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The map label for this gene is ycgM [C]

Identifier: 91787997

GI number: 91787997

Start: 2215078

End: 2215773

Strand: Reverse

Name: ycgM [C]

Synonym: Bpro_2124

Alternate gene names: 91787997

Gene position: 2215773-2215078 (Counterclockwise)

Preceding gene: 91787998

Following gene: 91787996

Centisome position: 42.61

GC content: 61.78

Gene sequence:

>696_bases
ATGAGTTTTGTATTTACCCCGCCCGCCACGGTTTCCGTACCCGTTGTGGGAGTCAAAGAACGCTTTCCCGTCCACCGCAT
TTACTGCGTGGGCCGCAACTACGAAGAGCATGCCAAGGAGATGGGCTTCACTGGCCGCGAACCACCCTTCTTCTTCCTGA
AACCGGCAGACGCCCTCGTGGTGATTGACGCCGGTAGCACGGGCACCATTCCCTACCCGAGTCTCACCAACAACCTGCAT
CATGAAATCGAGCTGGTCGCGGCGATTGGCACGGGCGGCAAAAACATCAAGGCCGCCGATGCCCACAAGCACATCTACGG
CTACGCTGTGGGCCTGGACATGACACGCCGCGACTTGCAAGGCGAGATGAAAAAACAGGGCCGTCCCTGGTGCATCGGCA
AGGCCTATGACCACTCCGCGCCCATCGGCCCCATCACGCCCGTCGCCCAGGCCGGCGATGTGAGCAACGCCGAGATCTAC
CTGCAGGTCGGCGGAAAAGACCGCCAGCGCAGCAATGTCTCCAAGCTGATCTGGAACATTGCCGAAACCATAGAACACCT
GTCCGTGGCCTGGGAACTGCAGCCCGGCGACCTGATTTACACCGGCACCCCCGAGGGTGTGGCGGCGGTGGTGTCTGGCG
ACACCATGGTCGGCGGCGTGGCCGGCCTGGGTACGCTGACCGTCAAGGTCGCGTAA

Upstream 100 bases:

>100_bases
ACACTGCCCAACTGCACTCGCAGCAAGGTTGTGTGCTGTTCAGTTTTTCAGACCGCCCGGTGCATCAGGCCTTGGGCATA
CACAAAGAGGAAAGGTTGTC

Downstream 100 bases:

>100_bases
GCCCGACTGCCTGCGGGCAAGCGCCTTGCACCTGCGTTGTGCAGGGCGGCGTTCGCGGGCAGTTTGTGCGGTATACGCGC
AGCCGCTTCGATCATCGCGC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSFVFTPPATVSVPVVGVKERFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADALVVIDAGSTGTIPYPSLTNNLH
HEIELVAAIGTGGKNIKAADAHKHIYGYAVGLDMTRRDLQGEMKKQGRPWCIGKAYDHSAPIGPITPVAQAGDVSNAEIY
LQVGGKDRQRSNVSKLIWNIAETIEHLSVAWELQPGDLIYTGTPEGVAAVVSGDTMVGGVAGLGTLTVKVA

Sequences:

>Translated_231_residues
MSFVFTPPATVSVPVVGVKERFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADALVVIDAGSTGTIPYPSLTNNLH
HEIELVAAIGTGGKNIKAADAHKHIYGYAVGLDMTRRDLQGEMKKQGRPWCIGKAYDHSAPIGPITPVAQAGDVSNAEIY
LQVGGKDRQRSNVSKLIWNIAETIEHLSVAWELQPGDLIYTGTPEGVAAVVSGDTMVGGVAGLGTLTVKVA
>Mature_230_residues
SFVFTPPATVSVPVVGVKERFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADALVVIDAGSTGTIPYPSLTNNLHH
EIELVAAIGTGGKNIKAADAHKHIYGYAVGLDMTRRDLQGEMKKQGRPWCIGKAYDHSAPIGPITPVAQAGDVSNAEIYL
QVGGKDRQRSNVSKLIWNIAETIEHLSVAWELQPGDLIYTGTPEGVAAVVSGDTMVGGVAGLGTLTVKVA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=38.7254901960784, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=38.5786802030457, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=38.5786802030457, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI156231349, Length=213, Percent_Identity=31.924882629108, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI40786394, Length=213, Percent_Identity=31.4553990610329, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1787428, Length=210, Percent_Identity=38.5714285714286, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17557057, Length=195, Percent_Identity=37.9487179487179, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=217, Percent_Identity=33.1797235023041, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571789, Length=206, Percent_Identity=31.0679611650485, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28572127, Length=213, Percent_Identity=31.4553990610329, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24663695, Length=216, Percent_Identity=26.3888888888889, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24765; Mature: 24633

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVFTPPATVSVPVVGVKERFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADALV
CCEEECCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
VIDAGSTGTIPYPSLTNNLHHEIELVAAIGTGGKNIKAADAHKHIYGYAVGLDMTRRDLQ
EEECCCCCCCCCCHHCCCCCEEEEEEEEECCCCCCCEECCCCCEEEEEEEECCHHHHHHH
GEMKKQGRPWCIGKAYDHSAPIGPITPVAQAGDVSNAEIYLQVGGKDRQRSNVSKLIWNI
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
AETIEHLSVAWELQPGDLIYTGTPEGVAAVVSGDTMVGGVAGLGTLTVKVA
HHHHHHHEEEEEECCCCEEEECCCCCEEEEEECCEEECCEECCEEEEEEEC
>Mature Secondary Structure 
SFVFTPPATVSVPVVGVKERFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADALV
CEEECCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
VIDAGSTGTIPYPSLTNNLHHEIELVAAIGTGGKNIKAADAHKHIYGYAVGLDMTRRDLQ
EEECCCCCCCCCCHHCCCCCEEEEEEEEECCCCCCCEECCCCCEEEEEEEECCHHHHHHH
GEMKKQGRPWCIGKAYDHSAPIGPITPVAQAGDVSNAEIYLQVGGKDRQRSNVSKLIWNI
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
AETIEHLSVAWELQPGDLIYTGTPEGVAAVVSGDTMVGGVAGLGTLTVKVA
HHHHHHHEEEEEECCCCEEEECCCCCEEEEEECCEEECCEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]