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The map label for this gene is hipA [C]

Identifier: 91788511

GI number: 91788511

Start: 2788044

End: 2789387

Strand: Reverse

Name: hipA [C]

Synonym: Bpro_2649

Alternate gene names: 91788511

Gene position: 2789387-2788044 (Counterclockwise)

Preceding gene: 91788512

Following gene: 91788510

Centisome position: 53.64

GC content: 66.89

Gene sequence:

>1344_bases
ATGAACGTCCTGGCGCTCGATATCTACGTGGGCTCCCTGCGGGCCGGGCTGCTGTTCCAGTACGGCACGGGCAGCACCGC
GCTCACGCGCTTCATTCCAGACCCCTCCTTCTGGTCGCGGCCCGACGCGCCGGTGCTGTCGTGGGCCGCCACCGATGACG
ACCCCCAGCGCCGTGAAATTTTCTGGCGCAGCTACGTCAGCACGCCTTTTTTCAATGCGGAAGGTGGCCGCCTGCCGGCT
TTTTTCCAGAACCTGCTGCCCGAGGGGCCGCTGCGCCGCCACCTCGAAGAGCTGCGCGGCTGCGGGCCGGGCGACCACTT
CGACCTGCTGGCCGCCTGCGGCACCGACTTGCCGGGCAATGTCTACGCTTACCCCGCCCACCTCGATGCCGACGCGCTCG
CTGCCGTGGTGACCCAGCACAACGACGCGCTGGAGATGTCCGTCACGGCCGACCCCTTGCCCGAGGCCACGTCCCTGTCG
GGCGTGCAACCCAAGCTTGCACTGGTCGCGCAGCATGGGCGTTATGTGGCGCGGACCCGGGACGTGCAGGGCACGCACAT
CATTGCCAAGCTGCCGACGGTTGAATATGCCTTGCTGCCCGAGGTGGAAGAGTTGTCGCTGCGGCTTGCGCAGGCCGCCG
GCGCAGATGTCTGCGCCGCATGGCTGGCCCCGCTGGAGCAGATCGTGGCCGAGCAGCCCTTTGTGCTGGGCGAGAGCCGG
CATTTTCTGGTGGTCAGGCGCTTTGACCGCGGGCCCGGGGGGCACATCCACTGCGAAGACTTCGCGCAGATCCTGCGCAT
ACAGCCCGAAGAAAAATATACGCACCCGGCTGCCACCTACGCCACCATGGCCAGCACGCTGCGCGGCGGCATGGGTCTGG
GACAGCGGGGCGAGGCCGCTGCCGAAGAACTGATCCGCCGTGCGATGGTCAACGAGATGCTGGGCAACTACGACGCGCAT
GTGAAGAATTTCGGGGTGCTCTACCGCGATGGCCGCACACCGGAATTGTCTCCAGCCTACGACGTGGTGGCCTACGCCGC
CTACCTGGGGGGACGCGGCCATGCCTTGCGCTTTGTGCCCGGTGGCGAAAAACAGGCGCGGCTCACCCCGCAGACCGTGC
GCAGCTTTTGCAACGCCACCGGCATGTTCGAGACCCGCGTGCGCGGCGTGCTCAATGACGCAGTGGGCAAAGCCTGCGCC
TCCTGGCCGTCATTGATTGAAGCCAGCAGCCTGCTGGACAAGCAAAAGCACAACCTGCTGCGGCATTTTGAAGCGTGCGA
CGCGGTGCAGAGCTGGCGGCGCAGGCGCGCAGGCAGTGCCGGCCGCAAGGCTGTGGCACCCTGA

Upstream 100 bases:

>100_bases
GTACTGGAGAGGGCCCTGAGCCGGCGCTTTCCCAGGTTGACCGAATCATTGCGCAAACCCGATTGCGCTCCCAGGCCGGC
GCCAAAGGCCCGCTGCCCAA

Downstream 100 bases:

>100_bases
AGCTTGCACGGTGCTTGCTAGACAATCTCAAACCCTTGAAATCTGGAGCCCCCCAATGATTTTTGCGCCCGACCTTGCGA
CGGTTACCCACGGCATCCAA

Product: HipA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNVLALDIYVGSLRAGLLFQYGTGSTALTRFIPDPSFWSRPDAPVLSWAATDDDPQRREIFWRSYVSTPFFNAEGGRLPA
FFQNLLPEGPLRRHLEELRGCGPGDHFDLLAACGTDLPGNVYAYPAHLDADALAAVVTQHNDALEMSVTADPLPEATSLS
GVQPKLALVAQHGRYVARTRDVQGTHIIAKLPTVEYALLPEVEELSLRLAQAAGADVCAAWLAPLEQIVAEQPFVLGESR
HFLVVRRFDRGPGGHIHCEDFAQILRIQPEEKYTHPAATYATMASTLRGGMGLGQRGEAAAEELIRRAMVNEMLGNYDAH
VKNFGVLYRDGRTPELSPAYDVVAYAAYLGGRGHALRFVPGGEKQARLTPQTVRSFCNATGMFETRVRGVLNDAVGKACA
SWPSLIEASSLLDKQKHNLLRHFEACDAVQSWRRRRAGSAGRKAVAP

Sequences:

>Translated_447_residues
MNVLALDIYVGSLRAGLLFQYGTGSTALTRFIPDPSFWSRPDAPVLSWAATDDDPQRREIFWRSYVSTPFFNAEGGRLPA
FFQNLLPEGPLRRHLEELRGCGPGDHFDLLAACGTDLPGNVYAYPAHLDADALAAVVTQHNDALEMSVTADPLPEATSLS
GVQPKLALVAQHGRYVARTRDVQGTHIIAKLPTVEYALLPEVEELSLRLAQAAGADVCAAWLAPLEQIVAEQPFVLGESR
HFLVVRRFDRGPGGHIHCEDFAQILRIQPEEKYTHPAATYATMASTLRGGMGLGQRGEAAAEELIRRAMVNEMLGNYDAH
VKNFGVLYRDGRTPELSPAYDVVAYAAYLGGRGHALRFVPGGEKQARLTPQTVRSFCNATGMFETRVRGVLNDAVGKACA
SWPSLIEASSLLDKQKHNLLRHFEACDAVQSWRRRRAGSAGRKAVAP
>Mature_447_residues
MNVLALDIYVGSLRAGLLFQYGTGSTALTRFIPDPSFWSRPDAPVLSWAATDDDPQRREIFWRSYVSTPFFNAEGGRLPA
FFQNLLPEGPLRRHLEELRGCGPGDHFDLLAACGTDLPGNVYAYPAHLDADALAAVVTQHNDALEMSVTADPLPEATSLS
GVQPKLALVAQHGRYVARTRDVQGTHIIAKLPTVEYALLPEVEELSLRLAQAAGADVCAAWLAPLEQIVAEQPFVLGESR
HFLVVRRFDRGPGGHIHCEDFAQILRIQPEEKYTHPAATYATMASTLRGGMGLGQRGEAAAEELIRRAMVNEMLGNYDAH
VKNFGVLYRDGRTPELSPAYDVVAYAAYLGGRGHALRFVPGGEKQARLTPQTVRSFCNATGMFETRVRGVLNDAVGKACA
SWPSLIEASSLLDKQKHNLLRHFEACDAVQSWRRRRAGSAGRKAVAP

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 48895; Mature: 48895

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLALDIYVGSLRAGLLFQYGTGSTALTRFIPDPSFWSRPDAPVLSWAATDDDPQRREI
CCEEEEEEEEHHHHHCEEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FWRSYVSTPFFNAEGGRLPAFFQNLLPEGPLRRHLEELRGCGPGDHFDLLAACGTDLPGN
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
VYAYPAHLDADALAAVVTQHNDALEMSVTADPLPEATSLSGVQPKLALVAQHGRYVARTR
EEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEHCC
DVQGTHIIAKLPTVEYALLPEVEELSLRLAQAAGADVCAAWLAPLEQIVAEQPFVLGESR
CCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
HFLVVRRFDRGPGGHIHCEDFAQILRIQPEEKYTHPAATYATMASTLRGGMGLGQRGEAA
CEEEEEEECCCCCCCEEHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHH
AEELIRRAMVNEMLGNYDAHVKNFGVLYRDGRTPELSPAYDVVAYAAYLGGRGHALRFVP
HHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECC
GGEKQARLTPQTVRSFCNATGMFETRVRGVLNDAVGKACASWPSLIEASSLLDKQKHNLL
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHFEACDAVQSWRRRRAGSAGRKAVAP
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNVLALDIYVGSLRAGLLFQYGTGSTALTRFIPDPSFWSRPDAPVLSWAATDDDPQRREI
CCEEEEEEEEHHHHHCEEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FWRSYVSTPFFNAEGGRLPAFFQNLLPEGPLRRHLEELRGCGPGDHFDLLAACGTDLPGN
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
VYAYPAHLDADALAAVVTQHNDALEMSVTADPLPEATSLSGVQPKLALVAQHGRYVARTR
EEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEHCC
DVQGTHIIAKLPTVEYALLPEVEELSLRLAQAAGADVCAAWLAPLEQIVAEQPFVLGESR
CCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
HFLVVRRFDRGPGGHIHCEDFAQILRIQPEEKYTHPAATYATMASTLRGGMGLGQRGEAA
CEEEEEEECCCCCCCEEHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHH
AEELIRRAMVNEMLGNYDAHVKNFGVLYRDGRTPELSPAYDVVAYAAYLGGRGHALRFVP
HHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECC
GGEKQARLTPQTVRSFCNATGMFETRVRGVLNDAVGKACASWPSLIEASSLLDKQKHNLL
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHFEACDAVQSWRRRRAGSAGRKAVAP
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]