Click here to switch to the map view.

The map label for this gene is nodT [H]

Identifier: 91789298

GI number: 91789298

Start: 3645162

End: 3646622

Strand: Reverse

Name: nodT [H]

Synonym: Bpro_3443

Alternate gene names: 91789298

Gene position: 3646622-3645162 (Counterclockwise)

Preceding gene: 91789305

Following gene: 91789297

Centisome position: 70.12

GC content: 63.79

Gene sequence:

>1461_bases
ATGCTGCCTAAACACACCCTTGCCATCTTCATTGTTGCCGGCCTCTCGGCCGGCTGCGCCGTCGGTCCCGACTATGTCAG
GCCCGACACGCCCATGCCGCAACAGTACCTGGGCCAACCAGCGGTCGACCAGCGGCACGCCACTGCCCATGCCGATCTCG
TCACCTGGTGGACGGGTTTCGGTGATCCGCTACTGACTCGATTCGTCACGCTGGCGGTGGAACAGAACCTCGATCTCGCG
CAGGCATCCGCTCGCGTCACCCAGGCGCGCGCGGAGCTTGGGGCGGCAAATGCCGCGTTGCTGCCTTCCGGCAACGTCAG
CGGCCAGGCAGCCAGAGCCTACCAATCCCTTGAAACGCCTCTGGGAAAAGTCTTGAGCGCTAGCCCCGGTTTCGACCGTC
ACGGCAGTTCTTACGAAACCAATCTCGGCGCGAGCTGGGAACTGGATGTATTCGGAGGCTTGCGTCGTGGAAAGGAAGCG
GCACTTGCCGGGTACCAGGCGTCGGAGGCCGGCGCAGCCGCTACCCGGTTGGCTGTGGCGGCACAGACCGCCGACACCTA
CATCATCATTCGTGGGCTGCAAACCCGCCTCGGCGTTGCCCGCGGGCAGGTGCAGACGCAGCAGGAATTGCTATCGACCA
TCAACCTTCTGTATGGGAAGGGGTTGGCGGCCGAACTTCAAGTGAGGCAGGCCGAAGGTGCGCTTGCCCAGGTTCGGGCG
TCCGTGCCGGTTCTTGAGGCGGGTCTGGACGTGGCCATGAACGCGCTTGACGTGATGCTGGGCACGCCACCCGGAACGCA
TCGGATGGAACTGGCCGATGCTGGCGTCATCCCTGCTGCCCCGCAAATCACTGCTGCAGGCTCTCCGGGTGAGCTGCTAA
GGCGCCGCCCTGACCTGATTGTGGCTGAGCGCCGCCTTGCCGCATCGAATGCCCGTATCGGTGTCGCCATTGCCGAGTAC
TACCCCAAACTCTCTCTGAGTGGGCTGATCGGCAGCGCGACATCGGTGTCCGGTGGCAATCTGTTCACCAGCGGCGCGAG
TCAGGCCGCCGGCGTGCTGGGTCTGCGCTGGCGTCTGTTCGACTTTGGCCGCATCAACGCGCAGATCGACCAAGCCAGGG
GCCAGGAGGCCGAGATGCTGGCTGCGTATCGGCTTGCCGTACTGCGGGCAACTGAGGACGTAGAAAACGCCTTTTCGGCC
TTGGTCAAGCGCGAGGAGCAGGCTGTTGTACTTGCCCAGGGAGTGGACTCTCTCGGCCGCGCCCGATCAGCTTCGTTTGC
GGCGTATCAAAAAGGGGTACTCAGTCTGATCGAAGTCTTGCAGGCCGACGACAACCTGCTACGTGCCTCCGATGCGCGAG
CGCAAGCGCAAACGGAATCAGCACGCGCGGCGGTCGCTACCTTCAAAGCGCTCGGCGGCGGTTGGCAACCCCAGGAATCC
AGCGCCGTGGCAATTAGATAG

Upstream 100 bases:

>100_bases
TGTTCATGGTCTGTAGCTTACCTGCATCTAAAGAAATGAACAACGAGTGACCATATTGTATTATAGTCACTTCATCGACT
ACCTGATTCGGAACAAGTCT

Downstream 100 bases:

>100_bases
CCCAACGTTGGGGAAATTGATCCATAAAACTCTGTAGAGATCGATTCATTTCGCCCATCAGGCACCGAAGTCTCTCTGCA
TTTTTGCTCAAGGGTGAAAC

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MLPKHTLAIFIVAGLSAGCAVGPDYVRPDTPMPQQYLGQPAVDQRHATAHADLVTWWTGFGDPLLTRFVTLAVEQNLDLA
QASARVTQARAELGAANAALLPSGNVSGQAARAYQSLETPLGKVLSASPGFDRHGSSYETNLGASWELDVFGGLRRGKEA
ALAGYQASEAGAAATRLAVAAQTADTYIIIRGLQTRLGVARGQVQTQQELLSTINLLYGKGLAAELQVRQAEGALAQVRA
SVPVLEAGLDVAMNALDVMLGTPPGTHRMELADAGVIPAAPQITAAGSPGELLRRRPDLIVAERRLAASNARIGVAIAEY
YPKLSLSGLIGSATSVSGGNLFTSGASQAAGVLGLRWRLFDFGRINAQIDQARGQEAEMLAAYRLAVLRATEDVENAFSA
LVKREEQAVVLAQGVDSLGRARSASFAAYQKGVLSLIEVLQADDNLLRASDARAQAQTESARAAVATFKALGGGWQPQES
SAVAIR

Sequences:

>Translated_486_residues
MLPKHTLAIFIVAGLSAGCAVGPDYVRPDTPMPQQYLGQPAVDQRHATAHADLVTWWTGFGDPLLTRFVTLAVEQNLDLA
QASARVTQARAELGAANAALLPSGNVSGQAARAYQSLETPLGKVLSASPGFDRHGSSYETNLGASWELDVFGGLRRGKEA
ALAGYQASEAGAAATRLAVAAQTADTYIIIRGLQTRLGVARGQVQTQQELLSTINLLYGKGLAAELQVRQAEGALAQVRA
SVPVLEAGLDVAMNALDVMLGTPPGTHRMELADAGVIPAAPQITAAGSPGELLRRRPDLIVAERRLAASNARIGVAIAEY
YPKLSLSGLIGSATSVSGGNLFTSGASQAAGVLGLRWRLFDFGRINAQIDQARGQEAEMLAAYRLAVLRATEDVENAFSA
LVKREEQAVVLAQGVDSLGRARSASFAAYQKGVLSLIEVLQADDNLLRASDARAQAQTESARAAVATFKALGGGWQPQES
SAVAIR
>Mature_486_residues
MLPKHTLAIFIVAGLSAGCAVGPDYVRPDTPMPQQYLGQPAVDQRHATAHADLVTWWTGFGDPLLTRFVTLAVEQNLDLA
QASARVTQARAELGAANAALLPSGNVSGQAARAYQSLETPLGKVLSASPGFDRHGSSYETNLGASWELDVFGGLRRGKEA
ALAGYQASEAGAAATRLAVAAQTADTYIIIRGLQTRLGVARGQVQTQQELLSTINLLYGKGLAAELQVRQAEGALAQVRA
SVPVLEAGLDVAMNALDVMLGTPPGTHRMELADAGVIPAAPQITAAGSPGELLRRRPDLIVAERRLAASNARIGVAIAEY
YPKLSLSGLIGSATSVSGGNLFTSGASQAAGVLGLRWRLFDFGRINAQIDQARGQEAEMLAAYRLAVLRATEDVENAFSA
LVKREEQAVVLAQGVDSLGRARSASFAAYQKGVLSLIEVLQADDNLLRASDARAQAQTESARAAVATFKALGGGWQPQES
SAVAIR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=489, Percent_Identity=26.3803680981595, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI2367348, Length=477, Percent_Identity=25.1572327044025, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50881; Mature: 50881

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKHTLAIFIVAGLSAGCAVGPDYVRPDTPMPQQYLGQPAVDQRHATAHADLVTWWTGF
CCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCC
GDPLLTRFVTLAVEQNLDLAQASARVTQARAELGAANAALLPSGNVSGQAARAYQSLETP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHH
LGKVLSASPGFDRHGSSYETNLGASWELDVFGGLRRGKEAALAGYQASEAGAAATRLAVA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHCCHHCCCHHHHCCCCCCCCCHHHHHHHHH
AQTADTYIIIRGLQTRLGVARGQVQTQQELLSTINLLYGKGLAAELQVRQAEGALAQVRA
EECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHCCHHHHHHH
SVPVLEAGLDVAMNALDVMLGTPPGTHRMELADAGVIPAAPQITAAGSPGELLRRRPDLI
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEECCCCHHHHHCCCCCE
VAERRLAASNARIGVAIAEYYPKLSLSGLIGSATSVSGGNLFTSGASQAAGVLGLRWRLF
EHHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCCCCCCEEECCCHHHCCHHEEEEEEE
DFGRINAQIDQARGQEAEMLAAYRLAVLRATEDVENAFSALVKREEQAVVLAQGVDSLGR
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCHHHHHH
ARSASFAAYQKGVLSLIEVLQADDNLLRASDARAQAQTESARAAVATFKALGGGWQPQES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SAVAIR
CCEECC
>Mature Secondary Structure
MLPKHTLAIFIVAGLSAGCAVGPDYVRPDTPMPQQYLGQPAVDQRHATAHADLVTWWTGF
CCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCC
GDPLLTRFVTLAVEQNLDLAQASARVTQARAELGAANAALLPSGNVSGQAARAYQSLETP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHH
LGKVLSASPGFDRHGSSYETNLGASWELDVFGGLRRGKEAALAGYQASEAGAAATRLAVA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHCCHHCCCHHHHCCCCCCCCCHHHHHHHHH
AQTADTYIIIRGLQTRLGVARGQVQTQQELLSTINLLYGKGLAAELQVRQAEGALAQVRA
EECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHCCHHHHHHH
SVPVLEAGLDVAMNALDVMLGTPPGTHRMELADAGVIPAAPQITAAGSPGELLRRRPDLI
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEECCCCHHHHHCCCCCE
VAERRLAASNARIGVAIAEYYPKLSLSGLIGSATSVSGGNLFTSGASQAAGVLGLRWRLF
EHHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCCCCCCEEECCCHHHCCHHEEEEEEE
DFGRINAQIDQARGQEAEMLAAYRLAVLRATEDVENAFSALVKREEQAVVLAQGVDSLGR
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCHHHHHH
ARSASFAAYQKGVLSLIEVLQADDNLLRASDARAQAQTESARAAVATFKALGGGWQPQES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SAVAIR
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]