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The map label for this gene is tcyB [H]

Identifier: 91789328

GI number: 91789328

Start: 3676721

End: 3677383

Strand: Direct

Name: tcyB [H]

Synonym: Bpro_3473

Alternate gene names: 91789328

Gene position: 3676721-3677383 (Clockwise)

Preceding gene: 91789327

Following gene: 91789329

Centisome position: 70.7

GC content: 59.88

Gene sequence:

>663_bases
ATGCGGGTTGAGTTGGACTTCATCTCGGTCTTGAGTCAGTGGCCCTTGCTCGCCAAGGGCGTGCTCTGGACAGTGGGCCT
GACGGTCATCTCTGCGATGATGGGCGTGGTAGCGGGCGTGGCGTTTGCCTGGGTCCGCTCGCACGGCGCACCCTGGCTGA
AATGGGGCGTGGGCACCTATGTGGAACTCATTCGCAACACGCCCTTCATCGTGCAGCTCTTCTTTGTATTCTTTGGCCTG
CCTGCGGCGGGCATCAAGCTCTCGCCCGAGGTTGCTTCCATCATCGCGATGGTGATCAACCTGAGCGCCTACGCGACAGA
GATCATTCGTGCCGGGATTGACGCCACGCCCAAAGGGCAAATTGAGGCCGCGATGAGCCTGGCGCTGAACCGCATGCAGA
CCTTTGTGCGCGTGGTCTTGCCGCCCGCACTCCGAAAAGTATGGCCTTCACTCGTCAGCCAGATCATCATCGTGATGCTG
GGCTCGGCGGTGTGCGGGCAAATTTCGACCGAAGAGCTGAGCTACGCCGCCAACCTGATTCAAAGCCGCAACTTTCGCGC
CTTTGAGGCTTACATCGTGGCCACGCTGGTTTACCTGACGCTGGCTGTCGGGGTACGGCAACTGCTCAACTGGCTGGGTC
CGCGTTTCCTTTTTGGCAGATAA

Upstream 100 bases:

>100_bases
TGCAGGGGGCGCCGCTGGTGGCCCGGCAAAGCCGGTTCCACGGCGGCCTGGTAGAGATGCAGAAGAGACTGTCGTTACTT
TTTAGAAGGAGTGAAGCCAG

Downstream 100 bases:

>100_bases
ATAAATATGCCCCCACACTTACTCACTACGTGTAGTTCGCTGCCCCCCGAGGGGTCGCAGGCCTGCTTGGGGCGGCCCGG
CGCGAGGCCTGACCATGGTT

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRVELDFISVLSQWPLLAKGVLWTVGLTVISAMMGVVAGVAFAWVRSHGAPWLKWGVGTYVELIRNTPFIVQLFFVFFGL
PAAGIKLSPEVASIIAMVINLSAYATEIIRAGIDATPKGQIEAAMSLALNRMQTFVRVVLPPALRKVWPSLVSQIIIVML
GSAVCGQISTEELSYAANLIQSRNFRAFEAYIVATLVYLTLAVGVRQLLNWLGPRFLFGR

Sequences:

>Translated_220_residues
MRVELDFISVLSQWPLLAKGVLWTVGLTVISAMMGVVAGVAFAWVRSHGAPWLKWGVGTYVELIRNTPFIVQLFFVFFGL
PAAGIKLSPEVASIIAMVINLSAYATEIIRAGIDATPKGQIEAAMSLALNRMQTFVRVVLPPALRKVWPSLVSQIIIVML
GSAVCGQISTEELSYAANLIQSRNFRAFEAYIVATLVYLTLAVGVRQLLNWLGPRFLFGR
>Mature_220_residues
MRVELDFISVLSQWPLLAKGVLWTVGLTVISAMMGVVAGVAFAWVRSHGAPWLKWGVGTYVELIRNTPFIVQLFFVFFGL
PAAGIKLSPEVASIIAMVINLSAYATEIIRAGIDATPKGQIEAAMSLALNRMQTFVRVVLPPALRKVWPSLVSQIIIVML
GSAVCGQISTEELSYAANLIQSRNFRAFEAYIVATLVYLTLAVGVRQLLNWLGPRFLFGR

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=201, Percent_Identity=34.3283582089552, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787030, Length=216, Percent_Identity=31.4814814814815, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786873, Length=220, Percent_Identity=26.3636363636364, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=25.8928571428571, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787086, Length=181, Percent_Identity=26.5193370165746, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788645, Length=193, Percent_Identity=24.8704663212435, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082239, Length=167, Percent_Identity=31.7365269461078, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786874, Length=190, Percent_Identity=27.3684210526316, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788646, Length=171, Percent_Identity=28.6549707602339, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI48994930, Length=130, Percent_Identity=35.3846153846154, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24111; Mature: 24111

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVELDFISVLSQWPLLAKGVLWTVGLTVISAMMGVVAGVAFAWVRSHGAPWLKWGVGTY
CEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VELIRNTPFIVQLFFVFFGLPAAGIKLSPEVASIIAMVINLSAYATEIIRAGIDATPKGQ
HHHHHCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IEAAMSLALNRMQTFVRVVLPPALRKVWPSLVSQIIIVMLGSAVCGQISTEELSYAANLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRNFRAFEAYIVATLVYLTLAVGVRQLLNWLGPRFLFGR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MRVELDFISVLSQWPLLAKGVLWTVGLTVISAMMGVVAGVAFAWVRSHGAPWLKWGVGTY
CEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VELIRNTPFIVQLFFVFFGLPAAGIKLSPEVASIIAMVINLSAYATEIIRAGIDATPKGQ
HHHHHCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IEAAMSLALNRMQTFVRVVLPPALRKVWPSLVSQIIIVMLGSAVCGQISTEELSYAANLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRNFRAFEAYIVATLVYLTLAVGVRQLLNWLGPRFLFGR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]