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The map label for this gene is slyD [H]

Identifier: 91789036

GI number: 91789036

Start: 3361108

End: 3361632

Strand: Direct

Name: slyD [H]

Synonym: Bpro_3176

Alternate gene names: 91789036

Gene position: 3361108-3361632 (Clockwise)

Preceding gene: 91789033

Following gene: 91789041

Centisome position: 64.63

GC content: 56.0

Gene sequence:

>525_bases
ATGAAAATCACCCCGCAATGCGTCGTAGCCCTGACATGGACGCTGAAAGACACCCTGGGCGATGTGCTCGATGAACTGGA
CGAGCCGGTCGAGTTTTTAGTGGGCGGCAATGATCTGCTGATCAAAATTGAAGAGGCCCTGCAGGGCCACGAGGCCGGCG
ACAAGCTTGAATTGCATCTGGAGCCCGAAAACACCTTCGGCGACTATGACGAAAACCTGGTTTTCCTGGAAGCCCGCAAC
ATTTTCCCCGCAGAACTGGAAGAAGGCATGACCTTCGACGGCGCAGCGCTACCGGCCGGCGCCAACGGGAAAATTCCGCA
CGACCACATTTACACCGTAACGGAAATTTATCCTGAGCATGTGGTGCTGGATGGCAATCATCCCCTGGCCGGCATTGCGA
TCCGGTTGGCGATGAAAGTGGAGTCTGTGCGCGAGGCCACCGCGCAGGAAATTGGACGCGACTCTCTCGGTACGGGTTTT
TTCAAACTGGAATCGCTGACGAGCGGCAACGACACATTGCATTGA

Upstream 100 bases:

>100_bases
AGAAGCGGCTTTTTTTGCCAGTACTGGCGCATGAATCGGGCCGGGCTCAAGCCGGCAAGAAGGTCTAGAGCGTGATTTAC
ATCCATGGGACAATTGTCGG

Downstream 100 bases:

>100_bases
TCCACTCAGGGTGAACGCGAGTTGCAGAGCGGTGCAGCAAATGCTGCCACCGCTCCTACTCTTACCTTTATCTAAACCTA
AACCCTCACCCGCCGTGAAG

Product: putative fkbp-type peptidyl-prolyl cis-trans isomerase (rotamase) protein

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKITPQCVVALTWTLKDTLGDVLDELDEPVEFLVGGNDLLIKIEEALQGHEAGDKLELHLEPENTFGDYDENLVFLEARN
IFPAELEEGMTFDGAALPAGANGKIPHDHIYTVTEIYPEHVVLDGNHPLAGIAIRLAMKVESVREATAQEIGRDSLGTGF
FKLESLTSGNDTLH

Sequences:

>Translated_174_residues
MKITPQCVVALTWTLKDTLGDVLDELDEPVEFLVGGNDLLIKIEEALQGHEAGDKLELHLEPENTFGDYDENLVFLEARN
IFPAELEEGMTFDGAALPAGANGKIPHDHIYTVTEIYPEHVVLDGNHPLAGIAIRLAMKVESVREATAQEIGRDSLGTGF
FKLESLTSGNDTLH
>Mature_174_residues
MKITPQCVVALTWTLKDTLGDVLDELDEPVEFLVGGNDLLIKIEEALQGHEAGDKLELHLEPENTFGDYDENLVFLEARN
IFPAELEEGMTFDGAALPAGANGKIPHDHIYTVTEIYPEHVVLDGNHPLAGIAIRLAMKVESVREATAQEIGRDSLGTGF
FKLESLTSGNDTLH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=156, Percent_Identity=34.6153846153846, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19036; Mature: 19036

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITPQCVVALTWTLKDTLGDVLDELDEPVEFLVGGNDLLIKIEEALQGHEAGDKLELHL
CCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHCCCCCCCEEEEEE
EPENTFGDYDENLVFLEARNIFPAELEEGMTFDGAALPAGANGKIPHDHIYTVTEIYPEH
CCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHEEECCCE
VVLDGNHPLAGIAIRLAMKVESVREATAQEIGRDSLGTGFFKLESLTSGNDTLH
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKITPQCVVALTWTLKDTLGDVLDELDEPVEFLVGGNDLLIKIEEALQGHEAGDKLELHL
CCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHCCCCCCCEEEEEE
EPENTFGDYDENLVFLEARNIFPAELEEGMTFDGAALPAGANGKIPHDHIYTVTEIYPEH
CCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHEEECCCE
VVLDGNHPLAGIAIRLAMKVESVREATAQEIGRDSLGTGFFKLESLTSGNDTLH
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]