BacMap

Definition	Polaromonas sp. JS666 chromosome, complete genome.
Accession	NC_007948
Length	5,200,264

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The map label for this gene is hbdH1 [H]

Identifier: 91788567

GI number: 91788567

Start: 2850896

End: 2851678

Strand: Direct

Name: hbdH1 [H]

Synonym: Bpro_2705

Alternate gene names: 91788567

Gene position: 2850896-2851678 (Clockwise)

Preceding gene: 91788560

Following gene: 91788571

Centisome position: 54.82

GC content: 61.69

Gene sequence:

>783_bases
ATGCTCAAAGGTAAAACAGCTCTCGTTACCGGCTCCACCAGCGGCATCGGCCTGGGCATTGCCAAATCCCTCGCCGCACA
GGGCGCCAACATCGTCCTCAATGGGTTTGGCGATGTGGACGGGCCCAAGGCGGAGATCCTGGCGCTCGGCGTCAAGGTGG
CCTACCACGGTGCCGACATGAGCAAGCCCGCAGACATTGAAGACATGATGAAATTCGCCGCCTCGCAGTTCGGGCAGGTC
GACATTCTCGTCAACAACGCGGGCATCCAGCATGTGGCCCGGGTAGAAAACTTCCCGGTTGAAAAATGGGATGCGGTCAT
CGCGATCAACCTGACCAGCGCCTTTCATGCCACACGCCTGGCGCTGCCCGCCATGCTGGCCGCGGACAATGGCAAGGGCT
GGGGCCGCATCATCAATATCGCCTCGGTGCATGGCCTCGTCGGCTCCGCGGAAAAATCAGCCTATGTGGCGGCCAAGCAC
GGCATTGTCGGACTGACCAAGGTCACCGCGCTTGAGAACGCCACCAGCGGCGTGACCTGCAACGCCATCTGCCCCGGTTG
GGTGCTGACACCCCTGGTACAAAAACAGGTGGATGCCAGGGCTGCGGCGGGAAATATTTCCATCGAGGCAGCCACCCAGC
AGCTGCTGGGTGAAAAAGAACCTTCGATGCGATTCACCACGCCCGAAGAACTGGGCGCGCTGGCGGTGTTCTTCTGCTCT
GCGGCGGGCAACAATGTACGCGGCGTCGCGTGGAACATGGACGGCGGCTGGACGGCGCAGTAA

Upstream 100 bases:

>100_bases
TTGAAAGGCTCGATAATTGCTTGAGAAATTTTTTGGCCCCCTGCCTGCAGGCGCCGTTTAGATCTCATGTCGACCATCGT
AAATCATCCGGAGAAACACC

Downstream 100 bases:

>100_bases
TCTGAAGCCCGAAGCGCTCAGCCACAAACGCTCTTTCCACTGCGCCCACGGCGCCGGTACAGCAATCTCCAATCTCTACA
GCAACCGGCTGACGTAGCTG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLKGKTALVTGSTSGIGLGIAKSLAAQGANIVLNGFGDVDGPKAEILALGVKVAYHGADMSKPADIEDMMKFAASQFGQV
DILVNNAGIQHVARVENFPVEKWDAVIAINLTSAFHATRLALPAMLAADNGKGWGRIINIASVHGLVGSAEKSAYVAAKH
GIVGLTKVTALENATSGVTCNAICPGWVLTPLVQKQVDARAAAGNISIEAATQQLLGEKEPSMRFTTPEELGALAVFFCS
AAGNNVRGVAWNMDGGWTAQ

Sequences:

>Translated_260_residues
MLKGKTALVTGSTSGIGLGIAKSLAAQGANIVLNGFGDVDGPKAEILALGVKVAYHGADMSKPADIEDMMKFAASQFGQV
DILVNNAGIQHVARVENFPVEKWDAVIAINLTSAFHATRLALPAMLAADNGKGWGRIINIASVHGLVGSAEKSAYVAAKH
GIVGLTKVTALENATSGVTCNAICPGWVLTPLVQKQVDARAAAGNISIEAATQQLLGEKEPSMRFTTPEELGALAVFFCS
AAGNNVRGVAWNMDGGWTAQ
>Mature_260_residues
MLKGKTALVTGSTSGIGLGIAKSLAAQGANIVLNGFGDVDGPKAEILALGVKVAYHGADMSKPADIEDMMKFAASQFGQV
DILVNNAGIQHVARVENFPVEKWDAVIAINLTSAFHATRLALPAMLAADNGKGWGRIINIASVHGLVGSAEKSAYVAAKH
GIVGLTKVTALENATSGVTCNAICPGWVLTPLVQKQVDARAAAGNISIEAATQQLLGEKEPSMRFTTPEELGALAVFFCS
AAGNNVRGVAWNMDGGWTAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=36, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=31.0077519379845, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=35, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI15277342, Length=272, Percent_Identity=28.6764705882353, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=28.5171102661597, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.1317829457364, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=32.6829268292683, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=31.7948717948718, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI83715985, Length=185, Percent_Identity=34.5945945945946, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=34.4827586206897, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=28.2868525896414, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=240, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=28.5, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI109715829, Length=204, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=35.1351351351351, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=33.976833976834, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=34.2412451361868, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=32.03125, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=29.6153846153846, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=31.1538461538462, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.4615384615385, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=26.2548262548263, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=264, Percent_Identity=30.3030303030303, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=30.5660377358491, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=29.9242424242424, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=32.8205128205128, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=34.020618556701, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=34.375, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=28.0898876404494, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=32.3886639676113, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=198, Percent_Identity=30.8080808080808, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=30.1020408163265, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=31.5, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=29.4416243654822, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=205, Percent_Identity=31.219512195122, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=208, Percent_Identity=27.8846153846154, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=197, Percent_Identity=27.9187817258883, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=28.643216080402, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=31.3725490196078, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=27.3076923076923, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=28.2178217821782, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=24.9084249084249, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=25.5905511811024, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=31.6279069767442, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320089, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=30.1526717557252, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357041, Length=264, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=29.5454545454545, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=33.0049261083744, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=34.2105263157895, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28571526, Length=264, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=27.7992277992278, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=28.9340101522843, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17647419, Length=224, Percent_Identity=26.7857142857143, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665264, Length=144, Percent_Identity=37.5, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=31.3131313131313, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=31.3131313131313, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=31.8181818181818, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571387, Length=209, Percent_Identity=25.3588516746411, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584744, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=31.7647058823529, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=30.9941520467836, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=28.8557213930348, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26851; Mature: 26851

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGKTALVTGSTSGIGLGIAKSLAAQGANIVLNGFGDVDGPKAEILALGVKVAYHGADM
CCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCC
SKPADIEDMMKFAASQFGQVDILVNNAGIQHVARVENFPVEKWDAVIAINLTSAFHATRL
CCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHH
ALPAMLAADNGKGWGRIINIASVHGLVGSAEKSAYVAAKHGIVGLTKVTALENATSGVTC
HHHHEEECCCCCCCEEEEEEEHHHHHHCCCCCCEEEEECCCCEEEEHHHHHCCCCCCEEE
NAICPGWVLTPLVQKQVDARAAAGNISIEAATQQLLGEKEPSMRFTTPEELGALAVFFCS
ECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCEECCHHHHHHEEEEEEC
AAGNNVRGVAWNMDGGWTAQ
CCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MLKGKTALVTGSTSGIGLGIAKSLAAQGANIVLNGFGDVDGPKAEILALGVKVAYHGADM
CCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCC
SKPADIEDMMKFAASQFGQVDILVNNAGIQHVARVENFPVEKWDAVIAINLTSAFHATRL
CCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHH
ALPAMLAADNGKGWGRIINIASVHGLVGSAEKSAYVAAKHGIVGLTKVTALENATSGVTC
HHHHEEECCCCCCCEEEEEEEHHHHHHCCCCCCEEEEECCCCEEEEHHHHHCCCCCCEEE
NAICPGWVLTPLVQKQVDARAAAGNISIEAATQQLLGEKEPSMRFTTPEELGALAVFFCS
ECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCEECCHHHHHHEEEEEEC
AAGNNVRGVAWNMDGGWTAQ
CCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA