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The map label for this gene is argE [H]

Identifier: 91788390

GI number: 91788390

Start: 2642803

End: 2644014

Strand: Reverse

Name: argE [H]

Synonym: Bpro_2527

Alternate gene names: 91788390

Gene position: 2644014-2642803 (Counterclockwise)

Preceding gene: 91788391

Following gene: 91788388

Centisome position: 50.84

GC content: 62.05

Gene sequence:

>1212_bases
ATGAGCACCCCATTCGATACGGCGAGCAACGAGAAACGGCCCTCGGCCGAACTGATGGCCATGATCGAGCGCCTGATCGC
ATTTCCGACCGTGTCGCGCGATTCCAATCTTGGGCTGATTGAGTGGACCCGCGACTATTTGGCGCAGATGGGTGTCAAGT
CACGGCTGACCTACGATTCGACCGGCAAAAAGGCGAACCTGTTTGCTACCCTGGGGGAGGGCCGCAGGCCGGGTCTGGTG
CTGTCGGGGCATACCGACGTGGTGCCGGTGGACGGGCAGGCCTGGGATACCGATCCCTTCAAGGCGACCGTGGTGGGCGA
CAAGCTGTTCGGCCGCGGCGTCGCCGACATGAAAAGCTACATCGCCACGGCGCTGGTCATGGCCCCCAAATTTCTGGCTG
CCAAGGCAGATGCACCGCTGCATCTGGCCTTGTCCTATGACGAGGAGGTCGGCTGCATCGGGGTGCGCGGCCTGATCAAG
GATTTGACCGAGATCGGCCTGAAAACCGCGGGCTGCATTGTTGGAGAACCGACACTGATGCAACCGATCATTGCGCACAA
GGGAACGCACCGTTTTCGCTGCTGCATCACGGGCCGCGAAGCGCACTCCAGCTACACCACGCAAGGCGTCAACTCGATTG
AATATGCCGCCCGCATCATTGTCTACATCCGCCAGATGGCGGACCGGCTGGCCCAGCTCGAGAGTCGCGATTATGCGTTC
ACGGTACCGTTCACCACGCTGCAGACCGGCACCATCAAGGGCGGGCTGGCGTCGAATATCGTGCCCCGGGACTGCGAGTT
CCAGTTCGAGGCGCGCACCATGCCGGGCGCGTCCTCCGACCGGCTGTACCAGGAAATCCAGGATTTTGCGGCAACCCTGC
TGCCGGAAATGAAACGGGTCGAGCCGAATGCCGCCATCCAGTTCGAAATGCTGGCCTCTGCGCCCGGCATGAGCATGGAA
GAAAGCGATGCCATCGTGAAGCTGGCGGCCTCCCTGTCACGCAACAAGCCGAACGGGGCGGTGTCGTACGGCACCGAGGG
CGGCCTGTTTCAGCAGGCCGGCATACCCACGGTGATATGCGGCCCCGGCAATATCGAGCAGGCGCATCGCCCGAATGAAT
TCGCCACCCTCGAACAAATTGCGCAATGTGAAGCCTTCATGCTGCGCCTGATTGAATCGGAGGCTGCAACGCCCCCTGAG
CGGCGGCATTAG

Upstream 100 bases:

>100_bases
TGCAGTGCTGAAAAGCCTGCCCTGAAAGAGGTGGCACCGACACATTTTTCGGCCTGTCACCTGAACGATCAACACTGAAC
CTTTTTGAAGGCCATTCATC

Downstream 100 bases:

>100_bases
AGCGAGGTTTCCAGCATCTCCCGGTATTCCTCGGGACTTGCCAGGCGCGGATTTGTCTTGTGACAGTGATCGGCCAGCGC
ACCCACGATGATGCGGTCAA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSTPFDTASNEKRPSAELMAMIERLIAFPTVSRDSNLGLIEWTRDYLAQMGVKSRLTYDSTGKKANLFATLGEGRRPGLV
LSGHTDVVPVDGQAWDTDPFKATVVGDKLFGRGVADMKSYIATALVMAPKFLAAKADAPLHLALSYDEEVGCIGVRGLIK
DLTEIGLKTAGCIVGEPTLMQPIIAHKGTHRFRCCITGREAHSSYTTQGVNSIEYAARIIVYIRQMADRLAQLESRDYAF
TVPFTTLQTGTIKGGLASNIVPRDCEFQFEARTMPGASSDRLYQEIQDFAATLLPEMKRVEPNAAIQFEMLASAPGMSME
ESDAIVKLAASLSRNKPNGAVSYGTEGGLFQQAGIPTVICGPGNIEQAHRPNEFATLEQIAQCEAFMLRLIESEAATPPE
RRH

Sequences:

>Translated_403_residues
MSTPFDTASNEKRPSAELMAMIERLIAFPTVSRDSNLGLIEWTRDYLAQMGVKSRLTYDSTGKKANLFATLGEGRRPGLV
LSGHTDVVPVDGQAWDTDPFKATVVGDKLFGRGVADMKSYIATALVMAPKFLAAKADAPLHLALSYDEEVGCIGVRGLIK
DLTEIGLKTAGCIVGEPTLMQPIIAHKGTHRFRCCITGREAHSSYTTQGVNSIEYAARIIVYIRQMADRLAQLESRDYAF
TVPFTTLQTGTIKGGLASNIVPRDCEFQFEARTMPGASSDRLYQEIQDFAATLLPEMKRVEPNAAIQFEMLASAPGMSME
ESDAIVKLAASLSRNKPNGAVSYGTEGGLFQQAGIPTVICGPGNIEQAHRPNEFATLEQIAQCEAFMLRLIESEAATPPE
RRH
>Mature_402_residues
STPFDTASNEKRPSAELMAMIERLIAFPTVSRDSNLGLIEWTRDYLAQMGVKSRLTYDSTGKKANLFATLGEGRRPGLVL
SGHTDVVPVDGQAWDTDPFKATVVGDKLFGRGVADMKSYIATALVMAPKFLAAKADAPLHLALSYDEEVGCIGVRGLIKD
LTEIGLKTAGCIVGEPTLMQPIIAHKGTHRFRCCITGREAHSSYTTQGVNSIEYAARIIVYIRQMADRLAQLESRDYAFT
VPFTTLQTGTIKGGLASNIVPRDCEFQFEARTMPGASSDRLYQEIQDFAATLLPEMKRVEPNAAIQFEMLASAPGMSMEE
SDAIVKLAASLSRNKPNGAVSYGTEGGLFQQAGIPTVICGPGNIEQAHRPNEFATLEQIAQCEAFMLRLIESEAATPPER
RH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=375, Percent_Identity=33.8666666666667, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1788816, Length=383, Percent_Identity=26.1096605744125, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43857; Mature: 43725

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPFDTASNEKRPSAELMAMIERLIAFPTVSRDSNLGLIEWTRDYLAQMGVKSRLTYDS
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCC
TGKKANLFATLGEGRRPGLVLSGHTDVVPVDGQAWDTDPFKATVVGDKLFGRGVADMKSY
CCCCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEECCHHHCCCHHHHHHH
IATALVMAPKFLAAKADAPLHLALSYDEEVGCIGVRGLIKDLTEIGLKTAGCIVGEPTLM
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHCCEEECCCHHH
QPIIAHKGTHRFRCCITGREAHSSYTTQGVNSIEYAARIIVYIRQMADRLAQLESRDYAF
HHHHHCCCCCEEEEEEECCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVPFTTLQTGTIKGGLASNIVPRDCEFQFEARTMPGASSDRLYQEIQDFAATLLPEMKRV
ECCCCEEECCCCCCCHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
EPNAAIQFEMLASAPGMSMEESDAIVKLAASLSRNKPNGAVSYGTEGGLFQQAGIPTVIC
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCEEECCCCCEEEE
GPGNIEQAHRPNEFATLEQIAQCEAFMLRLIESEAATPPERRH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STPFDTASNEKRPSAELMAMIERLIAFPTVSRDSNLGLIEWTRDYLAQMGVKSRLTYDS
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCC
TGKKANLFATLGEGRRPGLVLSGHTDVVPVDGQAWDTDPFKATVVGDKLFGRGVADMKSY
CCCCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEECCHHHCCCHHHHHHH
IATALVMAPKFLAAKADAPLHLALSYDEEVGCIGVRGLIKDLTEIGLKTAGCIVGEPTLM
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHCCEEECCCHHH
QPIIAHKGTHRFRCCITGREAHSSYTTQGVNSIEYAARIIVYIRQMADRLAQLESRDYAF
HHHHHCCCCCEEEEEEECCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVPFTTLQTGTIKGGLASNIVPRDCEFQFEARTMPGASSDRLYQEIQDFAATLLPEMKRV
ECCCCEEECCCCCCCHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
EPNAAIQFEMLASAPGMSMEESDAIVKLAASLSRNKPNGAVSYGTEGGLFQQAGIPTVIC
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCEEECCCCCEEEE
GPGNIEQAHRPNEFATLEQIAQCEAFMLRLIESEAATPPERRH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]