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The map label for this gene is gcp

Identifier: 91789125

GI number: 91789125

Start: 3455683

End: 3456726

Strand: Reverse

Name: gcp

Synonym: Bpro_3265

Alternate gene names: 91789125

Gene position: 3456726-3455683 (Counterclockwise)

Preceding gene: 91789134

Following gene: 91789123

Centisome position: 66.47

GC content: 66.67

Gene sequence:

>1044_bases
ATGCTAGTCCTTGGAATTGAGTCGAGTTGCGATGAAACGGGTGTGGCGCTGGTGGATGCCGGCGGCAGCGAGGTGCCGCG
CCTGCTCTCGCATGCCTTGTTCAGCCAGATCCAGATGCACCAGGCGTATGGCGGCGTGGTGCCCGAGCTGGCCAGTCGTG
ACCACATACGGCGGGTCCTGCCCTTGACGCGCCAGGTCATGGCGCAGGCCGGGCGGTCGCTGGCGCAGGTGGATGTGGTG
GCTTACACGCGCGGGCCGGGGCTGGCTGGCGCACTGCTGGTGGGCGCCGGCGTTGCCTGCGCCCTGGCGGCCGCGCTGGG
CAAGCCGGTGATGGGCGTGCACCATCTGGAGGGGCATTTGCTGTCGCCGTTCCTGAGTGCCGATCCGCCGGTGTTTCCGT
TTGTGGCCCTGCTGGTTTCCGGCGGGCACACCCAACTGATGCGGGTGGACCGTGTCGGCAGTTACGAGCTGCTGGGAGAA
ACCATCGATGACGCGGCGGGCGAGGCCTTTGACAAGTCGGCAAAGCTGATGGGTTTGCCCTATCCCGGGGGGCCGCATCT
GGCTGACCTGGCACGGCAGGGCGATGGCACCGCCTTCAAATTGCCCCGACCCTTGCTGCACAGCGGAGACCTCGATTTTT
CGTTCGCGGGGCTGAAAACCGCGGTGCTGACCCAAGCCAAAAAACTGGGTCCTGAACTGGAAAACCGCAAAGCGGATCTG
GCTGCGGCCACCCAGGCGGCCATCGTGGATGTACTGGTCAAGAAATCGCTGGCCGCCATGGCGCAAACCGGCCTGAAGCG
ACTCGTCGTTGCGGGCGGCGTGGGGGCCAATGCCCTGCTGCGCAGCCAGCTGAATGCGGCCTGCCAGCAACGCGGCATCC
GCGTGCATTACCCGGAGCTGCACCTGTGCACGGACAACGGCGCGATGATCGCGCTGGCCGCCGGCATGCGCCTGCAGGCC
GGCCTGGAAACGCTGCAGCGCGGCTACACCTTTGACGTGAAGCCGCGCTGGAGTTTGACCCCCACGGTCGCTCGCTCCGC
GTAG

Upstream 100 bases:

>100_bases
TGCAAGATTCGCGCCAGATTGCGGGCCGGCTGTTCCCGTTTTCGCGACAGGAAGGTCCTTCTCCAGGCCCGGGAAAGCGC
TCAACCTTACACTTGGGGCG

Downstream 100 bases:

>100_bases
CTCCCTGCCCCCCGAGGGGGCCGCTGCGCCTGCGGCCCGGCAAAGCCGGTTCCGCGGCCCTGGCTGGCATAACTTCCCGC
CCCTCGTGGGGACCGCCGGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVLPLTRQVMAQAGRSLAQVDVV
AYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHLLSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGE
TIDDAAGEAFDKSAKLMGLPYPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADL
AAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPELHLCTDNGAMIALAAGMRLQA
GLETLQRGYTFDVKPRWSLTPTVARSA

Sequences:

>Translated_347_residues
MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVLPLTRQVMAQAGRSLAQVDVV
AYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHLLSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGE
TIDDAAGEAFDKSAKLMGLPYPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADL
AAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPELHLCTDNGAMIALAAGMRLQA
GLETLQRGYTFDVKPRWSLTPTVARSA
>Mature_347_residues
MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVLPLTRQVMAQAGRSLAQVDVV
AYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHLLSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGE
TIDDAAGEAFDKSAKLMGLPYPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADL
AAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPELHLCTDNGAMIALAAGMRLQA
GLETLQRGYTFDVKPRWSLTPTVARSA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=367, Percent_Identity=32.425068119891, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI8923380, Length=348, Percent_Identity=30.4597701149425, Blast_Score=138, Evalue=6e-33,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=53.6873156342183, Blast_Score=342, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI71995670, Length=351, Percent_Identity=31.9088319088319, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17557464, Length=339, Percent_Identity=30.0884955752212, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=372, Percent_Identity=31.989247311828, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322891, Length=354, Percent_Identity=26.8361581920904, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI20129063, Length=358, Percent_Identity=34.3575418994413, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21357207, Length=358, Percent_Identity=30.1675977653631, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_POLSJ (Q127W3)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550077.1
- STRING:   Q127W3
- MEROPS:   M22.001
- GeneID:   4014074
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3265
- NMPDR:   fig|296591.1.peg.1205
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q127W3
- ProtClustDB:   PRK09604
- BioCyc:   PSP296591:BPRO_3265-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36319; Mature: 36319

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVL
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
PLTRQVMAQAGRSLAQVDVVAYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHL
HHHHHHHHHHCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHH
LSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGETIDDAAGEAFDKSAKLMGLP
HCHHHCCCCCHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECC
YPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADL
CCCCCHHHHHHHCCCCCEEECCCHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHCCHHHH
AAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCEE
HLCTDNGAMIALAAGMRLQAGLETLQRGYTFDVKPRWSLTPTVARSA
EEECCCCCEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCHHHCCC
>Mature Secondary Structure
MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVL
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
PLTRQVMAQAGRSLAQVDVVAYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHL
HHHHHHHHHHCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHH
LSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGETIDDAAGEAFDKSAKLMGLP
HCHHHCCCCCHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEECC
YPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADL
CCCCCHHHHHHHCCCCCEEECCCHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHCCHHHH
AAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCEE
HLCTDNGAMIALAAGMRLQAGLETLQRGYTFDVKPRWSLTPTVARSA
EEECCCCCEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA