Click here to switch to the map view.

The map label for this gene is oxc [H]

Identifier: 91788662

GI number: 91788662

Start: 2940989

End: 2942719

Strand: Direct

Name: oxc [H]

Synonym: Bpro_2800

Alternate gene names: 91788662

Gene position: 2940989-2942719 (Clockwise)

Preceding gene: 91788660

Following gene: 91788663

Centisome position: 56.55

GC content: 64.01

Gene sequence:

>1731_bases
ATGACAAACGACACTCAATCACCAGAACTGACCGACGGGTTTCATCTTGTAATCGATGCCCTGAAACTCAACGGGATCGA
CACAATCTTCGGTCTGCCCGGTATTCCCATCACCGATCTGACGCGTATGGCACAGGCCGAAGGCATGCGGGTCATTTCAT
TTCGTCACGAGCAGAACGCCGGCAACGCCGCTGCCATTGCCGGCTTTCTGACGCAAAAGCCGGGCATCTGCCTGACGGTT
TCCGCCCCCGGCTTCCTCAACGGCCTGACCGCGCTGGCCAACGCCACGACGAATTGCTTCCCGATGATCCTGATCAGCGG
CTCCAGCGAACGCGAAATCGTCGACCTGCAGCAGGGCGACTATGAAGAGATGGATCAGCTGGCCATCGCCAAGCCCCTGT
GCAAGGCAGCTTTCCGCGTGCTGAACGCCGAAGACATTGGCGTGGGCATCGCGCGCGCCATTCGCTCCGCTGTCTCTGGC
CGCCCGGGCGGCGTCTATCTGGACCTGCCGGCCAAGCTGTTCGCGCAGACCATGGACGCGCAAGCCGGCAAGGATTCCCT
GATCAAGGTCGTCGATCCGGCCCCGCGCCAGATTCCGGCGCCCGACGCCGTCCAGCGCGCGCTGGACCTGCTCAAGGGCG
CCAAACGCCCGCTCATCCTGCTGGGAAAGGGCGCAGCCTATGCCCAGGCCGATGCCGAGGTCCGTGCCCTGGTCGAGAAG
ACTGGCATCCCCTACCTGCCGATGTCCATGGCCAAGGGCCTCCTGCCCGACACGCATGAACAGTCCGCCGCGGCCGCGCG
CTCCTATGTGCTGCCCGAAGCCGACGTGGTGCTGCTGGTCGGCGCGCGCCTGAACTGGCTGCTCTCGCACGGCAAGGGCA
AGACCTGGGGCGGCAAAGACCACAAGGACTGGGGCCGCCAGAAATTCATCCAGATCGATATCTCCCCCACCGAGGCAGAC
AGCAACGTGGCCATCGACGCCCCGCTGGTCGGCGACATCGGCTCCTGTGTCTCGGCCCTGCTGGCCGGCATCGGTTCGGG
CTGGGCCAAGCCGCCGGCCGATTGGCTGAATGCCATTGCCGAGCGCAAGAACAAGAACATCGCGAAGATGGCCGAGACCC
TGAACAGGAACCCGTCGCCGATGAATTTCCACAGCGCCCTGGCCGTGGTCCGCGACATCTTCAAGGCCCACCCGGAGACC
ATCATGGTGAACGAAGGCGCCAATGCGCTGGACTTCACCCGCAGCATCGTGGACATGTACCAGCCGCGCAAGCGCCTGGA
CGTCGGCACATGGGGCATCATGGGCATCGGCATGGGCTTTGCCGTGGCTGCCGCCGTGGTCACCAAAAAGCCGGTTGTTG
CCATCGAGGGCGACAGCGCCTTCGGCTTCAGCGGCATGGAAGTCGAGACCATCTGCCGCTACAACCTGCCGGTCTGCGTG
GTCATCATGAACAACAATGGCGTGTACCGCGGCACCGATGTCAATACGTCCGGCACCCCCGACGTGGCCCCCACCGTGTT
CGTCAAGAACGCCCGCTACGACAAGCTGATGGAAGCCTTCGGTGGTGTCGGCGTGAACGCCACCACCCCGGGCGAGCTGC
GCCGCGCCATGGACGAAGCGATCAAGTCCGGCAGGCCAACCCTGATCAATGCCGTCATCGACGAGACAGCCGGCACCGAG
AGCGGCCGCATCACCAGCCTGAACCCGCAAAGCGCGGCCAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
GGAGGCGTTGGCTTGGGTCAACGGTTTTTTTCTGGCGCCAACCGATATTGCCAGCCGCTAGCTCAACCTTTATCGAAGTC
AAACGAAGAGACTTTTCATC

Downstream 100 bases:

>100_bases
ATTAGCAAAGCAATCCACTAGGAGTTATGAAGATGTCAAACAAACCACTCAACGGCATAAAAATTATTGACTTCACCCAC
GTCCAGGCCGGTCCCGCGTG

Product: putative oxalyl-CoA decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTNDTQSPELTDGFHLVIDALKLNGIDTIFGLPGIPITDLTRMAQAEGMRVISFRHEQNAGNAAAIAGFLTQKPGICLTV
SAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLNAEDIGVGIARAIRSAVSG
RPGGVYLDLPAKLFAQTMDAQAGKDSLIKVVDPAPRQIPAPDAVQRALDLLKGAKRPLILLGKGAAYAQADAEVRALVEK
TGIPYLPMSMAKGLLPDTHEQSAAAARSYVLPEADVVLLVGARLNWLLSHGKGKTWGGKDHKDWGRQKFIQIDISPTEAD
SNVAIDAPLVGDIGSCVSALLAGIGSGWAKPPADWLNAIAERKNKNIAKMAETLNRNPSPMNFHSALAVVRDIFKAHPET
IMVNEGANALDFTRSIVDMYQPRKRLDVGTWGIMGIGMGFAVAAAVVTKKPVVAIEGDSAFGFSGMEVETICRYNLPVCV
VIMNNNGVYRGTDVNTSGTPDVAPTVFVKNARYDKLMEAFGGVGVNATTPGELRRAMDEAIKSGRPTLINAVIDETAGTE
SGRITSLNPQSAAKKK

Sequences:

>Translated_576_residues
MTNDTQSPELTDGFHLVIDALKLNGIDTIFGLPGIPITDLTRMAQAEGMRVISFRHEQNAGNAAAIAGFLTQKPGICLTV
SAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLNAEDIGVGIARAIRSAVSG
RPGGVYLDLPAKLFAQTMDAQAGKDSLIKVVDPAPRQIPAPDAVQRALDLLKGAKRPLILLGKGAAYAQADAEVRALVEK
TGIPYLPMSMAKGLLPDTHEQSAAAARSYVLPEADVVLLVGARLNWLLSHGKGKTWGGKDHKDWGRQKFIQIDISPTEAD
SNVAIDAPLVGDIGSCVSALLAGIGSGWAKPPADWLNAIAERKNKNIAKMAETLNRNPSPMNFHSALAVVRDIFKAHPET
IMVNEGANALDFTRSIVDMYQPRKRLDVGTWGIMGIGMGFAVAAAVVTKKPVVAIEGDSAFGFSGMEVETICRYNLPVCV
VIMNNNGVYRGTDVNTSGTPDVAPTVFVKNARYDKLMEAFGGVGVNATTPGELRRAMDEAIKSGRPTLINAVIDETAGTE
SGRITSLNPQSAAKKK
>Mature_575_residues
TNDTQSPELTDGFHLVIDALKLNGIDTIFGLPGIPITDLTRMAQAEGMRVISFRHEQNAGNAAAIAGFLTQKPGICLTVS
APGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLNAEDIGVGIARAIRSAVSGR
PGGVYLDLPAKLFAQTMDAQAGKDSLIKVVDPAPRQIPAPDAVQRALDLLKGAKRPLILLGKGAAYAQADAEVRALVEKT
GIPYLPMSMAKGLLPDTHEQSAAAARSYVLPEADVVLLVGARLNWLLSHGKGKTWGGKDHKDWGRQKFIQIDISPTEADS
NVAIDAPLVGDIGSCVSALLAGIGSGWAKPPADWLNAIAERKNKNIAKMAETLNRNPSPMNFHSALAVVRDIFKAHPETI
MVNEGANALDFTRSIVDMYQPRKRLDVGTWGIMGIGMGFAVAAAVVTKKPVVAIEGDSAFGFSGMEVETICRYNLPVCVV
IMNNNGVYRGTDVNTSGTPDVAPTVFVKNARYDKLMEAFGGVGVNATTPGELRRAMDEAIKSGRPTLINAVIDETAGTES
GRITSLNPQSAAKKK

Specific function: Oxalic acid catabolism; second step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Homo sapiens, GI93004078, Length=568, Percent_Identity=38.3802816901408, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI21361361, Length=585, Percent_Identity=28.034188034188, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI1788716, Length=565, Percent_Identity=59.2920353982301, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI87081685, Length=566, Percent_Identity=24.9116607773852, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1790104, Length=560, Percent_Identity=25, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786717, Length=489, Percent_Identity=28.2208588957055, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17531301, Length=556, Percent_Identity=38.4892086330935, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17531299, Length=556, Percent_Identity=38.4892086330935, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17542570, Length=594, Percent_Identity=27.7777777777778, Blast_Score=193, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320816, Length=551, Percent_Identity=34.3012704174229, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6323755, Length=573, Percent_Identity=23.2111692844677, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922626, Length=568, Percent_Identity=38.2042253521127, Blast_Score=380, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017660
- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.8 [H]

Molecular weight: Translated: 61192; Mature: 61061

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDTQSPELTDGFHLVIDALKLNGIDTIFGLPGIPITDLTRMAQAEGMRVISFRHEQNA
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCC
GNAAAIAGFLTQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGD
CCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCC
YEEMDQLAIAKPLCKAAFRVLNAEDIGVGIARAIRSAVSGRPGGVYLDLPAKLFAQTMDA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
QAGKDSLIKVVDPAPRQIPAPDAVQRALDLLKGAKRPLILLGKGAAYAQADAEVRALVEK
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
TGIPYLPMSMAKGLLPDTHEQSAAAARSYVLPEADVVLLVGARLNWLLSHGKGKTWGGKD
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCC
HKDWGRQKFIQIDISPTEADSNVAIDAPLVGDIGSCVSALLAGIGSGWAKPPADWLNAIA
CCCCCCCEEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ERKNKNIAKMAETLNRNPSPMNFHSALAVVRDIFKAHPETIMVNEGANALDFTRSIVDMY
HHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QPRKRLDVGTWGIMGIGMGFAVAAAVVTKKPVVAIEGDSAFGFSGMEVETICRYNLPVCV
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHEECCCCEEE
VIMNNNGVYRGTDVNTSGTPDVAPTVFVKNARYDKLMEAFGGVGVNATTPGELRRAMDEA
EEECCCCEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IKSGRPTLINAVIDETAGTESGRITSLNPQSAAKKK
HHCCCCEEEHHHHHHCCCCCCCEEEECCCHHHCCCC
>Mature Secondary Structure 
TNDTQSPELTDGFHLVIDALKLNGIDTIFGLPGIPITDLTRMAQAEGMRVISFRHEQNA
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCC
GNAAAIAGFLTQKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGD
CCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCC
YEEMDQLAIAKPLCKAAFRVLNAEDIGVGIARAIRSAVSGRPGGVYLDLPAKLFAQTMDA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
QAGKDSLIKVVDPAPRQIPAPDAVQRALDLLKGAKRPLILLGKGAAYAQADAEVRALVEK
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
TGIPYLPMSMAKGLLPDTHEQSAAAARSYVLPEADVVLLVGARLNWLLSHGKGKTWGGKD
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCC
HKDWGRQKFIQIDISPTEADSNVAIDAPLVGDIGSCVSALLAGIGSGWAKPPADWLNAIA
CCCCCCCEEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ERKNKNIAKMAETLNRNPSPMNFHSALAVVRDIFKAHPETIMVNEGANALDFTRSIVDMY
HHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QPRKRLDVGTWGIMGIGMGFAVAAAVVTKKPVVAIEGDSAFGFSGMEVETICRYNLPVCV
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHEECCCCEEE
VIMNNNGVYRGTDVNTSGTPDVAPTVFVKNARYDKLMEAFGGVGVNATTPGELRRAMDEA
EEECCCCEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IKSGRPTLINAVIDETAGTESGRITSLNPQSAAKKK
HHCCCCEEEHHHHHHCCCCCCCEEEECCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157618 [H]