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The map label for this gene is codA [H]

Identifier: 91787836

GI number: 91787836

Start: 2026011

End: 2027288

Strand: Reverse

Name: codA [H]

Synonym: Bpro_1960

Alternate gene names: 91787836

Gene position: 2027288-2026011 (Counterclockwise)

Preceding gene: 91787837

Following gene: 91787830

Centisome position: 38.98

GC content: 63.62

Gene sequence:

>1278_bases
ATGCTCGATTTACTGATCACCAACGCGACGTTGCCCGACGGCCGAACCAACATGTCTATTGCCGTGCAGGGCGGCCGCAT
CACCGCGGTGGAGCCTGGCCTCAGCGCCCCCGCCCATGAAACGGTAGATGCAGGCGGTTACCTGCTCAGCCCGCATTTTG
TGGACCCGCACTTCCACATGGACGCCACCCTCAGCTACGGCCTGCCGCGCGTCAACGAAAGCGGCACACTGCTCGAAGGC
ATCGCCGTGTGGGGCGAGCTGAAACCCACACTCACGGCCGACGCCATCATTGAACGCGCCCTCACCTACTGCGACTGGGC
CGTCGCCAAGGGCCTGCTGGCCATACGCAGCCATGTGGACACCAGCGACCCCAGCCTGCTGGCCGTGGACGCGCTGCTGG
AGGTCAAGAAACAAGTCGCGCCCTACATCGACCTGCAACTCGTCGCCTTCCCGCAAGACGGCGTACTGCGCACAAAAGGC
GGTGTGGACAACCTCAAGCGCGCGCTGGACAGGGGCGTGGACGTGGTCGGCGGCATCCCCCACTTTGAGCGTACTTCTGA
ACAGGGTGCCGCCAGCGTAAAGCTGCTCTGCGAAATCGCCGCCGAGCGCGACCTGCTGACAGACATGCACTGCGATGAGT
CCGACGACCCCCTCTCGCGCCACATCGAAACCCTGGCCTTTGAAACCCAGCGACTGGGCCTGCAGGGCCGCGTCAACGGC
TCGCACTGCACCTCCATGCACAGCATGGACAACTACTACGTGAGCAAGTTGATTCCGCTAATAGCCGAGTCTCAAGTCAG
CGTCATCGCCAACCCACTCATCAACATCACCCTGCAAGGCCGCCACGACACCTACCCCAAGCGCCGAGGCATGACCCGCG
TGCCCGAACTCATGGCCGCAGGCGTCAACGTCGCCTTCGGCCACGACTGCGTGATGGACCCCTGGTACGGCATGGGCAGC
GGCGACATGTTGGAGGTGGCCCACATGGGCCTGCATGTGGCGCAGATGACGAGCCAGAAAGGCATTCGCGCGTGCTTCGA
CGCGGTGACGACCACGGCTGCGAAGGTGATGCACCTGCAGGGCTACGGACTGGAAGTGGGTTGCGATGCGAGCTTTGTGC
TGCTGCAGGCGCGAGACACGGTGGAAGCGATTCGGTTGCGGGCGAATCGGTTGAAGGTATGGAAGAAGGGAACGCTGCTG
GCCGAGACGCCAGCGGCCACGGCGCAGTTGCGGATGCCACTGCGATCACCGGCAACCAGCTTTATGCCTTCCCGATAG

Upstream 100 bases:

>100_bases
CCGGCACGGTGTGGCGTGCTGGCTGGCAGCAGCGCTCCCGTTCCACTGACCACTGACCACTGACCACTGACCACTGACGC
ATTCCATCCGCGGAGGTTTC

Downstream 100 bases:

>100_bases
TGGCTTCACTGCCCGCAGAGTCGTTGGCCAGATCTTTTGCCAGGTGCGGCAGGTACTCCCGAACCAGCGTTTCCACCATG
TCCGCCTGCGCCAGGTCCTT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLDLLITNATLPDGRTNMSIAVQGGRITAVEPGLSAPAHETVDAGGYLLSPHFVDPHFHMDATLSYGLPRVNESGTLLEG
IAVWGELKPTLTADAIIERALTYCDWAVAKGLLAIRSHVDTSDPSLLAVDALLEVKKQVAPYIDLQLVAFPQDGVLRTKG
GVDNLKRALDRGVDVVGGIPHFERTSEQGAASVKLLCEIAAERDLLTDMHCDESDDPLSRHIETLAFETQRLGLQGRVNG
SHCTSMHSMDNYYVSKLIPLIAESQVSVIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYGMGS
GDMLEVAHMGLHVAQMTSQKGIRACFDAVTTTAAKVMHLQGYGLEVGCDASFVLLQARDTVEAIRLRANRLKVWKKGTLL
AETPAATAQLRMPLRSPATSFMPSR

Sequences:

>Translated_425_residues
MLDLLITNATLPDGRTNMSIAVQGGRITAVEPGLSAPAHETVDAGGYLLSPHFVDPHFHMDATLSYGLPRVNESGTLLEG
IAVWGELKPTLTADAIIERALTYCDWAVAKGLLAIRSHVDTSDPSLLAVDALLEVKKQVAPYIDLQLVAFPQDGVLRTKG
GVDNLKRALDRGVDVVGGIPHFERTSEQGAASVKLLCEIAAERDLLTDMHCDESDDPLSRHIETLAFETQRLGLQGRVNG
SHCTSMHSMDNYYVSKLIPLIAESQVSVIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYGMGS
GDMLEVAHMGLHVAQMTSQKGIRACFDAVTTTAAKVMHLQGYGLEVGCDASFVLLQARDTVEAIRLRANRLKVWKKGTLL
AETPAATAQLRMPLRSPATSFMPSR
>Mature_425_residues
MLDLLITNATLPDGRTNMSIAVQGGRITAVEPGLSAPAHETVDAGGYLLSPHFVDPHFHMDATLSYGLPRVNESGTLLEG
IAVWGELKPTLTADAIIERALTYCDWAVAKGLLAIRSHVDTSDPSLLAVDALLEVKKQVAPYIDLQLVAFPQDGVLRTKG
GVDNLKRALDRGVDVVGGIPHFERTSEQGAASVKLLCEIAAERDLLTDMHCDESDDPLSRHIETLAFETQRLGLQGRVNG
SHCTSMHSMDNYYVSKLIPLIAESQVSVIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYGMGS
GDMLEVAHMGLHVAQMTSQKGIRACFDAVTTTAAKVMHLQGYGLEVGCDASFVLLQARDTVEAIRLRANRLKVWKKGTLL
AETPAATAQLRMPLRSPATSFMPSR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=405, Percent_Identity=44.6913580246914, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1786517, Length=405, Percent_Identity=27.4074074074074, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46068; Mature: 46068

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLLITNATLPDGRTNMSIAVQGGRITAVEPGLSAPAHETVDAGGYLLSPHFVDPHFHM
CCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCCCEEECCCEECCCCCC
DATLSYGLPRVNESGTLLEGIAVWGELKPTLTADAIIERALTYCDWAVAKGLLAIRSHVD
CCCHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSDPSLLAVDALLEVKKQVAPYIDLQLVAFPQDGVLRTKGGVDNLKRALDRGVDVVGGIP
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEECCCCHHHHHHHHHCCCEEECCCC
HFERTSEQGAASVKLLCEIAAERDLLTDMHCDESDDPLSRHIETLAFETQRLGLQGRVNG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
SHCTSMHSMDNYYVSKLIPLIAESQVSVIANPLINITLQGRHDTYPKRRGMTRVPELMAA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GVNVAFGHDCVMDPWYGMGSGDMLEVAHMGLHVAQMTSQKGIRACFDAVTTTAAKVMHLQ
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GYGLEVGCDASFVLLQARDTVEAIRLRANRLKVWKKGTLLAETPAATAQLRMPLRSPATS
CCCEEECCCCEEEEEECHHHHHHHHHHHHHHEEEECCCEEEECCCCHHEEECCCCCCCCC
FMPSR
CCCCC
>Mature Secondary Structure
MLDLLITNATLPDGRTNMSIAVQGGRITAVEPGLSAPAHETVDAGGYLLSPHFVDPHFHM
CCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCCCEEECCCEECCCCCC
DATLSYGLPRVNESGTLLEGIAVWGELKPTLTADAIIERALTYCDWAVAKGLLAIRSHVD
CCCHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSDPSLLAVDALLEVKKQVAPYIDLQLVAFPQDGVLRTKGGVDNLKRALDRGVDVVGGIP
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEECCCCHHHHHHHHHCCCEEECCCC
HFERTSEQGAASVKLLCEIAAERDLLTDMHCDESDDPLSRHIETLAFETQRLGLQGRVNG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
SHCTSMHSMDNYYVSKLIPLIAESQVSVIANPLINITLQGRHDTYPKRRGMTRVPELMAA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GVNVAFGHDCVMDPWYGMGSGDMLEVAHMGLHVAQMTSQKGIRACFDAVTTTAAKVMHLQ
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GYGLEVGCDASFVLLQARDTVEAIRLRANRLKVWKKGTLLAETPAATAQLRMPLRSPATS
CCCEEECCCCEEEEEECHHHHHHHHHHHHHHEEEECCCEEEECCCCHHEEECCCCCCCCC
FMPSR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]