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The map label for this gene is lpsI [H]

Identifier: 91787784

GI number: 91787784

Start: 1965607

End: 1966314

Strand: Direct

Name: lpsI [H]

Synonym: Bpro_1905

Alternate gene names: 91787784

Gene position: 1965607-1966314 (Clockwise)

Preceding gene: 91787781

Following gene: 91787785

Centisome position: 37.8

GC content: 62.57

Gene sequence:

>708_bases
GTGAACAAACTTTTCCCCTCCGCGGCCGAGGCCCTCAAGGGCGTGGTCAAGGACGGCCAGCTGATGGCCGTCGGCGGCTT
TGGCCTTTGCGGCATTCCCGAGGCCCTGATCGACGCGCTGAAGGGCAGCGGCGTGAAGAACCTCTCGGTGATTTCCAACA
ATGCCGGCGTGGACGGCTTTGGCCTGGGCAAGCTGCTGGAGACGCGGCAGATCAAAAAAATGATTTCCAGCTATGTGGGC
GAGAACAAGGAGTTCGAGCGCCAGTACCTGGCAGGCGAGCTGGAGCTGGAGTTCACGCCCCAGGGCACGCTGGCCGAGAA
GCTGCGCGCCGGCGGCGCCGGCATTCCGGCCTTCTTCACCAAGACTGGCGTCGGTACGCTGGTGGCCGAAGGCAAGGAAT
TGCGCGAATTTGACGGTGAAACCTACGTGATGGAGCGCTCGCTGATGCCCGACGTCTCGCTGGTCAAGGCGCATGTGGCC
GATAAGTCCGGGAACCTGCGCTTCAACCTCACGGCCCGTAATTTCAACCCGGCCGCCGCGATGGCCGGCAAGGTCTGCAT
CGTCGAGGTGGAGAAGGTCGTCGAAGTCGGCGAGCTGGCGCCCGACGACATCCACCTGCCGGGCATTTACGTGCACCGCA
TCGTGCTCAATGCGCACCCCGAGAAGCGCATTGAAAAGCGGACCATTACCGAGAAAGCAGGAGTTTGA

Upstream 100 bases:

>100_bases
TGGGGGCTAACCTTTACGAAAAACTACGTATCAGAATACGTAGTATCGTACTGGATTGTTCCCCGTTGAACTACCGCTGA
ATTACATCAGGAGACTATTT

Downstream 100 bases:

>100_bases
CCATGCCTTGGACCCAAGACCAGATGGCGGCACGCGCCGCCCAGGAACTCGAAGACGGTTTTTACGTGAACCTCGGCATC
GGCATCCCGACCCTGGTGGC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNKLFPSAAEALKGVVKDGQLMAVGGFGLCGIPEALIDALKGSGVKNLSVISNNAGVDGFGLGKLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLMPDVSLVKAHVA
DKSGNLRFNLTARNFNPAAAMAGKVCIVEVEKVVEVGELAPDDIHLPGIYVHRIVLNAHPEKRIEKRTITEKAGV

Sequences:

>Translated_235_residues
MNKLFPSAAEALKGVVKDGQLMAVGGFGLCGIPEALIDALKGSGVKNLSVISNNAGVDGFGLGKLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLMPDVSLVKAHVA
DKSGNLRFNLTARNFNPAAAMAGKVCIVEVEKVVEVGELAPDDIHLPGIYVHRIVLNAHPEKRIEKRTITEKAGV
>Mature_235_residues
MNKLFPSAAEALKGVVKDGQLMAVGGFGLCGIPEALIDALKGSGVKNLSVISNNAGVDGFGLGKLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLMPDVSLVKAHVA
DKSGNLRFNLTARNFNPAAAMAGKVCIVEVEKVVEVGELAPDDIHLPGIYVHRIVLNAHPEKRIEKRTITEKAGV

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=246, Percent_Identity=54.0650406504065, Blast_Score=269, Evalue=1e-72,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=51.0204081632653, Blast_Score=228, Evalue=4e-60,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=43.1372549019608, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1787985, Length=239, Percent_Identity=25.9414225941423, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=54.9180327868852, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24655794, Length=247, Percent_Identity=51.8218623481781, Blast_Score=251, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21358325, Length=247, Percent_Identity=51.8218623481781, Blast_Score=251, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25195; Mature: 25195

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLFPSAAEALKGVVKDGQLMAVGGFGLCGIPEALIDALKGSGVKNLSVISNNAGVDGF
CCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCC
GLGKLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKELREFDGETYVMERSLMPDVSLVKAHVADKSGNLRFNLTARNFNPAAA
HCCCHHHHHCCHHHHHCCCCEEEEEHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHH
MAGKVCIVEVEKVVEVGELAPDDIHLPGIYVHRIVLNAHPEKRIEKRTITEKAGV
HHCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKLFPSAAEALKGVVKDGQLMAVGGFGLCGIPEALIDALKGSGVKNLSVISNNAGVDGF
CCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCC
GLGKLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKELREFDGETYVMERSLMPDVSLVKAHVADKSGNLRFNLTARNFNPAAA
HCCCHHHHHCCHHHHHCCCCEEEEEHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHH
MAGKVCIVEVEKVVEVGELAPDDIHLPGIYVHRIVLNAHPEKRIEKRTITEKAGV
HHCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]