Click here to switch to the map view.

The map label for this gene is kynB

Identifier: 91789439

GI number: 91789439

Start: 3786157

End: 3786822

Strand: Direct

Name: kynB

Synonym: Bpro_3588

Alternate gene names: 91789439

Gene position: 3786157-3786822 (Clockwise)

Preceding gene: 91789434

Following gene: 91789440

Centisome position: 72.81

GC content: 67.57

Gene sequence:

>666_bases
ATGACAGCCAGAGTCCTACCATCCACCACCGCAAAGCCCTTGAGGCTTTGGGACATCTCGCCCCCCGTGGCGCCAGGCTC
GCCGGTTTTTCCGGGCGACACGCCCTACCAGCAGCAATGGGCCGCGAGCATCGCGCCGGGCTGCCCGGTGAACGTCAGCA
CCCTCACCTTGTCGCCGCACATCGGCGCACATGCCGACGCACCGTTGCACTACGACCCGCAGGGCGCCACCATCGGTGCG
GTCGATCTCACGCCCTATATCGGGCCATGCCGCGTCATTCATGCCATCGCCAAAGGGCCGCTGATCGAGTGGGAGCACCT
GGCGCATGCCGTACACGACCTGCCGCCGCGCGTGCTGGTTCGCACCTACGCGCGCATGCCAGTCGAGCGCTGGGACCCCA
CGCTCGCGGCCTACGCGCCCGAGACCGTTGAGCGCCTCGCCGCACTCGGCGTCAAGCTGATCGGCATCGACACCGCCAGC
ATCGACCCGGCCGGAAGCAAAACCCTGGACAGCCACCAGGTGATCCGCCAGCGCGGCCTGCGCGTGCTGGAAAACCTGGT
GCTCGACGAGGTGCCCGAAGGCGACTACGAACTGATTGCCCTGCCGCTCAAGCTGATGACGGCCGATGCCTCCCCCGTTC
GCGCAGTCTTGCGCGAACTCCCCTGA

Upstream 100 bases:

>100_bases
CGACTTCTTTGCCGGCAATTACTTTAGGTTTAAACTATTTTTATCACTTGTTGGAAATAACCGACACCACGGCTTTTTCG
GCGGTGCTACCTTTACACGT

Downstream 100 bases:

>100_bases
AAGATGAACCTGACATGAGCACAACTCTGCAAGATTGCCGCGCACTCGATGCGCAAGACCCACTGCGTACCCTGCGCGAC
CAGTTCACCCTGCCCGAAGG

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTARVLPSTTAKPLRLWDISPPVAPGSPVFPGDTPYQQQWAASIAPGCPVNVSTLTLSPHIGAHADAPLHYDPQGATIGA
VDLTPYIGPCRVIHAIAKGPLIEWEHLAHAVHDLPPRVLVRTYARMPVERWDPTLAAYAPETVERLAALGVKLIGIDTAS
IDPAGSKTLDSHQVIRQRGLRVLENLVLDEVPEGDYELIALPLKLMTADASPVRAVLRELP

Sequences:

>Translated_221_residues
MTARVLPSTTAKPLRLWDISPPVAPGSPVFPGDTPYQQQWAASIAPGCPVNVSTLTLSPHIGAHADAPLHYDPQGATIGA
VDLTPYIGPCRVIHAIAKGPLIEWEHLAHAVHDLPPRVLVRTYARMPVERWDPTLAAYAPETVERLAALGVKLIGIDTAS
IDPAGSKTLDSHQVIRQRGLRVLENLVLDEVPEGDYELIALPLKLMTADASPVRAVLRELP
>Mature_220_residues
TARVLPSTTAKPLRLWDISPPVAPGSPVFPGDTPYQQQWAASIAPGCPVNVSTLTLSPHIGAHADAPLHYDPQGATIGAV
DLTPYIGPCRVIHAIAKGPLIEWEHLAHAVHDLPPRVLVRTYARMPVERWDPTLAAYAPETVERLAALGVKLIGIDTASI
DPAGSKTLDSHQVIRQRGLRVLENLVLDEVPEGDYELIALPLKLMTADASPVRAVLRELP

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_POLSJ (Q126P9)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550391.1
- ProteinModelPortal:   Q126P9
- SMR:   Q126P9
- STRING:   Q126P9
- GeneID:   4013734
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3588
- NMPDR:   fig|296591.1.peg.5184
- eggNOG:   COG1878
- HOGENOM:   HBG686791
- OMA:   CPVNVGR
- ProtClustDB:   CLSK953240
- BioCyc:   PSP296591:BPRO_3588-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 23811; Mature: 23680

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARVLPSTTAKPLRLWDISPPVAPGSPVFPGDTPYQQQWAASIAPGCPVNVSTLTLSPH
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCC
IGAHADAPLHYDPQGATIGAVDLTPYIGPCRVIHAIAKGPLIEWEHLAHAVHDLPPRVLV
CCCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHH
RTYARMPVERWDPTLAAYAPETVERLAALGVKLIGIDTASIDPAGSKTLDSHQVIRQRGL
HHHHHCCHHHCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
RVLENLVLDEVPEGDYELIALPLKLMTADASPVRAVLRELP
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TARVLPSTTAKPLRLWDISPPVAPGSPVFPGDTPYQQQWAASIAPGCPVNVSTLTLSPH
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCC
IGAHADAPLHYDPQGATIGAVDLTPYIGPCRVIHAIAKGPLIEWEHLAHAVHDLPPRVLV
CCCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHH
RTYARMPVERWDPTLAAYAPETVERLAALGVKLIGIDTASIDPAGSKTLDSHQVIRQRGL
HHHHHCCHHHCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
RVLENLVLDEVPEGDYELIALPLKLMTADASPVRAVLRELP
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA