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The map label for this gene is pdxH [H]

Identifier: 91789413

GI number: 91789413

Start: 3758834

End: 3759553

Strand: Direct

Name: pdxH [H]

Synonym: Bpro_3559

Alternate gene names: 91789413

Gene position: 3758834-3759553 (Clockwise)

Preceding gene: 91789408

Following gene: 91789420

Centisome position: 72.28

GC content: 62.36

Gene sequence:

>720_bases
ATGAACAGCGCCATGCCAGCCTGGAACAACCACGCAGGGGCACCCCCTGAACCGTGCACAATCACAAGCATGAGCAACCC
CATCATTGACATTGCAGCCCTGCGCAAAAGCTACGAACGCGCCGAGCTCAATGAGGACGCGTCGCATGCCGATCCCTTGA
AGCAGTTCGACCAGTGGCTGAACGAGGCGATTGCCGCGCAGGTGCCGGAGCCCAATGCGATGACGCTGGCGACCGTGGAC
AGCAAGCTGCGACCCTCCACCCGTGTGGTGCTGGTCAAGGGTTATGACGCGCGCGGCATTGTCTGGTTTACCAATTACAA
CAGCCGCAAGGGCCTCGAGCTGGCCGGCAACCCCTATGCAGCCTTGCAGTTTCACTGGGTAGAACTGGAACGCGTGGTGC
GCATCGAAGGCGTGGTCGAAAAAGTCTCCGCGGAAGAAAGTGATGCCTACTTCAACAGCCGCCCGCTGGATTCTCGTATT
GGCGCCTGGGCCAGTCCGCAAAGCGAAGTCATTGCCAGCCGCAGTGTGCTGGTGACCAATGCGGCCAAATATGGCGCCAA
ATTCCTGCTGCAGCCGCCGCGCCCGCCGCACTGGGGTGGCTACCGCCTCCAGCCCGACAACTGGCAGTTCTGGCAGGGCC
GCAAAAGCCGGCTGCATGACCGCCTGCGTTACACGCTGCAAGCCGACTCCAGCTGGCTGCGCGAGCGCCTGGCGCCCTGA

Upstream 100 bases:

>100_bases
GCTTCGGCGATGGCACGCTGCTTTTCCTCATCTTTGGGTTTCATGTCAGGCGAAATATAACCGAATATTAATTCGCTTTC
AAGCACCCCTCAAACAGGCC

Downstream 100 bases:

>100_bases
GCTTTCTTCTCAGACCGTGAAGTCGCCCAGCCGCTCAATGGCCTGGTGCGCCACCGCCGCGAGCTGTTCGGGGCTCACCC
GCTCCGGTGCAATTTCCGCC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNSAMPAWNNHAGAPPEPCTITSMSNPIIDIAALRKSYERAELNEDASHADPLKQFDQWLNEAIAAQVPEPNAMTLATVD
SKLRPSTRVVLVKGYDARGIVWFTNYNSRKGLELAGNPYAALQFHWVELERVVRIEGVVEKVSAEESDAYFNSRPLDSRI
GAWASPQSEVIASRSVLVTNAAKYGAKFLLQPPRPPHWGGYRLQPDNWQFWQGRKSRLHDRLRYTLQADSSWLRERLAP

Sequences:

>Translated_239_residues
MNSAMPAWNNHAGAPPEPCTITSMSNPIIDIAALRKSYERAELNEDASHADPLKQFDQWLNEAIAAQVPEPNAMTLATVD
SKLRPSTRVVLVKGYDARGIVWFTNYNSRKGLELAGNPYAALQFHWVELERVVRIEGVVEKVSAEESDAYFNSRPLDSRI
GAWASPQSEVIASRSVLVTNAAKYGAKFLLQPPRPPHWGGYRLQPDNWQFWQGRKSRLHDRLRYTLQADSSWLRERLAP
>Mature_239_residues
MNSAMPAWNNHAGAPPEPCTITSMSNPIIDIAALRKSYERAELNEDASHADPLKQFDQWLNEAIAAQVPEPNAMTLATVD
SKLRPSTRVVLVKGYDARGIVWFTNYNSRKGLELAGNPYAALQFHWVELERVVRIEGVVEKVSAEESDAYFNSRPLDSRI
GAWASPQSEVIASRSVLVTNAAKYGAKFLLQPPRPPHWGGYRLQPDNWQFWQGRKSRLHDRLRYTLQADSSWLRERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=41.304347826087, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1787926, Length=218, Percent_Identity=41.743119266055, Blast_Score=172, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17553712, Length=231, Percent_Identity=40.2597402597403, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319509, Length=219, Percent_Identity=41.0958904109589, Blast_Score=146, Evalue=3e-36,
Organism=Drosophila melanogaster, GI45551845, Length=243, Percent_Identity=42.798353909465, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24644901, Length=232, Percent_Identity=43.1034482758621, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24644903, Length=215, Percent_Identity=29.3023255813954, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 26996; Mature: 26996

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSAMPAWNNHAGAPPEPCTITSMSNPIIDIAALRKSYERAELNEDASHADPLKQFDQWL
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NEAIAAQVPEPNAMTLATVDSKLRPSTRVVLVKGYDARGIVWFTNYNSRKGLELAGNPYA
HHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCEECCCCEE
ALQFHWVELERVVRIEGVVEKVSAEESDAYFNSRPLDSRIGAWASPQSEVIASRSVLVTN
EEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHCEEEEEC
AAKYGAKFLLQPPRPPHWGGYRLQPDNWQFWQGRKSRLHDRLRYTLQADSSWLRERLAP
CHHHCCEEEECCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHEEECCCHHHHHHHCCC
>Mature Secondary Structure
MNSAMPAWNNHAGAPPEPCTITSMSNPIIDIAALRKSYERAELNEDASHADPLKQFDQWL
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NEAIAAQVPEPNAMTLATVDSKLRPSTRVVLVKGYDARGIVWFTNYNSRKGLELAGNPYA
HHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCEECCCCEE
ALQFHWVELERVVRIEGVVEKVSAEESDAYFNSRPLDSRIGAWASPQSEVIASRSVLVTN
EEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHCEEEEEC
AAKYGAKFLLQPPRPPHWGGYRLQPDNWQFWQGRKSRLHDRLRYTLQADSSWLRERLAP
CHHHCCEEEECCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHEEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA