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The map label for this gene is hmrR2 [H]

Identifier: 91789349

GI number: 91789349

Start: 3696487

End: 3696888

Strand: Reverse

Name: hmrR2 [H]

Synonym: Bpro_3495

Alternate gene names: 91789349

Gene position: 3696888-3696487 (Counterclockwise)

Preceding gene: 91789350

Following gene: 91789348

Centisome position: 71.09

GC content: 64.93

Gene sequence:

>402_bases
ATGAACGCGCAGCGGTTCAACATAGGCCAGGCGGCCGCACGCTCCGGCGTGACGGCCAAGATGATCCGTTACTACGAATC
CATGGGCTTGCTGTCCCCCGTGGCCCGCACAGAGGCCGGCTACCGGCAGTACGGGGACAGCGAAGTCCACACGCTGCGCT
TCGTTGGCCGCGCGCGGAACCTCGGCTTTGGCATGGACGAGATCGCCGAGTTGCTCAAGCTCTGGCAGAACCGTCACCGG
GCGAGCGCCGATGTCAGACGCATCGCTCTGGTCCACATCGCCAACCTGGAGCGCCGAGTGAGCCAGATGGTGTCGATGAA
GCACACGATCGAGGTCTTGGCCGCGTCCTGTCATGGCGACGAGCGGCCAGCCTGTCCGATCCTCGATGAGCTCGCCGAGT
GA

Upstream 100 bases:

>100_bases
ACTGGAAAGGAGATCGACCATGATGTACAACACCGCACCACGGCAAGAACGGGCCGCCAGCAAGCCGGCAGGATACGGTC
GTCACCGAACGCCGGCGCCG

Downstream 100 bases:

>100_bases
GCGAGCGTCGGTGGGAGGTGGGTCCACAACCGATAAACAAGGCGTCATCCGTGCCCGCCCATCCGGAACAAGAAGCGTCC
ATCGGACGGCTGCCCTTGAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MNAQRFNIGQAAARSGVTAKMIRYYESMGLLSPVARTEAGYRQYGDSEVHTLRFVGRARNLGFGMDEIAELLKLWQNRHR
ASADVRRIALVHIANLERRVSQMVSMKHTIEVLAASCHGDERPACPILDELAE

Sequences:

>Translated_133_residues
MNAQRFNIGQAAARSGVTAKMIRYYESMGLLSPVARTEAGYRQYGDSEVHTLRFVGRARNLGFGMDEIAELLKLWQNRHR
ASADVRRIALVHIANLERRVSQMVSMKHTIEVLAASCHGDERPACPILDELAE
>Mature_133_residues
MNAQRFNIGQAAARSGVTAKMIRYYESMGLLSPVARTEAGYRQYGDSEVHTLRFVGRARNLGFGMDEIAELLKLWQNRHR
ASADVRRIALVHIANLERRVSQMVSMKHTIEVLAASCHGDERPACPILDELAE

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=38.5826771653543, Blast_Score=107, Evalue=2e-25,
Organism=Escherichia coli, GI1789687, Length=131, Percent_Identity=31.2977099236641, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14939; Mature: 14939

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQRFNIGQAAARSGVTAKMIRYYESMGLLSPVARTEAGYRQYGDSEVHTLRFVGRARN
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
LGFGMDEIAELLKLWQNRHRASADVRRIALVHIANLERRVSQMVSMKHTIEVLAASCHGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ERPACPILDELAE
CCCCCCHHHHHCC
>Mature Secondary Structure
MNAQRFNIGQAAARSGVTAKMIRYYESMGLLSPVARTEAGYRQYGDSEVHTLRFVGRARN
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
LGFGMDEIAELLKLWQNRHRASADVRRIALVHIANLERRVSQMVSMKHTIEVLAASCHGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ERPACPILDELAE
CCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]