Click here to switch to the map view.

The map label for this gene is alsR [H]

Identifier: 91787993

GI number: 91787993

Start: 2210784

End: 2211743

Strand: Direct

Name: alsR [H]

Synonym: Bpro_2120

Alternate gene names: 91787993

Gene position: 2210784-2211743 (Clockwise)

Preceding gene: 91787989

Following gene: 91788002

Centisome position: 42.51

GC content: 66.77

Gene sequence:

>960_bases
ATGGAACTGCGCCAGATTCGCTACTTCACCGTTCTCGCCGATGAGCTGAGCTTCACGCGGGCGGCGCGCCGGCTGCATGT
GTCGCAACCGCCCCTGAGCTTTCAGATTGCCAGCCTGGAGGCCGAACTCGGTGCGCGCCTGTTTAACCGTACCAGCCGCA
GTGTCGCGCTGAGCGAGGCGGGCAAGGCCTTTTTGCCGCATGCGCAAGCCGTGCTTGCGCGCCTGGAGGAGGCCCGCGGC
CACGTGCAGCGTGTGGCCAGCGGCCTGCAGGGACGGGTGCAGGTGGGCCTGGCGGGTTCGCACTTTCTGGGGCCATTTCC
GCAATTTATCCAGCAATTTCGCTTGCAGCGTCCCGCCGTCGAGATTGCGCTGCACGAGATGAAACCGTCCGACCATCTGC
AAGCCCTGCGCGACGGCCGGCTGGACCTGTGCGTCTCGCGCAATCCGCTGGAGGACGCGCAGATCAGCGCCGCGCTGTTA
TGGCGTGATCCGGTCGTGGTGGCCCTGCCGCCGGGTCATCGGCTGGCGGCGCGCAGCCGCCTGCGGCTGGCCGAGCTGAA
AGATGAAGAATTTGTCTTTCTGCGTCTGGACTCCTCGCCCTTCGCCGCACGCTTGTTCGAGGCTTGTGTGCAGGCGGGAT
TTGCTCCGCACATCGCACAACAGGTGGTCGAGGTGCCGGCCGCGCTCAACCTGGTGGCGGCGGGCCTGGGCGTGGCCCTG
GTGCCGGCTTCATTGGCGCAGCTGCGTGCCGATGCGGTGGGCATATGCAGCCTCAGCCCATCCATGCCCAAGCGCGCACA
GGCGGAAGGCAAGGCGAAAATGACGGGCGGCCTGAACGGGAACGCTCCGGGCGCCATCAATGGTGATGTGTACGTGCTGT
GGCGTCGCGAGGACGCAGCGCCTGCGGTGGCGACGTTCAGGACGCAGCTGCTGGACTGGGCACGCGCTTTACCGCCGTAG

Upstream 100 bases:

>100_bases
CTTGTCTCCTGGGTGGCTGGGGATTTGCCTATTCTTGGTGGTTTGATCCATACTGGCAAATACATAATCAAGATAAATCC
ATACCTGAAACAGATCGATC

Downstream 100 bases:

>100_bases
ACGGGGCGTTGATGGCCTGCGCTGATTTGCTATCAAGTTAATAGCTAATTGCCCCGTTTTTTTGGAAGCTGGGCGGCAAA
AACCATAAAAAAAACCGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MELRQIRYFTVLADELSFTRAARRLHVSQPPLSFQIASLEAELGARLFNRTSRSVALSEAGKAFLPHAQAVLARLEEARG
HVQRVASGLQGRVQVGLAGSHFLGPFPQFIQQFRLQRPAVEIALHEMKPSDHLQALRDGRLDLCVSRNPLEDAQISAALL
WRDPVVVALPPGHRLAARSRLRLAELKDEEFVFLRLDSSPFAARLFEACVQAGFAPHIAQQVVEVPAALNLVAAGLGVAL
VPASLAQLRADAVGICSLSPSMPKRAQAEGKAKMTGGLNGNAPGAINGDVYVLWRREDAAPAVATFRTQLLDWARALPP

Sequences:

>Translated_319_residues
MELRQIRYFTVLADELSFTRAARRLHVSQPPLSFQIASLEAELGARLFNRTSRSVALSEAGKAFLPHAQAVLARLEEARG
HVQRVASGLQGRVQVGLAGSHFLGPFPQFIQQFRLQRPAVEIALHEMKPSDHLQALRDGRLDLCVSRNPLEDAQISAALL
WRDPVVVALPPGHRLAARSRLRLAELKDEEFVFLRLDSSPFAARLFEACVQAGFAPHIAQQVVEVPAALNLVAAGLGVAL
VPASLAQLRADAVGICSLSPSMPKRAQAEGKAKMTGGLNGNAPGAINGDVYVLWRREDAAPAVATFRTQLLDWARALPP
>Mature_319_residues
MELRQIRYFTVLADELSFTRAARRLHVSQPPLSFQIASLEAELGARLFNRTSRSVALSEAGKAFLPHAQAVLARLEEARG
HVQRVASGLQGRVQVGLAGSHFLGPFPQFIQQFRLQRPAVEIALHEMKPSDHLQALRDGRLDLCVSRNPLEDAQISAALL
WRDPVVVALPPGHRLAARSRLRLAELKDEEFVFLRLDSSPFAARLFEACVQAGFAPHIAQQVVEVPAALNLVAAGLGVAL
VPASLAQLRADAVGICSLSPSMPKRAQAEGKAKMTGGLNGNAPGAINGDVYVLWRREDAAPAVATFRTQLLDWARALPP

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=321, Percent_Identity=31.1526479750779, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788887, Length=271, Percent_Identity=33.210332103321, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI2367136, Length=265, Percent_Identity=32.4528301886792, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI157672245, Length=268, Percent_Identity=30.5970149253731, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790399, Length=245, Percent_Identity=30.6122448979592, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788297, Length=258, Percent_Identity=31.3953488372093, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=25.2066115702479, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=270, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787601, Length=183, Percent_Identity=31.6939890710383, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=26.2295081967213, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787530, Length=276, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=243, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082132, Length=143, Percent_Identity=29.3706293706294, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=106, Percent_Identity=39.622641509434, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34621; Mature: 34621

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQIRYFTVLADELSFTRAARRLHVSQPPLSFQIASLEAELGARLFNRTSRSVALSEA
CCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHEEHHHC
GKAFLPHAQAVLARLEEARGHVQRVASGLQGRVQVGLAGSHFLGPFPQFIQQFRLQRPAV
CCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHH
EIALHEMKPSDHLQALRDGRLDLCVSRNPLEDAQISAALLWRDPVVVALPPGHRLAARSR
HHHHHHCCCHHHHHHHHCCCEEEEECCCCCCHHHHHEEEEECCCEEEEECCCCHHHHHHH
LRLAELKDEEFVFLRLDSSPFAARLFEACVQAGFAPHIAQQVVEVPAALNLVAAGLGVAL
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VPASLAQLRADAVGICSLSPSMPKRAQAEGKAKMTGGLNGNAPGAINGDVYVLWRREDAA
HHHHHHHHHHHHEEEEECCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCC
PAVATFRTQLLDWARALPP
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELRQIRYFTVLADELSFTRAARRLHVSQPPLSFQIASLEAELGARLFNRTSRSVALSEA
CCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHEEHHHC
GKAFLPHAQAVLARLEEARGHVQRVASGLQGRVQVGLAGSHFLGPFPQFIQQFRLQRPAV
CCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHH
EIALHEMKPSDHLQALRDGRLDLCVSRNPLEDAQISAALLWRDPVVVALPPGHRLAARSR
HHHHHHCCCHHHHHHHHCCCEEEEECCCCCCHHHHHEEEEECCCEEEEECCCCHHHHHHH
LRLAELKDEEFVFLRLDSSPFAARLFEACVQAGFAPHIAQQVVEVPAALNLVAAGLGVAL
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VPASLAQLRADAVGICSLSPSMPKRAQAEGKAKMTGGLNGNAPGAINGDVYVLWRREDAA
HHHHHHHHHHHHEEEEECCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCC
PAVATFRTQLLDWARALPP
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]