Click here to switch to the map view.

The map label for this gene is hmuU [H]

Identifier: 91788632

GI number: 91788632

Start: 2912114

End: 2913100

Strand: Reverse

Name: hmuU [H]

Synonym: Bpro_2770

Alternate gene names: 91788632

Gene position: 2913100-2912114 (Counterclockwise)

Preceding gene: 91788633

Following gene: 91788631

Centisome position: 56.02

GC content: 62.82

Gene sequence:

>987_bases
GTGCTTTGGGGCGTGCTGCTGGTCTTGTGTGTGGTGTCGGTGAAAGCCGGCGCCGTGCCTGTGAGCCTGGAACGATTGGT
GCAGAGTCTGTCGCTCCTGGTGTCCGGTGCACCACAAGCGCTTTACGGAATGGAGGACCGCATCGTCGTAGAGCTGCGCC
TGCCCAGAGTCATTCTTGCGATGCTGGTCGGCGCAGGACTGGCTGTGGTGGGAACGCTGTTGCAGACGGTAACCCGCAAC
GAGTTGTCGGACCCCTATCTGTTCGGTCTGTCTTCCGGTTCTGCCGCAGGAGCCGTTGCAGCAATTACCTTCACCGGGGA
GGCATTCGGTCTGTGGTCGCTACCGCTGGCGGCACTGGCCGGCGGCCTGGCATCGGTGGCTGCTGTGCTGCTGCTGTTGC
GCGGGTACGCAAACCACTCCTCCGACCAGTTGATTCTGGCGGGGCTTTCGGTTTCATTTTTGTTCACCGCCTTGACCTAC
TACCTCACGTTTCTGGGCGACCAGCGAGCGGCACAGTCAGTGCTGTTCTGGACCATGGGAGGGCTGGGCGGCGCGCGCTG
GGACAACCTGTTCTTGCCCTTGCTCGGTGTGGTCACCGTGGGAGGGTTTGCCATTTTCAAAACGCGCGCGCTGGATGCCA
TGCTGGCCGGCGATCACACTGCGCATAGCCTGGGTGTGGAGCCCGAGCGCCTGCGCGCGCAAACCTTCGTGGTATGCGCC
CTGGCTACCGCGTGCTTTGTGTCGGTATCCGGTGTCATCGGATTTGTGGGCCTGATGGTGCCGCACCTGGCACGCGCCCG
GGTCGGCGCGTTGCATCAAAGACTACTCGGCATGGGCATGCTCACCGGAGCCGTGCTGCTGCTGGGCAGTGACCTCGTTA
GCCGTACCGTACTGGCGCCACAGGAGTTGCCGGTAGGCATTGTGACGGCGAGTTTGGGGGCGCTGTTTGTCATGCGCATC
GTGATGCGCAAGCCGGAGGAGGTATGA

Upstream 100 bases:

>100_bases
AGTTAACCCCTGGGCCCGCCAACATCACTGCCATCGAGAAAATGGCAAAGGCGCTCAAGCTTTGATCACTTTGCCCCGCT
CCTTCGGGTTGACAGCTGCG

Downstream 100 bases:

>100_bases
CAAACAAAGACGCCATACCCCTGCCGTACGCCATCGCTTTGGGTCTGGGGTGTGACCGCGGTACCCCGGCGGATGTGATT
GCCTTTGCCGTGGACACGGC

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLWGVLLVLCVVSVKAGAVPVSLERLVQSLSLLVSGAPQALYGMEDRIVVELRLPRVILAMLVGAGLAVVGTLLQTVTRN
ELSDPYLFGLSSGSAAGAVAAITFTGEAFGLWSLPLAALAGGLASVAAVLLLLRGYANHSSDQLILAGLSVSFLFTALTY
YLTFLGDQRAAQSVLFWTMGGLGGARWDNLFLPLLGVVTVGGFAIFKTRALDAMLAGDHTAHSLGVEPERLRAQTFVVCA
LATACFVSVSGVIGFVGLMVPHLARARVGALHQRLLGMGMLTGAVLLLGSDLVSRTVLAPQELPVGIVTASLGALFVMRI
VMRKPEEV

Sequences:

>Translated_328_residues
MLWGVLLVLCVVSVKAGAVPVSLERLVQSLSLLVSGAPQALYGMEDRIVVELRLPRVILAMLVGAGLAVVGTLLQTVTRN
ELSDPYLFGLSSGSAAGAVAAITFTGEAFGLWSLPLAALAGGLASVAAVLLLLRGYANHSSDQLILAGLSVSFLFTALTY
YLTFLGDQRAAQSVLFWTMGGLGGARWDNLFLPLLGVVTVGGFAIFKTRALDAMLAGDHTAHSLGVEPERLRAQTFVVCA
LATACFVSVSGVIGFVGLMVPHLARARVGALHQRLLGMGMLTGAVLLLGSDLVSRTVLAPQELPVGIVTASLGALFVMRI
VMRKPEEV
>Mature_328_residues
MLWGVLLVLCVVSVKAGAVPVSLERLVQSLSLLVSGAPQALYGMEDRIVVELRLPRVILAMLVGAGLAVVGTLLQTVTRN
ELSDPYLFGLSSGSAAGAVAAITFTGEAFGLWSLPLAALAGGLASVAAVLLLLRGYANHSSDQLILAGLSVSFLFTALTY
YLTFLGDQRAAQSVLFWTMGGLGGARWDNLFLPLLGVVTVGGFAIFKTRALDAMLAGDHTAHSLGVEPERLRAQTFVVCA
LATACFVSVSGVIGFVGLMVPHLARARVGALHQRLLGMGMLTGAVLLLGSDLVSRTVLAPQELPVGIVTASLGALFVMRI
VMRKPEEV

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=283, Percent_Identity=36.3957597173145, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=35.0180505415162, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788004, Length=270, Percent_Identity=33.7037037037037, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786804, Length=325, Percent_Identity=30.4615384615385, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=30.4964539007092, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786805, Length=281, Percent_Identity=33.4519572953737, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34237; Mature: 34237

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWGVLLVLCVVSVKAGAVPVSLERLVQSLSLLVSGAPQALYGMEDRIVVELRLPRVILA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHH
MLVGAGLAVVGTLLQTVTRNELSDPYLFGLSSGSAAGAVAAITFTGEAFGLWSLPLAALA
HHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHH
GGLASVAAVLLLLRGYANHSSDQLILAGLSVSFLFTALTYYLTFLGDQRAAQSVLFWTMG
CHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GLGGARWDNLFLPLLGVVTVGGFAIFKTRALDAMLAGDHTAHSLGVEPERLRAQTFVVCA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHH
LATACFVSVSGVIGFVGLMVPHLARARVGALHQRLLGMGMLTGAVLLLGSDLVSRTVLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QELPVGIVTASLGALFVMRIVMRKPEEV
CCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLWGVLLVLCVVSVKAGAVPVSLERLVQSLSLLVSGAPQALYGMEDRIVVELRLPRVILA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHH
MLVGAGLAVVGTLLQTVTRNELSDPYLFGLSSGSAAGAVAAITFTGEAFGLWSLPLAALA
HHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHH
GGLASVAAVLLLLRGYANHSSDQLILAGLSVSFLFTALTYYLTFLGDQRAAQSVLFWTMG
CHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GLGGARWDNLFLPLLGVVTVGGFAIFKTRALDAMLAGDHTAHSLGVEPERLRAQTFVVCA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHH
LATACFVSVSGVIGFVGLMVPHLARARVGALHQRLLGMGMLTGAVLLLGSDLVSRTVLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QELPVGIVTASLGALFVMRIVMRKPEEV
CCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]