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The map label for this gene is cobL [H]

Identifier: 91788637

GI number: 91788637

Start: 2916532

End: 2917878

Strand: Reverse

Name: cobL [H]

Synonym: Bpro_2775

Alternate gene names: 91788637

Gene position: 2917878-2916532 (Counterclockwise)

Preceding gene: 91788638

Following gene: 91788636

Centisome position: 56.11

GC content: 63.33

Gene sequence:

>1347_bases
TTGAATTCTGAATCAATCGAAACCATGGAAACCATGGAAGCCATGGAAACCAAGGAAGCCATTGAAAAATGCCGCATCCT
CGGCGTGCTGGACGACGGCATCAACAGCCTGAGCCAGAGTGCGCTGGCGCATCTGCAATCTGCTCAGTTGGTGATTGGCG
GCGCACGCACGCTGCAGTTGCTGGCCGTACAGATATCCCCTGATGCGGTGCAGCGCGACCTGACCGGAGCCTTGTCGCAG
GTCCCCGAGTGGATTCGTGCCGCGCAGGCCGCCGGGCAGCGCGTGGTGGTGCTGGCCACGGGCGACCCGCTGTGCCACGG
CATTGCGGCTTACCTGGCCTCGCGGCTGTGCATTGAGGCGATTGAGGTGCTGCCCAATGTCTCTACCTTGCAGCTGGCTT
GTGCCCGCTTGGGGCTGCCGTGGCAGGAAATGAAATTTTCTTCCGTGCACAGCCGTGACGCGGGCGACTGGGTGGCAGGC
GCCGAGCCCGGCCACGGCCTGTATGCGCTGCTGCGCGACATCCGCCAGCACGACCGCCTGGCCGTGCTGACCAGCCCCGA
CAACACGCCCGATCGCATCGCCCGCATGCTGGTGACGGAAGGCCTGGCCGATGACTTTGAAATGGCGGTGGCCGAGCGCC
TTTGCCAGAGCGATGAACGCATCGTCAGCGGAATCAGCATTCATGCCGCCGCGCACATGCCGTTTGCCGATCCCAACGTG
GTGCTGCTGTGGCGCAGCAAATTGCGTGCGCCGCAGGTGTTGTTTGGCCTGCCCGATGTCAGCTTTGAGCAGCGTCACCC
GGATAAGGGCTTGATCACCAAAAACGAGGTGCGCGCCGTCTCGCTGGCGCGCATGCAGTTGCGTGCCGACAGCGTGGTGT
GGGACATCGGTGCAGGCTCCGGTTCGGTCGGCCTGGAGGCGGCGCGGCTGTGCCGCCAGGGCCATGTCTATGCCATCGAA
AAAAATGTGGACGACAGCGCCATCGTGGGCCGTAACCGTCAGGCCATGGGCATCAGCAACCATACCCTGGTGCACGGCAA
AGCCCCCGAGGGCCTGGCGGCCTGGGCTGACCCGGACGCGGTGTTTATCGGTGGCTCAGGCGGTGAACTGGCCGAGCTGA
TTGCGCTGATCCTGAAACGCCTGAAACCGGGTGGCTGGCTGGTGATGAATTTTGTGACCATTGAAAACCTGGGCACGGCG
GTCGAAACGCTCAAAAGCCTGGGCGCCGGCTGGGACGTACTGCAGCTCCAGGCCTCGCGCAGCAAACCTATTTTGCACAT
GAACCGCATGGCGGCCGAGAACCCGGTGTGGATCGTCTGCGCCCAGCCGGGAGTTGAGCATGGTTAA

Upstream 100 bases:

>100_bases
CGCAGCGGGTCATACAGACCCTGCGCACGCGTTACCCCGATCAATTTGAACTGAAAGTGCTGGTCTGCGACTTTGACGGT
CGCAAGATTGCGGAGGCCTC

Downstream 100 bases:

>100_bases
GCCCGGTCAACTCTACGGCGTATCGCTGGGCCCCGGTGACCCGGGCCTGATCACCCGCCGCGCCTGGGCCTTGCTTGAGC
GCGCCGATGCCGTCTGGACC

Product: precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNSESIETMETMEAMETKEAIEKCRILGVLDDGINSLSQSALAHLQSAQLVIGGARTLQLLAVQISPDAVQRDLTGALSQ
VPEWIRAAQAAGQRVVVLATGDPLCHGIAAYLASRLCIEAIEVLPNVSTLQLACARLGLPWQEMKFSSVHSRDAGDWVAG
AEPGHGLYALLRDIRQHDRLAVLTSPDNTPDRIARMLVTEGLADDFEMAVAERLCQSDERIVSGISIHAAAHMPFADPNV
VLLWRSKLRAPQVLFGLPDVSFEQRHPDKGLITKNEVRAVSLARMQLRADSVVWDIGAGSGSVGLEAARLCRQGHVYAIE
KNVDDSAIVGRNRQAMGISNHTLVHGKAPEGLAAWADPDAVFIGGSGGELAELIALILKRLKPGGWLVMNFVTIENLGTA
VETLKSLGAGWDVLQLQASRSKPILHMNRMAAENPVWIVCAQPGVEHG

Sequences:

>Translated_448_residues
MNSESIETMETMEAMETKEAIEKCRILGVLDDGINSLSQSALAHLQSAQLVIGGARTLQLLAVQISPDAVQRDLTGALSQ
VPEWIRAAQAAGQRVVVLATGDPLCHGIAAYLASRLCIEAIEVLPNVSTLQLACARLGLPWQEMKFSSVHSRDAGDWVAG
AEPGHGLYALLRDIRQHDRLAVLTSPDNTPDRIARMLVTEGLADDFEMAVAERLCQSDERIVSGISIHAAAHMPFADPNV
VLLWRSKLRAPQVLFGLPDVSFEQRHPDKGLITKNEVRAVSLARMQLRADSVVWDIGAGSGSVGLEAARLCRQGHVYAIE
KNVDDSAIVGRNRQAMGISNHTLVHGKAPEGLAAWADPDAVFIGGSGGELAELIALILKRLKPGGWLVMNFVTIENLGTA
VETLKSLGAGWDVLQLQASRSKPILHMNRMAAENPVWIVCAQPGVEHG
>Mature_448_residues
MNSESIETMETMEAMETKEAIEKCRILGVLDDGINSLSQSALAHLQSAQLVIGGARTLQLLAVQISPDAVQRDLTGALSQ
VPEWIRAAQAAGQRVVVLATGDPLCHGIAAYLASRLCIEAIEVLPNVSTLQLACARLGLPWQEMKFSSVHSRDAGDWVAG
AEPGHGLYALLRDIRQHDRLAVLTSPDNTPDRIARMLVTEGLADDFEMAVAERLCQSDERIVSGISIHAAAHMPFADPNV
VLLWRSKLRAPQVLFGLPDVSFEQRHPDKGLITKNEVRAVSLARMQLRADSVVWDIGAGSGSVGLEAARLCRQGHVYAIE
KNVDDSAIVGRNRQAMGISNHTLVHGKAPEGLAAWADPDAVFIGGSGGELAELIALILKRLKPGGWLVMNFVTIENLGTA
VETLKSLGAGWDVLQLQASRSKPILHMNRMAAENPVWIVCAQPGVEHG

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 48231; Mature: 48231

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSESIETMETMEAMETKEAIEKCRILGVLDDGINSLSQSALAHLQSAQLVIGGARTLQL
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCEEEECCCEEEE
LAVQISPDAVQRDLTGALSQVPEWIRAAQAAGQRVVVLATGDPLCHGIAAYLASRLCIEA
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
IEVLPNVSTLQLACARLGLPWQEMKFSSVHSRDAGDWVAGAEPGHGLYALLRDIRQHDRL
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
AVLTSPDNTPDRIARMLVTEGLADDFEMAVAERLCQSDERIVSGISIHAAAHMPFADPNV
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCEEEEEEEECCCCCCCE
VLLWRSKLRAPQVLFGLPDVSFEQRHPDKGLITKNEVRAVSLARMQLRADSVVWDIGAGS
EEEECCCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCC
GSVGLEAARLCRQGHVYAIEKNVDDSAIVGRNRQAMGISNHTLVHGKAPEGLAAWADPDA
CCCHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCEECCCCCEEEECCCCCCCEECCCCCE
VFIGGSGGELAELIALILKRLKPGGWLVMNFVTIENLGTAVETLKSLGAGWDVLQLQASR
EEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEECCC
SKPILHMNRMAAENPVWIVCAQPGVEHG
CCCEEEHHHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MNSESIETMETMEAMETKEAIEKCRILGVLDDGINSLSQSALAHLQSAQLVIGGARTLQL
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCEEEECCCEEEE
LAVQISPDAVQRDLTGALSQVPEWIRAAQAAGQRVVVLATGDPLCHGIAAYLASRLCIEA
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
IEVLPNVSTLQLACARLGLPWQEMKFSSVHSRDAGDWVAGAEPGHGLYALLRDIRQHDRL
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
AVLTSPDNTPDRIARMLVTEGLADDFEMAVAERLCQSDERIVSGISIHAAAHMPFADPNV
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCEEEEEEEECCCCCCCE
VLLWRSKLRAPQVLFGLPDVSFEQRHPDKGLITKNEVRAVSLARMQLRADSVVWDIGAGS
EEEECCCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCC
GSVGLEAARLCRQGHVYAIEKNVDDSAIVGRNRQAMGISNHTLVHGKAPEGLAAWADPDA
CCCHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCEECCCCCEEEECCCCCCCEECCCCCE
VFIGGSGGELAELIALILKRLKPGGWLVMNFVTIENLGTAVETLKSLGAGWDVLQLQASR
EEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEECCC
SKPILHMNRMAAENPVWIVCAQPGVEHG
CCCEEEHHHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]