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The map label for this gene is dapA [H]

Identifier: 91789030

GI number: 91789030

Start: 3355805

End: 3356776

Strand: Direct

Name: dapA [H]

Synonym: Bpro_3170

Alternate gene names: 91789030

Gene position: 3355805-3356776 (Clockwise)

Preceding gene: 91789029

Following gene: 91789031

Centisome position: 64.53

GC content: 62.96

Gene sequence:

>972_bases
ATGCAGGATTGGCTCTTCGGGTCGGCAATCTACTTTTCACGATTGTTTCCAGACCACTCCCAGGGCCGCGAACCTACAGA
CCAAGACATGAAACCCATTACTGGCAGCATCGTTGCACTGGCAACACCCTTGCATGATGACGGCAGCGTAGATTACCCCA
CCCTGCGCAAACTGGTGGACTGGCACATCGCCGAAGGGACCGACTGCATAGGCGTGGTCGGCACCACCGGCGAATCCCCG
ACCGTCAACGTCGAAGAGCACTGCGAAATCATCCGCGTCTCGGTGGAGCAGGCGAAAAAGCGCGTGCCCATCATGGCCGG
CTGCGGCGCCAATTCCACCGCCGAGGCGATCGAGCTCGCCAGGTTTGCCAAGCAGGTGGGCGCCGACTGCCAGCTGCAAG
TCGTCCCCTATTACAACAAGCCCACCCAGGAAGGCCAGTACCGGCATTTCAAGGCGATCGCCGAGGCTGTCGGTGACCTG
CCCATCGTGCTGTACAACGTGCCCGGCCGCACCGTAGCCGATATGGCGCATGCCACCGTGCTGCGCCTGGCCCAGGTGCC
CGGCATTGTCGGCATCAAGGAAGCCACCGGCAACATCGAGCGCGCGCAGTGGCTGATCAAGGAAGTCCCCCAGGGGTTTG
CCGTGTACTCGGGTGATGATCCGACCGCCGTGGCGCTGATGCTGTGCGGTGGACAAGGCAACGTCAGCGTGACGGCCAAC
ATCGCGCCACGCCTGATGCACGAGTTGTGCGTGGCGGCTGTAGCGGGAGACGCCAGGCGGGCCATGGAACTGCAGTTCAA
ACTGCTGCCTCTGCACAGAAACCTTTTTGTCGAAGCCAACCCGATTCCTGTCAAGTGGGCGATGGCCCGGATGGGACTGT
GCGGCGGCACGCTGCGGCTGCCGATGACGCCGCTTGACACCTCCAACGAAGCTGCCGTGGAAGGCGCCCTGCGCGCCTGC
GGCCTGATCTGA

Upstream 100 bases:

>100_bases
CGCCATCCACGAACCCGAAAACCATCCGGGTTTGCCCGGGGTCCTGCAACCCCACACCCCAGTCCCCCCACGCTACAGAC
TGGTCTAGCCTCTGGGTAGA

Downstream 100 bases:

>100_bases
TTTTTAAGGGAACCCCCGTGAAGAACTTGCCAAAACGCCCTGCCTTTGCAACCGCCCAAACCGCGCTAACCATATCTGCA
CTGGTTGCCGTGGGTCTGCT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQDWLFGSAIYFSRLFPDHSQGREPTDQDMKPITGSIVALATPLHDDGSVDYPTLRKLVDWHIAEGTDCIGVVGTTGESP
TVNVEEHCEIIRVSVEQAKKRVPIMAGCGANSTAEAIELARFAKQVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVGDL
PIVLYNVPGRTVADMAHATVLRLAQVPGIVGIKEATGNIERAQWLIKEVPQGFAVYSGDDPTAVALMLCGGQGNVSVTAN
IAPRLMHELCVAAVAGDARRAMELQFKLLPLHRNLFVEANPIPVKWAMARMGLCGGTLRLPMTPLDTSNEAAVEGALRAC
GLI

Sequences:

>Translated_323_residues
MQDWLFGSAIYFSRLFPDHSQGREPTDQDMKPITGSIVALATPLHDDGSVDYPTLRKLVDWHIAEGTDCIGVVGTTGESP
TVNVEEHCEIIRVSVEQAKKRVPIMAGCGANSTAEAIELARFAKQVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVGDL
PIVLYNVPGRTVADMAHATVLRLAQVPGIVGIKEATGNIERAQWLIKEVPQGFAVYSGDDPTAVALMLCGGQGNVSVTAN
IAPRLMHELCVAAVAGDARRAMELQFKLLPLHRNLFVEANPIPVKWAMARMGLCGGTLRLPMTPLDTSNEAAVEGALRAC
GLI
>Mature_323_residues
MQDWLFGSAIYFSRLFPDHSQGREPTDQDMKPITGSIVALATPLHDDGSVDYPTLRKLVDWHIAEGTDCIGVVGTTGESP
TVNVEEHCEIIRVSVEQAKKRVPIMAGCGANSTAEAIELARFAKQVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVGDL
PIVLYNVPGRTVADMAHATVLRLAQVPGIVGIKEATGNIERAQWLIKEVPQGFAVYSGDDPTAVALMLCGGQGNVSVTAN
IAPRLMHELCVAAVAGDARRAMELQFKLLPLHRNLFVEANPIPVKWAMARMGLCGGTLRLPMTPLDTSNEAAVEGALRAC
GLI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=288, Percent_Identity=28.4722222222222, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI13540533, Length=281, Percent_Identity=27.4021352313167, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=49.6575342465753, Blast_Score=280, Evalue=8e-77,
Organism=Escherichia coli, GI87082415, Length=287, Percent_Identity=34.1463414634146, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786463, Length=287, Percent_Identity=31.0104529616725, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789620, Length=233, Percent_Identity=29.6137339055794, Blast_Score=121, Evalue=5e-29,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34810; Mature: 34810

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDWLFGSAIYFSRLFPDHSQGREPTDQDMKPITGSIVALATPLHDDGSVDYPTLRKLVD
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
WHIAEGTDCIGVVGTTGESPTVNVEEHCEIIRVSVEQAKKRVPIMAGCGANSTAEAIELA
HHHCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
RFAKQVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVGDLPIVLYNVPGRTVADMAHATV
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
LRLAQVPGIVGIKEATGNIERAQWLIKEVPQGFAVYSGDDPTAVALMLCGGQGNVSVTAN
HHHHHCCCCEEEHHCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCEEEEEC
IAPRLMHELCVAAVAGDARRAMELQFKLLPLHRNLFVEANPIPVKWAMARMGLCGGTLRL
CHHHHHHHHHHHHHHCCHHHHEEEEEEEEEECCCEEEECCCCCHHHHHHHHCCCCCEEEC
PMTPLDTSNEAAVEGALRACGLI
CCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDWLFGSAIYFSRLFPDHSQGREPTDQDMKPITGSIVALATPLHDDGSVDYPTLRKLVD
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
WHIAEGTDCIGVVGTTGESPTVNVEEHCEIIRVSVEQAKKRVPIMAGCGANSTAEAIELA
HHHCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
RFAKQVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVGDLPIVLYNVPGRTVADMAHATV
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
LRLAQVPGIVGIKEATGNIERAQWLIKEVPQGFAVYSGDDPTAVALMLCGGQGNVSVTAN
HHHHHCCCCEEEHHCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCEEEEEC
IAPRLMHELCVAAVAGDARRAMELQFKLLPLHRNLFVEANPIPVKWAMARMGLCGGTLRL
CHHHHHHHHHHHHHHCCHHHHEEEEEEEEEECCCEEEECCCCCHHHHHHHHCCCCCEEEC
PMTPLDTSNEAAVEGALRACGLI
CCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA