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The map label for this gene is mdtA [H]

Identifier: 91788687

GI number: 91788687

Start: 2971888

End: 2973282

Strand: Direct

Name: mdtA [H]

Synonym: Bpro_2826

Alternate gene names: 91788687

Gene position: 2971888-2973282 (Clockwise)

Preceding gene: 91788686

Following gene: 91788688

Centisome position: 57.15

GC content: 67.81

Gene sequence:

>1395_bases
ATGGACCCGAGAGCCGCAACGCCGCACACCGGCGCCAATCCACCACCCGGTAAACGATTGAGCCGCCGTGCATCCATCAT
CGGCGCCGTGATCGCCATCCTGGCACTGGCCGGTACCGGCTGGCTGGCCTGGCACCTGACACATCCTTCGCCGGAAGCCG
GCAGTACAGCGGCAGGACCTGGTGGACCAGGAGCCCCTGCCGGACGGCGTGGCCCGCCAGCCACCACCGTGGGTGTGGCC
ACTGCCGAGCGGGCCAGCATTCCAGTGATTCTGGAGGCGCTGGGTACCGTCACCCCGCAGGCTACCGTCAAGGTGCGCCC
CCAGGTGTCCGGTGTCATGGAAAAAGTACTGTTCAAGGAAGGCCAGATGGTCAAGGCCGGCGATCTGCTGGCCACCATTG
ACCCGCGCCAATTTGAAATGGCGCTGATGCAGGCTTCCGGCCAGCGCCAGCGTGACGAAGCGCAGCTCGACAGCGCCCGC
GTCACCCTGCAGCGCTTCAAGACCCTGCTGGAGCAGGACTCGATTGCCCGCCAGGAAGTCGACACCCAGGCCGCGCTGGT
CAAGCAGCTGGAAGGCACGGTCGTCATTGACAAGGCCTCCGAGGGCACGGCCCGCCTTAACCTGGGCTACACCCGGGTGG
TAGCGCCAATCAGTGGCCGGGTGGGCCTGCGCACGGTGGACGTCGGCAATGTGGTGAGCAGCAGCGACGCCAATGGCATC
GCGCTGATCACCCAGGTCAGCCCGATTGACGTGGTGTTTTCCATTCCGCAGGACCAGGTCGGCGAGCTGCAGCAAAGCGC
CAGCGGCAGTGCGGCCATGAAGGTCACCGCGTTCGACCGGACGCGCTCCACCACGCTGGACACCGGTATGTTTGCCTCGC
TGGACAACCAGGTCGACACGCAGACCGGCACGGTCAAGGCCAAGGCGCGCTTTGCCAACAGCAAGCTGGCGCTCTTCCCC
AGCCAGTTTGTCAATGTGCAGCTGCTGGTCAGGACCATTGACAACGCTGTGGTGGTGCCGGTGACGGCACTGCGCCACGG
CAGCACCGGCGACTATGTGTATGTGGTCAATACCGCCGAGCGCACCGTGAGCCTGCGGCCCGTGCAGCGCGGCCAGGCCA
CGGTCGACAAGATAGTGATCGCATCCGGCCTGCAGCCCGGCGAGCGCGTCATCACGGAAGGCGCCGACCGCCTGAAGGAC
GGCGCCAAGGTGATCTTGCCCGGTGACCAGCCCGGCGGCGGCGGCGCCGGATCTACCGGCAAGCGCCAGCGGCCCGGCGG
GCCTGCTTCCGCGCCGGCAGCTGGGGCCTCCAGCCCGGCGGCAGCCGATGCCCCCGCGGCCGATGCATCCAGCCCACGGC
GGCGGCGCCGCGCTTCGCAAGCTGAGGGCTCATGA

Upstream 100 bases:

>100_bases
TGCAACCCAAGCCTGGCATGACGCCGATACCCCCATCAAACACCATAAACAATAAGTGCCGCGGCAATCCCGTCGTCGTG
GCGGGCAACAAGGACAGCTG

Downstream 100 bases:

>100_bases
CAGGCGTGTATTGCTCCTTTCCCTGCCCGGGGAAGGTCGAGGCGGGAGTTGCTGGCTGTGGTAGCGCTGCTGGCCCCCAC
TCACGCCCTGCCCCGGCAGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MDPRAATPHTGANPPPGKRLSRRASIIGAVIAILALAGTGWLAWHLTHPSPEAGSTAAGPGGPGAPAGRRGPPATTVGVA
TAERASIPVILEALGTVTPQATVKVRPQVSGVMEKVLFKEGQMVKAGDLLATIDPRQFEMALMQASGQRQRDEAQLDSAR
VTLQRFKTLLEQDSIARQEVDTQAALVKQLEGTVVIDKASEGTARLNLGYTRVVAPISGRVGLRTVDVGNVVSSSDANGI
ALITQVSPIDVVFSIPQDQVGELQQSASGSAAMKVTAFDRTRSTTLDTGMFASLDNQVDTQTGTVKAKARFANSKLALFP
SQFVNVQLLVRTIDNAVVVPVTALRHGSTGDYVYVVNTAERTVSLRPVQRGQATVDKIVIASGLQPGERVITEGADRLKD
GAKVILPGDQPGGGGAGSTGKRQRPGGPASAPAAGASSPAAADAPAADASSPRRRRRASQAEGS

Sequences:

>Translated_464_residues
MDPRAATPHTGANPPPGKRLSRRASIIGAVIAILALAGTGWLAWHLTHPSPEAGSTAAGPGGPGAPAGRRGPPATTVGVA
TAERASIPVILEALGTVTPQATVKVRPQVSGVMEKVLFKEGQMVKAGDLLATIDPRQFEMALMQASGQRQRDEAQLDSAR
VTLQRFKTLLEQDSIARQEVDTQAALVKQLEGTVVIDKASEGTARLNLGYTRVVAPISGRVGLRTVDVGNVVSSSDANGI
ALITQVSPIDVVFSIPQDQVGELQQSASGSAAMKVTAFDRTRSTTLDTGMFASLDNQVDTQTGTVKAKARFANSKLALFP
SQFVNVQLLVRTIDNAVVVPVTALRHGSTGDYVYVVNTAERTVSLRPVQRGQATVDKIVIASGLQPGERVITEGADRLKD
GAKVILPGDQPGGGGAGSTGKRQRPGGPASAPAAGASSPAAADAPAADASSPRRRRRASQAEGS
>Mature_464_residues
MDPRAATPHTGANPPPGKRLSRRASIIGAVIAILALAGTGWLAWHLTHPSPEAGSTAAGPGGPGAPAGRRGPPATTVGVA
TAERASIPVILEALGTVTPQATVKVRPQVSGVMEKVLFKEGQMVKAGDLLATIDPRQFEMALMQASGQRQRDEAQLDSAR
VTLQRFKTLLEQDSIARQEVDTQAALVKQLEGTVVIDKASEGTARLNLGYTRVVAPISGRVGLRTVDVGNVVSSSDANGI
ALITQVSPIDVVFSIPQDQVGELQQSASGSAAMKVTAFDRTRSTTLDTGMFASLDNQVDTQTGTVKAKARFANSKLALFP
SQFVNVQLLVRTIDNAVVVPVTALRHGSTGDYVYVVNTAERTVSLRPVQRGQATVDKIVIASGLQPGERVITEGADRLKD
GAKVILPGDQPGGGGAGSTGKRQRPGGPASAPAAGASSPAAADAPAADASSPRRRRRASQAEGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=367, Percent_Identity=46.3215258855586, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1789929, Length=337, Percent_Identity=30.8605341246291, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786668, Length=336, Percent_Identity=31.8452380952381, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789665, Length=361, Percent_Identity=30.4709141274238, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081796, Length=178, Percent_Identity=34.2696629213483, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081951, Length=213, Percent_Identity=29.1079812206573, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47989; Mature: 47989

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPRAATPHTGANPPPGKRLSRRASIIGAVIAILALAGTGWLAWHLTHPSPEAGSTAAGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GGPGAPAGRRGPPATTVGVATAERASIPVILEALGTVTPQATVKVRPQVSGVMEKVLFKE
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHC
GQMVKAGDLLATIDPRQFEMALMQASGQRQRDEAQLDSARVTLQRFKTLLEQDSIARQEV
CCEEECCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTQAALVKQLEGTVVIDKASEGTARLNLGYTRVVAPISGRVGLRTVDVGNVVSSSDANGI
HHHHHHHHHCCCCEEEECCCCCCEEEECCEEEEEEECCCCCCEEEEECCCCCCCCCCCCE
ALITQVSPIDVVFSIPQDQVGELQQSASGSAAMKVTAFDRTRSTTLDTGMFASLDNQVDT
EEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCCC
QTGTVKAKARFANSKLALFPSQFVNVQLLVRTIDNAVVVPVTALRHGSTGDYVYVVNTAE
CCCEEEEEEEECCCEEEECCHHHCCCEEEEEHHCCEEEEEEEEECCCCCCCEEEEEECCC
RTVSLRPVQRGQATVDKIVIASGLQPGERVITEGADRLKDGAKVILPGDQPGGGGAGSTG
CEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCCCC
KRQRPGGPASAPAAGASSPAAADAPAADASSPRRRRRASQAEGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MDPRAATPHTGANPPPGKRLSRRASIIGAVIAILALAGTGWLAWHLTHPSPEAGSTAAGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GGPGAPAGRRGPPATTVGVATAERASIPVILEALGTVTPQATVKVRPQVSGVMEKVLFKE
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHC
GQMVKAGDLLATIDPRQFEMALMQASGQRQRDEAQLDSARVTLQRFKTLLEQDSIARQEV
CCEEECCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTQAALVKQLEGTVVIDKASEGTARLNLGYTRVVAPISGRVGLRTVDVGNVVSSSDANGI
HHHHHHHHHCCCCEEEECCCCCCEEEECCEEEEEEECCCCCCEEEEECCCCCCCCCCCCE
ALITQVSPIDVVFSIPQDQVGELQQSASGSAAMKVTAFDRTRSTTLDTGMFASLDNQVDT
EEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCCC
QTGTVKAKARFANSKLALFPSQFVNVQLLVRTIDNAVVVPVTALRHGSTGDYVYVVNTAE
CCCEEEEEEEECCCEEEECCHHHCCCEEEEEHHCCEEEEEEEEECCCCCCCEEEEEECCC
RTVSLRPVQRGQATVDKIVIASGLQPGERVITEGADRLKDGAKVILPGDQPGGGGAGSTG
CEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCCCC
KRQRPGGPASAPAAGASSPAAADAPAADASSPRRRRRASQAEGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA