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The map label for this gene is crt [H]

Identifier: 91788612

GI number: 91788612

Start: 2890626

End: 2891405

Strand: Reverse

Name: crt [H]

Synonym: Bpro_2750

Alternate gene names: 91788612

Gene position: 2891405-2890626 (Counterclockwise)

Preceding gene: 91788613

Following gene: 91788611

Centisome position: 55.6

GC content: 64.62

Gene sequence:

>780_bases
ATGAGTGACGGAGCAGTACACCTGACGGTCAATGCCGGCGTGGCGTCGGTGGTGTTCGACCGTCCGCAGGCGCGCAATGC
CATGACCTGGGCCATGTACAGGCAACTGGGCCGCATTTGCGAAGCGCTGCAAACGGATCGCTCGGTCCGTGTCGTGACCT
TCGAGGGCGCTGGCGGTGAGGCCTTTGTGGCCGGCACCGACATCGAGCAGTTCCAGGCTTTCGAGAGTGGTGAAGACGGT
GTGGCTTATGAACGCACCATTGACCGCGGCATTGGCCTGATCGAATCACTGCCGATGCCGACCGTGGCGGTGATTAGCGG
CTGGACCATCGGTGGTGGCCTGGCGATTGCCACCGCCTGCGATTTCCGCATTGCAACGCCGGCCTCCCGCTTTGGCGTGC
CGATCGCCAAAACCCTGGGCAATTGCCTGTCGATGGCCAACCTGGCGCGACTCAGTGCCGTGTGGGGCGCGCAGCGCGTC
AAGCGCATGCTGCTGCTCGCCGAACTGCTCAATGCCGACGAAGCCCTGGCCTGCGGCTTTCTCGGCCAGATGTGCGAGCC
TGCTGAGCTGGGCGCCGCGGCCGCCCGTCTGTGCGAGCGCCTCGCGTCGCTGGCGCCCGTCACACAGAGCGTGACCAAGG
AAGCCCTGCGGCGTTTGCTGGTGCAGGGCTTGCCCGACGGTGACGACCTGATACGCCGGTGCTACGGCAGCAGAGACTTT
CATGAAGGCGTAGAGGCGTTTGTCGCCAAAAGAAGCCCGGTGTGGACAGGTGTGGTTTGA

Upstream 100 bases:

>100_bases
ATCCGCCGCTGCTGGGTGAACACACGCAGGACGTCCTGGACGAGTTGGGCCTGAGTGATGCCGAATGTGCCGAGCTGCAG
GCACAGGGGGCATTTGCAGC

Downstream 100 bases:

>100_bases
AAGCTGCACACGCCATTTCGGCTTGACCTGACCCGCTTCGCCGATTCACGCCGTTCGCCCCGGCCTCGGGCGGGTGTTGG
TGCCAAATGCACAAAAAATG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSDGAVHLTVNAGVASVVFDRPQARNAMTWAMYRQLGRICEALQTDRSVRVVTFEGAGGEAFVAGTDIEQFQAFESGEDG
VAYERTIDRGIGLIESLPMPTVAVISGWTIGGGLAIATACDFRIATPASRFGVPIAKTLGNCLSMANLARLSAVWGAQRV
KRMLLLAELLNADEALACGFLGQMCEPAELGAAAARLCERLASLAPVTQSVTKEALRRLLVQGLPDGDDLIRRCYGSRDF
HEGVEAFVAKRSPVWTGVV

Sequences:

>Translated_259_residues
MSDGAVHLTVNAGVASVVFDRPQARNAMTWAMYRQLGRICEALQTDRSVRVVTFEGAGGEAFVAGTDIEQFQAFESGEDG
VAYERTIDRGIGLIESLPMPTVAVISGWTIGGGLAIATACDFRIATPASRFGVPIAKTLGNCLSMANLARLSAVWGAQRV
KRMLLLAELLNADEALACGFLGQMCEPAELGAAAARLCERLASLAPVTQSVTKEALRRLLVQGLPDGDDLIRRCYGSRDF
HEGVEAFVAKRSPVWTGVV
>Mature_258_residues
SDGAVHLTVNAGVASVVFDRPQARNAMTWAMYRQLGRICEALQTDRSVRVVTFEGAGGEAFVAGTDIEQFQAFESGEDGV
AYERTIDRGIGLIESLPMPTVAVISGWTIGGGLAIATACDFRIATPASRFGVPIAKTLGNCLSMANLARLSAVWGAQRVK
RMLLLAELLNADEALACGFLGQMCEPAELGAAAARLCERLASLAPVTQSVTKEALRRLLVQGLPDGDDLIRRCYGSRDFH
EGVEAFVAKRSPVWTGVV

Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=27.0916334661355, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=25.609756097561, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI70995211, Length=215, Percent_Identity=31.1627906976744, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI157694516, Length=179, Percent_Identity=26.2569832402235, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI213417737, Length=179, Percent_Identity=26.2569832402235, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI157694520, Length=128, Percent_Identity=28.90625, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI20127408, Length=185, Percent_Identity=24.8648648648649, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=29.6992481203008, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082183, Length=264, Percent_Identity=26.1363636363636, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787659, Length=248, Percent_Identity=29.4354838709677, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788597, Length=253, Percent_Identity=25.296442687747, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787660, Length=255, Percent_Identity=29.0196078431373, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=27.2251308900524, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=26.2096774193548, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=258, Percent_Identity=25.5813953488372, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=24.8847926267281, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=22.4576271186441, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=238, Percent_Identity=26.890756302521, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=27.1653543307087, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI20129971, Length=255, Percent_Identity=25.8823529411765, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=255, Percent_Identity=25.8823529411765, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920382, Length=260, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583077, Length=192, Percent_Identity=27.6041666666667, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583079, Length=192, Percent_Identity=27.6041666666667, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27604; Mature: 27473

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGAVHLTVNAGVASVVFDRPQARNAMTWAMYRQLGRICEALQTDRSVRVVTFEGAGGE
CCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
AFVAGTDIEQFQAFESGEDGVAYERTIDRGIGLIESLPMPTVAVISGWTIGGGLAIATAC
EEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHC
DFRIATPASRFGVPIAKTLGNCLSMANLARLSAVWGAQRVKRMLLLAELLNADEALACGF
CEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGQMCEPAELGAAAARLCERLASLAPVTQSVTKEALRRLLVQGLPDGDDLIRRCYGSRDF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
HEGVEAFVAKRSPVWTGVV
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDGAVHLTVNAGVASVVFDRPQARNAMTWAMYRQLGRICEALQTDRSVRVVTFEGAGGE
CCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
AFVAGTDIEQFQAFESGEDGVAYERTIDRGIGLIESLPMPTVAVISGWTIGGGLAIATAC
EEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHC
DFRIATPASRFGVPIAKTLGNCLSMANLARLSAVWGAQRVKRMLLLAELLNADEALACGF
CEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGQMCEPAELGAAAARLCERLASLAPVTQSVTKEALRRLLVQGLPDGDDLIRRCYGSRDF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
HEGVEAFVAKRSPVWTGVV
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]