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The map label for this gene is aphA [H]

Identifier: 91789364

GI number: 91789364

Start: 3711583

End: 3713148

Strand: Direct

Name: aphA [H]

Synonym: Bpro_3510

Alternate gene names: 91789364

Gene position: 3711583-3713148 (Clockwise)

Preceding gene: 91789363

Following gene: 91789365

Centisome position: 71.37

GC content: 63.73

Gene sequence:

>1566_bases
ATGGAACAAGTGCTGAACAAAATTCGTGTCCTCGTCGTGGAGGATGAAATCGTCGTATCGGAAGACCTGCAGCAACGGCT
GTCGGGGCTCGGGTACGAAATCACCGGCGCGGCGGACACCGCGGCCGCTGCGATCCGGCTTGCCGCATCGCAGCGGCCCG
ACGTGGCTCTGATGGATATCATGTTGCACGGCCGGCCCGAGGGTATCGACGCTGCCGAACACCTGCGCGGCGAGCTGGAC
ATTCCGGTCATCTATCTCACCGCACACAGCGATACGGCCACCCTGCATAGAGCCAGGTTCACCGACCCTTCGGGCTACAT
CGTCAAACCGTTCGATGACCAGCAACTGCGCGTCGCCATCGAACTGGCGCCGTTTCGCCATGAGATGGAGCGCAAGGCTC
GCCGGGTCGCCCGCTGGATGACTGCCACGCTGACGAGCATCGGCGACGCCGTCATCGCCACCAACACCCATTCAGAAATT
CTGCTGCTCAATCCTGCCGCGGAGAAGCTGACCGGCTGGACGCAGGATGAGGCTACCGGAAAGCCATCCGGCGAAGTGGT
GCGCCTGGTGAACCAGAAAACCCGCCAGCCTCTGGAAGACCCGGCCACACGCGCCCTGCGCGATGGCCTGGTCGTTCGTT
TGGACCCGGACACCGTGCTGATCACGCGCGAGGGCGGAGAACGCTTTGTGGATGACAGCGCTTCGCCCATTACCGACGAA
ACCGGCAAGGTCCTGGGCGCTGTCGTGGTGCTGGTCGATGCCACGGGCCGGGTCGCCGCGCAGAACCGCGTGGATACCTT
GACGCGCCAGGTGAAGGGGCTGCTCGCCGAGAAGGACAACTATGAACTGAAAGGCGCTGAACTCGAAGCCTTCGCCACTG
CCGTGAGCCACGACTTGCGGGGGCCGCTGCAGGCCATTGCCGGCTTCTCCGAGCTTCTGGCCCGGTCGCAGCGCGAGCGG
CTCGACGCCTCGGGACAACTGTTCCTCGATCGGGTTCACGCAAGCGCGCTGCAAATGGGCTGCATGGTGGAGGACTATCT
GGGCTTTTTGAAATCGAATCGCGAGCAAACACTTAGCGTGACAGAGCTGGACCTGAAGCACCTCGCGCACGCAGTGTTTG
CCGAACTCGCCCTCGTGCCGGGCCAGAAGCCGGCGCAGTTCGTGTGCGAGGAATTGCCGCGGGCCTGGGGCGACGAGGCC
ATGCTCCGGCAGGTGCTCGTCAACCTGATCGGCAATGCGCTCAAGTATTCGGCGCAGCGGGAGCATCCGATGGTGGAAGT
CGGCGCGATAGCAGGTGAAGAAGCGGGCGAGGACTGCCATACCTTCTTCGTCCGTGACAACGGTGCGGGCCTGGATCTCG
CGAACGCAGCGAAACTCTTCGAGCCGTTTCAACGCTTCCACAGCACGGCCGAATTCCCCGGCACCGGGGTGGGCTTGGCC
ATCGTCAAACGCATCGTCGAACGCCACGGTGGCCGGATGTTGGCCGAGAGCCAGCCTGATGCCGGCGCCACGTTTTTCTT
CACCTTGCCGTCGAAGGCTCCCGGCATGACGGCGGCCCTGCAATGA

Upstream 100 bases:

>100_bases
CAAACAATTACGCGCCAACGTGACACTGCAATCCGGGTCCGGTCACACCGGATTCGACATTCAATTCAAGGAGGCGGCGG
CAAGGTCGCCATGACCGACC

Downstream 100 bases:

>100_bases
CGCCAGCCACACTTCTTATCGTGGAAGACCAGGCGGTCGTCGCGGCCGATCTGGGGGACCGCCTGGTACGCCATGGCTAC
AAGGTGTGCGGCGTGGCCGC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MEQVLNKIRVLVVEDEIVVSEDLQQRLSGLGYEITGAADTAAAAIRLAASQRPDVALMDIMLHGRPEGIDAAEHLRGELD
IPVIYLTAHSDTATLHRARFTDPSGYIVKPFDDQQLRVAIELAPFRHEMERKARRVARWMTATLTSIGDAVIATNTHSEI
LLLNPAAEKLTGWTQDEATGKPSGEVVRLVNQKTRQPLEDPATRALRDGLVVRLDPDTVLITREGGERFVDDSASPITDE
TGKVLGAVVVLVDATGRVAAQNRVDTLTRQVKGLLAEKDNYELKGAELEAFATAVSHDLRGPLQAIAGFSELLARSQRER
LDASGQLFLDRVHASALQMGCMVEDYLGFLKSNREQTLSVTELDLKHLAHAVFAELALVPGQKPAQFVCEELPRAWGDEA
MLRQVLVNLIGNALKYSAQREHPMVEVGAIAGEEAGEDCHTFFVRDNGAGLDLANAAKLFEPFQRFHSTAEFPGTGVGLA
IVKRIVERHGGRMLAESQPDAGATFFFTLPSKAPGMTAALQ

Sequences:

>Translated_521_residues
MEQVLNKIRVLVVEDEIVVSEDLQQRLSGLGYEITGAADTAAAAIRLAASQRPDVALMDIMLHGRPEGIDAAEHLRGELD
IPVIYLTAHSDTATLHRARFTDPSGYIVKPFDDQQLRVAIELAPFRHEMERKARRVARWMTATLTSIGDAVIATNTHSEI
LLLNPAAEKLTGWTQDEATGKPSGEVVRLVNQKTRQPLEDPATRALRDGLVVRLDPDTVLITREGGERFVDDSASPITDE
TGKVLGAVVVLVDATGRVAAQNRVDTLTRQVKGLLAEKDNYELKGAELEAFATAVSHDLRGPLQAIAGFSELLARSQRER
LDASGQLFLDRVHASALQMGCMVEDYLGFLKSNREQTLSVTELDLKHLAHAVFAELALVPGQKPAQFVCEELPRAWGDEA
MLRQVLVNLIGNALKYSAQREHPMVEVGAIAGEEAGEDCHTFFVRDNGAGLDLANAAKLFEPFQRFHSTAEFPGTGVGLA
IVKRIVERHGGRMLAESQPDAGATFFFTLPSKAPGMTAALQ
>Mature_521_residues
MEQVLNKIRVLVVEDEIVVSEDLQQRLSGLGYEITGAADTAAAAIRLAASQRPDVALMDIMLHGRPEGIDAAEHLRGELD
IPVIYLTAHSDTATLHRARFTDPSGYIVKPFDDQQLRVAIELAPFRHEMERKARRVARWMTATLTSIGDAVIATNTHSEI
LLLNPAAEKLTGWTQDEATGKPSGEVVRLVNQKTRQPLEDPATRALRDGLVVRLDPDTVLITREGGERFVDDSASPITDE
TGKVLGAVVVLVDATGRVAAQNRVDTLTRQVKGLLAEKDNYELKGAELEAFATAVSHDLRGPLQAIAGFSELLARSQRER
LDASGQLFLDRVHASALQMGCMVEDYLGFLKSNREQTLSVTELDLKHLAHAVFAELALVPGQKPAQFVCEELPRAWGDEA
MLRQVLVNLIGNALKYSAQREHPMVEVGAIAGEEAGEDCHTFFVRDNGAGLDLANAAKLFEPFQRFHSTAEFPGTGVGLA
IVKRIVERHGGRMLAESQPDAGATFFFTLPSKAPGMTAALQ

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=26.8096514745308, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=31.0924369747899, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789149, Length=275, Percent_Identity=27.6363636363636, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=311, Percent_Identity=28.9389067524116, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=28.5067873303167, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=31.4655172413793, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=30.9917355371901, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788381, Length=113, Percent_Identity=36.283185840708, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=26.271186440678, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=245, Percent_Identity=26.1224489795918, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=253, Percent_Identity=28.0632411067194, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56766; Mature: 56766

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVLNKIRVLVVEDEIVVSEDLQQRLSGLGYEITGAADTAAAAIRLAASQRPDVALMDI
CHHHHHHHEEEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEEHH
MLHGRPEGIDAAEHLRGELDIPVIYLTAHSDTATLHRARFTDPSGYIVKPFDDQQLRVAI
HCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCEECCCCCCEEEEEE
ELAPFRHEMERKARRVARWMTATLTSIGDAVIATNTHSEILLLNPAAEKLTGWTQDEATG
EECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCHHHHCCCCCCCCCC
KPSGEVVRLVNQKTRQPLEDPATRALRDGLVVRLDPDTVLITREGGERFVDDSASPITDE
CCCHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCEEEEECCCCCHHCCCCCCCCCCH
TGKVLGAVVVLVDATGRVAAQNRVDTLTRQVKGLLAEKDNYELKGAELEAFATAVSHDLR
HHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHC
GPLQAIAGFSELLARSQRERLDASGQLFLDRVHASALQMGCMVEDYLGFLKSNREQTLSV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEH
TELDLKHLAHAVFAELALVPGQKPAQFVCEELPRAWGDEAMLRQVLVNLIGNALKYSAQR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHC
EHPMVEVGAIAGEEAGEDCHTFFVRDNGAGLDLANAAKLFEPFQRFHSTAEFPGTGVGLA
CCCCEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IVKRIVERHGGRMLAESQPDAGATFFFTLPSKAPGMTAALQ
HHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEQVLNKIRVLVVEDEIVVSEDLQQRLSGLGYEITGAADTAAAAIRLAASQRPDVALMDI
CHHHHHHHEEEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEEHH
MLHGRPEGIDAAEHLRGELDIPVIYLTAHSDTATLHRARFTDPSGYIVKPFDDQQLRVAI
HCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCEECCCCCCEEEEEE
ELAPFRHEMERKARRVARWMTATLTSIGDAVIATNTHSEILLLNPAAEKLTGWTQDEATG
EECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCHHHHCCCCCCCCCC
KPSGEVVRLVNQKTRQPLEDPATRALRDGLVVRLDPDTVLITREGGERFVDDSASPITDE
CCCHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCEEEEECCCCCHHCCCCCCCCCCH
TGKVLGAVVVLVDATGRVAAQNRVDTLTRQVKGLLAEKDNYELKGAELEAFATAVSHDLR
HHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHC
GPLQAIAGFSELLARSQRERLDASGQLFLDRVHASALQMGCMVEDYLGFLKSNREQTLSV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEH
TELDLKHLAHAVFAELALVPGQKPAQFVCEELPRAWGDEAMLRQVLVNLIGNALKYSAQR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHC
EHPMVEVGAIAGEEAGEDCHTFFVRDNGAGLDLANAAKLFEPFQRFHSTAEFPGTGVGLA
CCCCEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IVKRIVERHGGRMLAESQPDAGATFFFTLPSKAPGMTAALQ
HHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]