGGCGCTCAGGCCGCTACGGGTTTCTTGCCGGTCTGCGACCATTACAGTGGCG
TGGAGGCGCGGATGCGCAAAAGCCTGCAACTGCAGGCTGAAATGTGCGAGGAGTTTGGCGCCTGCGTTTTTGACGTGACG
CTGGACTGCGAAGACGGCGCACCCGTAGGCGGCGAGGCCGACCACGCGGCCATGGTGGTAGCACTGGCCACGCTTGCCAG
CGACAAAGCCCGGGTGGCCGTTCGCGTGCATGCCGTGGACCACCCCGCTTTTGAGTCCGACATGGCCACCATTGCCAGCA
AGCTGGCGCAACGGCTTTCGCACATCATGGTGCCCAAGGTCGAGTCGGTCGATGACGTGATCAGGGCAGAACAGGCGCTC
ATCGCCGCATCGGCCGACGCCCTGCCGCTGCATGTGCTGATCGAATCGCCGCTCGCAGTGCACAACGCCTTTGACATTGC
AGCCCATCCGCGGGTGCAGTCGCTCAGCTTCGGGCTGATGGATTTTGTCTCTGCCCATGGCGGTGCGATTCCAGCAGAAG
GCATGAGCAGCCAGGGCCAGTTTACCCACCCCCTCGTGGTGCGTGCCAAGCTGGAGATTGCCTCCGCCTGCCACGCCCAT
GGCAAGGTGCCCTCGCACTGTGTTGTCACGGAATTCAATGACGCAGCAGCGATGACCACCGCCGCCCGCCATGCCGCCCG
TCAGTTGGGCTACACCCGCATGTGGAGCATTCACCCCAACCAGATCCGCCCCATCCTGGAGGCCTTTGCGCCCAGCGAGG
GCGAGATTGAAGATGCTACGAAAATGATAGCTGCCGCTCAAAGGGCTGATTGGGCTCCCATCAGTTTTGAAGGTAAATTG
CACGACCGCGCGAGTTACCGTTATTACTGGCAGGTGCTGGAGCGCGCGCACCAGACGGGTCGGGCACTGCCCGCCGAAGC
CCAGACTTATTTCCAGACCGCTCATTCCTGA

Upstream 100 bases:

>100_bases
GAGATTGACGCGTTCAGCCAGGAGCGTATCAACAAGACGCTGGAAGAATTGCAAGGCGAGCAGGCCGGCGTTGCCCATTT
GCTTTAAAGCAGTGAGCATA

Downstream 100 bases:

>100_bases
GCATCCCCTCACCAAGATTGTCACCAACCGCATGAAAACCATTCACTCCACAACCCTTGCTGCCGCTGCAGCCACCATGG
TCGCTGCTGTTTTGCTGGCC

Product: HpcH/HpaI aldolase

Products: NA

Alternate protein names: (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; L-malyl-CoA/beta-methylmalyl-CoA lyase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRRAGPPQASTAPSGGSEVREATSVGASVHPRDVLLGAQAATGFLPVCDHYSGVEARMRKSLQLQAEMCEEFGACVFDVT
LDCEDGAPVGGEADHAAMVVALATLASDKARVAVRVHAVDHPAFESDMATIASKLAQRLSHIMVPKVESVDDVIRAEQAL
IAASADALPLHVLIESPLAVHNAFDIAAHPRVQSLSFGLMDFVSAHGGAIPAEGMSSQGQFTHPLVVRAKLEIASACHAH
GKVPSHCVVTEFNDAAAMTTAARHAARQLGYTRMWSIHPNQIRPILEAFAPSEGEIEDATKMIAAAQRADWAPISFEGKL
HDRASYRYYWQVLERAHQTGRALPAEAQTYFQTAHS

Sequences:

>Translated_356_residues
MRRAGPPQASTAPSGGSEVREATSVGASVHPRDVLLGAQAATGFLPVCDHYSGVEARMRKSLQLQAEMCEEFGACVFDVT
LDCEDGAPVGGEADHAAMVVALATLASDKARVAVRVHAVDHPAFESDMATIASKLAQRLSHIMVPKVESVDDVIRAEQAL
IAASADALPLHVLIESPLAVHNAFDIAAHPRVQSLSFGLMDFVSAHGGAIPAEGMSSQGQFTHPLVVRAKLEIASACHAH
GKVPSHCVVTEFNDAAAMTTAARHAARQLGYTRMWSIHPNQIRPILEAFAPSEGEIEDATKMIAAAQRADWAPISFEGKL
HDRASYRYYWQVLERAHQTGRALPAEAQTYFQTAHS
>Mature_356_residues
MRRAGPPQASTAPSGGSEVREATSVGASVHPRDVLLGAQAATGFLPVCDHYSGVEARMRKSLQLQAEMCEEFGACVFDVT
LDCEDGAPVGGEADHAAMVVALATLASDKARVAVRVHAVDHPAFESDMATIASKLAQRLSHIMVPKVESVDDVIRAEQAL
IAASADALPLHVLIESPLAVHNAFDIAAHPRVQSLSFGLMDFVSAHGGAIPAEGMSSQGQFTHPLVVRAKLEIASACHAH
GKVPSHCVVTEFNDAAAMTTAARHAARQLGYTRMWSIHPNQIRPILEAFAPSEGEIEDATKMIAAAQRADWAPISFEGKL
HDRASYRYYWQVLERAHQTGRALPAEAQTYFQTAHS

Specific function: Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to beta-methylmalyl-CoA [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.24 [H]

Molecular weight: Translated: 38076; Mature: 38076

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAGPPQASTAPSGGSEVREATSVGASVHPRDVLLGAQAATGFLPVCDHYSGVEARMRK
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHEEECHHHCCCCHHHCCCCCHHHHHHH
SLQLQAEMCEEFGACVFDVTLDCEDGAPVGGEADHAAMVVALATLASDKARVAVRVHAVD
HHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECC
HPAFESDMATIASKLAQRLSHIMVPKVESVDDVIRAEQALIAASADALPLHVLIESPLAV
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
HNAFDIAAHPRVQSLSFGLMDFVSAHGGAIPAEGMSSQGQFTHPLVVRAKLEIASACHAH
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHC
GKVPSHCVVTEFNDAAAMTTAARHAARQLGYTRMWSIHPNQIRPILEAFAPSEGEIEDAT
CCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHH
KMIAAAQRADWAPISFEGKLHDRASYRYYWQVLERAHQTGRALPAEAQTYFQTAHS
HHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRRAGPPQASTAPSGGSEVREATSVGASVHPRDVLLGAQAATGFLPVCDHYSGVEARMRK
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHEEECHHHCCCCHHHCCCCCHHHHHHH
SLQLQAEMCEEFGACVFDVTLDCEDGAPVGGEADHAAMVVALATLASDKARVAVRVHAVD
HHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECC
HPAFESDMATIASKLAQRLSHIMVPKVESVDDVIRAEQALIAASADALPLHVLIESPLAV
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
HNAFDIAAHPRVQSLSFGLMDFVSAHGGAIPAEGMSSQGQFTHPLVVRAKLEIASACHAH
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHC
GKVPSHCVVTEFNDAAAMTTAARHAARQLGYTRMWSIHPNQIRPILEAFAPSEGEIEDAT
CCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHH
KMIAAAQRADWAPISFEGKLHDRASYRYYWQVLERAHQTGRALPAEAQTYFQTAHS
HHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA