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The map label for this gene is cynR [H]

Identifier: 91787696

GI number: 91787696

Start: 1881256

End: 1882188

Strand: Direct

Name: cynR [H]

Synonym: Bpro_1817

Alternate gene names: 91787696

Gene position: 1881256-1882188 (Clockwise)

Preceding gene: 91787695

Following gene: 91787697

Centisome position: 36.18

GC content: 64.31

Gene sequence:

>933_bases
ATGAGTCTTTCCGAGGCCGACATGCGGGTGCGCCACCTGCAGGAGACGGCCCTGCGTTATTTCTTCGAGGTAGCGCGCTG
CGGCTCACTGACGGAGGCCTCGGAACGGCTTCACGTGGCGACTTCGGCGATCAGCCGCCAGATTGCCGGGCTGGAGCAGG
CGCTGGGTACGGCGCTCTTTGAGCGGCATCCGCGCGGCATGGTGCTGAACGCGGCCGGCGAGATACTGGCAACGCACGCG
CGCCGGGCGAGCCTGGATGCGGAAAGAGCGATCCATGAGATCCTTGCCTTGCAAGGCCTGCGCTCGGGCAAGGTGCGAAT
CGCCGCATCAGAGGCATTTGCCAACGAGTTCCTGCCGCCGCTGATCATCGCATTCAGAGCCGCGAATGAGGGCATCGTTT
TCGAGTTGAATGTCGAGCCACCGGCCCAGGTGTCGGTGCGCGTTCGCGACGGCGATGCAGACATCGGATTGAGATTCAGT
CGTGTCCCGGACAAGGAGATCAAGGTTGAGTACCGCCAGCCGGCGCCCGTGCTGGCGCTGATGCGCCACGATCATCCCCT
GGCCCAGTCCCGGTCGGTCACGCTGGCGCAGATGAGCGCCTATCCGATGGTGCTGCCTGCACCGGACACGGCGGTGCGCC
AGATGATCGACATGGAGTGCAGCCGCCAGCAATTGCTGATGGAGTCCGTGCTGACCAGCAACAGCATGACGACGCAGCAC
AACTTTGTCGTGCATGGCGGCGGCATCACCTTCTGCGGCGAGGTGTCGGTGCGGCACCTGGTCGCTGCCGGCACGCTGGT
GGTGATTCCGATTCGCGATCACGGCATGGGCTTGCGCTACATCGAGGTGCAAACGCTGGCCGGCCGCAGCTTGCCGCAAG
CGGTGCAGTCCTTTCTCGACTATCTCAAGCAACGCCTGGCCGACCAGCCATAG

Upstream 100 bases:

>100_bases
CTTCTTGGGCGTGATGATGGTTCCGCGTTCTTGCGTTTTCGCAAAAATTACAGCGCTCGCATCATATAGTTGCCGGATCA
GAAACCATAAAAGGACCATC

Downstream 100 bases:

>100_bases
ACGGGTTTCGGGTTTTGATGCCACATCGCTAGCCGCAATACGGTTCAGTCAAGCCCTTGCCGCTGGTTTGTCATTCCCGG
ACTTGATCCGGGATCCATGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSLSEADMRVRHLQETALRYFFEVARCGSLTEASERLHVATSAISRQIAGLEQALGTALFERHPRGMVLNAAGEILATHA
RRASLDAERAIHEILALQGLRSGKVRIAASEAFANEFLPPLIIAFRAANEGIVFELNVEPPAQVSVRVRDGDADIGLRFS
RVPDKEIKVEYRQPAPVLALMRHDHPLAQSRSVTLAQMSAYPMVLPAPDTAVRQMIDMECSRQQLLMESVLTSNSMTTQH
NFVVHGGGITFCGEVSVRHLVAAGTLVVIPIRDHGMGLRYIEVQTLAGRSLPQAVQSFLDYLKQRLADQP

Sequences:

>Translated_310_residues
MSLSEADMRVRHLQETALRYFFEVARCGSLTEASERLHVATSAISRQIAGLEQALGTALFERHPRGMVLNAAGEILATHA
RRASLDAERAIHEILALQGLRSGKVRIAASEAFANEFLPPLIIAFRAANEGIVFELNVEPPAQVSVRVRDGDADIGLRFS
RVPDKEIKVEYRQPAPVLALMRHDHPLAQSRSVTLAQMSAYPMVLPAPDTAVRQMIDMECSRQQLLMESVLTSNSMTTQH
NFVVHGGGITFCGEVSVRHLVAAGTLVVIPIRDHGMGLRYIEVQTLAGRSLPQAVQSFLDYLKQRLADQP
>Mature_309_residues
SLSEADMRVRHLQETALRYFFEVARCGSLTEASERLHVATSAISRQIAGLEQALGTALFERHPRGMVLNAAGEILATHAR
RASLDAERAIHEILALQGLRSGKVRIAASEAFANEFLPPLIIAFRAANEGIVFELNVEPPAQVSVRVRDGDADIGLRFSR
VPDKEIKVEYRQPAPVLALMRHDHPLAQSRSVTLAQMSAYPMVLPAPDTAVRQMIDMECSRQQLLMESVLTSNSMTTQHN
FVVHGGGITFCGEVSVRHLVAAGTLVVIPIRDHGMGLRYIEVQTLAGRSLPQAVQSFLDYLKQRLADQP

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=224, Percent_Identity=31.6964285714286, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081904, Length=285, Percent_Identity=29.1228070175439, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=30.4054054054054, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=30.6772908366534, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788748, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788887, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788296, Length=267, Percent_Identity=27.3408239700375, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693105, Length=235, Percent_Identity=22.5531914893617, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790783, Length=271, Percent_Identity=25.0922509225092, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787879, Length=214, Percent_Identity=28.0373831775701, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34119; Mature: 33988

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSEADMRVRHLQETALRYFFEVARCGSLTEASERLHVATSAISRQIAGLEQALGTALF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHPRGMVLNAAGEILATHARRASLDAERAIHEILALQGLRSGKVRIAASEAFANEFLPP
HCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCH
LIIAFRAANEGIVFELNVEPPAQVSVRVRDGDADIGLRFSRVPDKEIKVEYRQPAPVLAL
HHHHEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCHHEEEEECCCCCHHHH
MRHDHPLAQSRSVTLAQMSAYPMVLPAPDTAVRQMIDMECSRQQLLMESVLTSNSMTTQH
HHCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
NFVVHGGGITFCGEVSVRHLVAAGTLVVIPIRDHGMGLRYIEVQTLAGRSLPQAVQSFLD
CEEEECCCEEEECCHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
YLKQRLADQP
HHHHHHCCCC
>Mature Secondary Structure 
SLSEADMRVRHLQETALRYFFEVARCGSLTEASERLHVATSAISRQIAGLEQALGTALF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHPRGMVLNAAGEILATHARRASLDAERAIHEILALQGLRSGKVRIAASEAFANEFLPP
HCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCH
LIIAFRAANEGIVFELNVEPPAQVSVRVRDGDADIGLRFSRVPDKEIKVEYRQPAPVLAL
HHHHEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCHHEEEEECCCCCHHHH
MRHDHPLAQSRSVTLAQMSAYPMVLPAPDTAVRQMIDMECSRQQLLMESVLTSNSMTTQH
HHCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
NFVVHGGGITFCGEVSVRHLVAAGTLVVIPIRDHGMGLRYIEVQTLAGRSLPQAVQSFLD
CEEEECCCEEEECCHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
YLKQRLADQP
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]